Deep topical systemic nitric oxide therapy apparatus and method
A topical mixture that produces nitric oxide and a method for using the topical mixture to increase the vasodilation of a bloodstream via transdermal absorption of the nitric oxide. The nitric oxide can then affect subcutaneous tissues. The systemic vasodilation of a mammal may be increased via a topical application of an appropriate nitric oxide producing substance.
1. A method for increasing vasodilation comprising:
providing a mammal with an epidermal surface and a bloodstream having an initial systemic vasodilation of the bloodstream;
providing a first medium comprising a nitrite compound;
providing a second medium comprising at least two reducing agents;
creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide;
applying the mixture onto a first location of the epidermal surface of the mammal;
absorbing at least 500 ppm of nitric oxide transdermally within 10 minutes after the applying; and
increasing the systemic vasodilation of the bloodstream at a second, untreated location of the mammal as compared to the initial systemic vasodilation.
2. The method of claim 1 , wherein the epidermal surface is healthy skin.
3. The method of claim 1 , wherein the mixture includes a salt buffer concentration for prolonging the production of nitric oxide, wherein the salt used in the salt buffer includes at least one salt selected from a group consisting of sodium chloride and calcium chloride.
4. The method of claim 1 , further comprising treating the mammal for peripheral artery disease.
5. The method of claim 1 , further comprising covering the epidermal surface with a barrier after applying the mixture.
6. The method of claim 1 , wherein the first medium includes at least one nitrite selected from a group consisting of sodium nitrite and potassium nitrite.
7. The method of claim 1 , wherein the second medium includes at least two reducing agents selected from a group consisting of citric acid, ascorbic acid, phytic acid, acetic acid, formic acid, and lactic acid.
8. The method of claim 1 , wherein the first and second mediums further include a thickening agent derived from cellulose in an amount between 0.80% and 0.120%.
9. The method of claim 1 , wherein the first medium further comprises sodium bicarbonate.
10. A method for treating systemic hemodynamic disorders comprising:
providing a mammal with an epidermal surface and a bloodstream having a systemic hemodynamic disorder;
providing a first medium comprising a nitrite compound and sodium bicarbonate;
providing a second medium comprising a reducing agent;
creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide;
applying the mixture onto a first location of the epidermal surface of the mammal; and
increasing systemic vasodilation of the bloodstream at a second, unapplied location of the mammal to treat the systemic hemodynamic disorder.
11. The method of claim 10 , wherein the systemic hemodynamic disorder is peripheral artery disease.
12. The method of claim 10 , wherein the second medium includes at least two reducing agents selected from a group consisting of citric acid, ascorbic acid, phytic acid, acetic acid, formic acid, and lactic acid.
13. The method of claim 10 , wherein the mixture includes a salt buffer concentration for prolonging the production of nitric oxide, wherein the salt used in the salt buffer includes at least one salt selected from a group consisting of sodium chloride and calcium chloride.
14. The method of claim 10 , further comprising repeating the previous steps within three days.
15. A method for increasing vasodilation comprising:
providing a mammal with an epidermal surface and a bloodstream having an initial systemic vasodilation of the bloodstream;
providing a first medium comprising a nitrite compound;
providing a second medium comprising at least two reducing agents;
creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide, wherein the mixture also includes a salt buffer for prolonging the production of nitric oxide, wherein the salt used in the salt buffer includes at least one salt selected from a group consisting of sodium chloride and calcium chloride;
treating, by applying the mixture onto a first location of the epidermal surface of the mammal;
absorbing an effective amount of nitric oxide transdermally; and
increasing the systemic vasodilation of the bloodstream at a second, untreated location of the mammal as compared to the initial systemic vasodilation.
16. The method of claim 15 , wherein the epidermal surface is healthy skin.
17. The method of claim 15 , further comprising covering the epidermal surface with a barrier after applying the mixture.
18. The method of claim 15 , wherein the first medium further comprises sodium bicarbonate.
19. The method of claim 15 , wherein the first and second mediums further include a thickening agent derived from cellulose in an amount between 0.80% and 0.120%.