IP Library Granted Patent US 10,918,656
Granted Patent B2
US 10,918,656 · App. 16/862,662 · Granted Feb 16, 2021

Therapeutic agent for dry eye characterized by being applied to eye of dry eye patient wearing soft contact lens

Inventors: Yoshihiro Oshita (Osaka, JP); Hitoshi Nakazawa (Ikoma, JP); Isao Matsuoka (Ikoma, JP); Asuka Kamimura (Ikoma, JP)
Assignee: SANTEN PHARMACEUTICAL CO., LTD.
A61K31/7084A61K9/0048A61K47/10A61K47/14A61P27/04
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Quick Facts
Patent No.
US 10,918,656
App. No.
16/862,662
Granted
Feb 16, 2021
Kind
B2
Abstract

An ophthalmic solution, which comprises diquafosol tetrasodium salt and is free from benzalkonium chloride, treats onset and/or exacerbation of dry eye symptom caused by wearing soft contact lenses.

Claims (4)

1. A method of ameliorating eye dryness or eye discomfort caused by wearing soft contact lens comprising administering an ophthalmic solution which comprises a therapeutically effective amount of diquafosol or a salt thereof alone as a sole active ingredient and does not comprise benzalkonium chloride to an eye wearing soft contact lens, wherein a concentration of the diquafosol or a salt thereof is 3% (w/v) and the solution comprises a buffer, an isotonicity agent, a stabilizer and a pH adjuster.

2. The method according to claim 1 , wherein the ophthalmic solution does not comprise a preservative.

3. The method according to claim 1 , wherein the ophthalmic solution is contained in a unit-dose type container.

4. The method according to claim 1 , wherein the ophthalmic solution is contained in a multi-dose type container.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 30, 2020
From: OSHITA, YOSHIHIRO; NAKAZAWA, HITOSHI; MATSUOKA, ISAO; KAMIMURA, ASUKA
To: SANTEN PHARMACEUTICAL CO., LTD.
Reel/Frame 052533/0817 →
Priority Claims (1)
JP 2015-114596 · Jun 5, 2015 · national
Continuity (2)
Continuation 15579481
Related Publication 20200254000A1 · Aug 13, 2020