IP Library Granted Patent US 10,801,931
Granted Patent B2
US 10,801,931 · App. 15/757,551 · Granted Oct 13, 2020

Sample pretreatment system and control method therefor

Inventors: Hyoung-Seop Lee (Uijeongbu-si, KR); Sung-Hun Hong (Seoul, KR)
Assignee: NANOENTEK, INC.
G01N1/38B01F13/08B01F13/0827B01L3/502B01L9/00G01N1/28G01N1/44G01N35/10G01N35/1016H02N11/00B01F2215/0037B01L2200/026B01L2300/044B01L2300/046B01L2300/047B01L2300/0832B01L2400/043G01N2035/00534
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Quick Facts
Patent No.
US 10,801,931
App. No.
15/757,551
Granted
Oct 13, 2020
Kind
B2
Abstract

Disclosed are a system for pretreatment of sample and a method for controlling the same. The system for pretreatment of sample, including: a holder storage unit having a module holder on which a sample pretreatment module is seated; a cartridge accommodating portion for loading a cartridge therein, wherein the sample accommodated in a chamber of the sample pretreatment module is discharged and loaded into the cartridge; a magnetic force generating unit for generating a magnetic force to rotate the permanent magnet provided in the sample pretreatment module; and a penetration and discharge unit for penetrating the penetration membrane in the sample pretreatment module and discharging the sample by pressing the moving unit of the cap.

Claims (44)

1. A system for pretreatment of sample comprising:

a holder storage unit having a module holder on which a sample pretreatment module is seated;

a cartridge accommodating portion for loading a cartridge therein, wherein the sample accommodated in a chamber of the sample pretreatment module is discharged and loaded into the cartridge;

a magnetic force generating unit for generating a magnetic force to rotate the permanent magnet provided in the sample pretreatment module; and

a penetration and discharge unit for penetrating a penetration membrane in the sample pretreatment module and discharging the sample by pressing a moving unit of a cap,

wherein the penetration and discharge unit comprises:

an edge pressing portion for pressing a cap edge portion of the sample pretreatment module so as to penetrate the penetration membrane in the sample pretreatment module; and

a moving unit pressing portion for pressing the moving unit to discharge the sample.

2. A system for pretreatment of sample comprising:

a holder storage unit having a module holder on which a sample pretreatment module is seated;

a cartridge accommodating portion for loading a cartridge therein, wherein the sample accommodated in a chamber of the sample pretreatment module is discharged and loaded into the cartridge;

a magnetic force generating unit for generating a magnetic force to rotate the permanent magnet provided in the sample pretreatment module; and

a penetration and discharge unit for penetrating a penetration membrane in the sample pretreatment module and discharging the sample by pressing a moving unit of a cap,

wherein the module holder comprises a module heater surrounding an outside of the module holder for heating the sample pretreatment module.

3. The system according to claim 1 , wherein the penetration and discharge unit further comprises:

a first moving bar connected to the edge pressing portion;

a second moving bar connected to the moving unit pressing portion; and

a first motor for driving the first moving bar and the second moving bar,

wherein the first moving bar and the second moving bar are simultaneously moved away from each other or vice versa by operation of the first motor.

4. The system according to claim 3 , wherein the penetration and discharge unit further comprises a through hole formed in the center of the edge pressing portion, and wherein the moving unit pressing portion presses the moving unit as it moves by moving through the through hole.

5. The system according to claim 1 , wherein the magnetic force generating unit comprises:

a vortexing magnet rotatably installed on one side of the module holder; and

a second motor for rotating the vortexing magnet.

6. The system according to claim 1 , wherein the cartridge accommodating portion comprises

a cartridge holder capable of accommodating the cartridge therein, for loading or unloading the cartridge; and

a third motor for providing a driving force to move the cartridge holder toward a loading or unloading position.

7. The system according to claim 6 , wherein the cartridge accommodating portion further comprises a cartridge heater for heating the loaded cartridge, and the cartridge heater ascends or descends depending on loading or unloading of the cartridge.

8. The system according to claim 7 , further comprising: a heater connection portion surrounding at least some portion of the cartridge heater and adhering to the cartridge, wherein the heater connection portion has a larger area than the reaction area of the cartridge.

9. The system according to claim 8 , wherein the cartridge heater is provided to have an area including the area of the heater connection portion covering the reaction area of the cartridge.

10. The system according to claim 8 , wherein the heater connection portion is in a flat shape to adhere to the reaction area of the cartridge.

11. The system according to claim 10 , wherein the cartridge heater is in a flat shape to correspond to the contacting surface of the heater connection portion and the cartridge.

12. The system according to claim 1 , wherein the holder storage unit further comprises a fourth motor for providing a driving force for loading or unloading the sample pretreatment module mounted on the module holder by moving the module holder.

13. The system according to claim 1 , further comprising:

a counting sensor for detecting the number of times the sample is dropped.

14. A method for controlling a system for pretreatment of a sample comprising:

setting a cartridge into a cartridge holder and loading the cartridge into the cartridge accommodating portion;

setting a sample pretreatment module accommodating the sample in a chamber into a module holder and loading it into a holder storage unit;

rotating the permanent magnets provided in the chamber by rotating the vortexing magnet located at one side of the module holder;

penetrating a penetration membrane in the sample pretreatment module by pressing a cap edge portion of the sample pretreatment module; and

loading a sample into the cartridge by pressing a moving unit of a cap of the sample pretreatment module to discharge the sample.

15. The method according to claim 14 , further comprising:

heating the cartridge to maintain the cartridge at a predetermined temperature.

16. The method according to claim 14 , further comprising:

heating the sample pretreatment module mounted on the module holder and maintaining the sample pretreatment module at a predetermined temperature for a predetermined time.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2018
From: LEE, HYOUNG-SEOP; HONG, SUNG-HUN
To: NANOENTEK, INC.
Reel/Frame 045497/0304 →
Priority Claims (1)
KR 10-2015-0125867 · Sep 4, 2015 · national
Continuity (1)
Related Publication 20180259432A1 · Sep 13, 2018