IP Library › Granted Patent US 10,869,934
Granted Patent B2
US 10,869,934 · App. 16/533,226 · Granted Dec 22, 2020

Antiproliferative compounds and conjugates made therefrom

Inventors: Ivar M. McDonald (Woodstock, CT); Prasanna Sivaprakasam (Lawrenceville, NJ); Christiana I. Iwuagwu (Hamden, CT); Kevin M. Peese (Haddam, CT); Heng Cheng (Fremont, CA); Naidu S. Chowdari (Sunnyvale, CA); Sanjeev Gangwar (Foster City, CA)
Assignee: Bristol-Myers Squibb Company
A61K47/6803C07D471/04C07D519/00C07F7/0814C07K5/06026
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Quick Facts
Patent No.
US 10,869,934
App. No.
16/533,226
Granted
Dec 22, 2020
Kind
B2
Abstract

A compound capable of inhibiting cell proliferation, having a structure according to formula (I) wherein the variables in formula (I) are as defined in the specification. Such compounds are useful as anti-cancer agents, especially in antibody-drug conjugates.

Claims (1)

1. A compound having a structure according to formula (Ib-54)

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 6, 2020
From: MCDONALD, IVAR M.; SIVAPRAKASAM, PRASANNA; IWUAGWU, CHRISTIANA I.; PEESE, KEVIN M.; CHENG, HENG; CHOWDARI, NAIDU S.; GANGWAR, SANJEEV
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 051739/0865 →
Continuity (3)
Continuation 15789027 · Oct 20, 2017
Provisional Application 62410624 · Oct 20, 2016
Related Publication 20190358339A1 · Nov 28, 2019
Cited By (6)
US 12,186,403 US 12,268,750 US 12,274,754 US 12,280,121 US 12,285,492 US 12,545,716