Radio frequency electro-thrombectomy device
A device is designed to remove blockages in a lumen such as a thrombus, blood clot, or embolus. The device comprises a manipulating wire and a structure that can conduct electrical current to a lumen blockage. The electrical current is preferably in radio frequency (RF). The RF electric current in the blockage can excite the contents such as proteins of the blockage, so that cross-linking density and interfacial adsorption of the entire blockage is enhanced. The enhanced cross-linking density can result in increased fracture resistance of the blockage such that fracture of the blockage during the removal process is unlikely. The enhanced interfacial adsorption results in increased interfacial fracture resistance between the device and blockage so that the blockage can be securely captured during the removal process without using radially applied force.
1. A method of removing a blockage from a vascular lumen, the method comprising the steps of
a) cross-linking a blockage in a vascular lumen using radio frequency by contacting the blockage with at least two wires made of electrically conductive material and applying a field or current that passes through the entire blockage to increase the cross-linking density of the entire blockage in a substantially uniform manner, and
b) capturing and removing the cross-linked blockage from the vascular lumen.
2. The method of claim 1 , wherein the radio frequency field or current is deployed from a RF-system or an electrical power source outside a body that comprises the vascular lumen.
3. The method of claim 1 , wherein the blockage is a thrombus, blood clot, or embolus.
4. The method of claim 1 , wherein the field or current is passed in a sinusoidal form, a continuous form, or a step form.
5. The method of claim 2 , wherein the cross-linked blockage is removed from the vascular lumen retrograde through a catheter.