IP Library Granted Patent US 10,940,310
Granted Patent B2
US 10,940,310 · App. 16/357,033 · Granted Mar 9, 2021

Nasal stimulation for rhinitis, nasal congestion, and ocular allergies

Inventors: James Donald Loudin (Houston, TX); Daniel N. Hamilton (Napa, CA); Manfred Franke (Valencia, CA); Douglas Michael Ackermann (San Francisco, CA)
Assignee: Oculeve, Inc.
A61N1/0546A61N1/36014A61N1/0456A61N1/36034
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Quick Facts
Patent No.
US 10,940,310
App. No.
16/357,033
Granted
Mar 9, 2021
Kind
B2
Abstract

Described here are devices, systems, and methods for treating one or more conditions, such as allergic rhinitis, non-allergic rhinitis, nasal congestion, ocular allergy, and/or symptoms associated with these conditions, by providing stimulation to nasal or sinus tissue. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs, and the nasal insertion prongs may be configured to deliver an electrical stimulus to the tissue.

Claims (29)

1. A method for treating an ocular condition, the method comprising:

contacting a stimulating portion of a handheld stimulator to external nasal tissue of a nose of a subject, the stimulating portion extending from a stimulator body of the handheld stimulator; and

delivering a stimulus via the stimulating portion to the external nasal tissue to activate an anterior ethmoidal nerve, thereby improving the ocular condition of the subject, wherein the stimulator body of the handheld stimulator comprises a control subsystem to control the stimulus.

2. The method of claim 1 , wherein the stimulus is delivered in response to one or more symptoms of the ocular condition.

3. The method of claim 2 , wherein the one or more symptoms of the ocular condition comprise one or more of itching, sneezing, congestion, runny nose, post-nasal drip, mouth breathing, coughing, fatigue, headache, anosmia, phlegm, throat irritation, periorbital puffiness, watery eyes, ear pain, and fullness sensation.

4. The method of claim 1 , wherein the ocular condition comprises rhinitis.

5. The method of claim 1 , wherein the ocular condition comprises an ocular allergy.

6. The method of claim 1 , wherein the stimulus is delivered more than once per day on a scheduled basis.

7. The method of claim 1 , wherein the stimulating portion comprises a first electrode and a second electrode.

8. The method of claim 1 , wherein the stimulus is a biphasic pulse waveform.

9. The method of claim 8 , wherein the biphasic pulse waveform is symmetrical.

10. The method of claim 8 , wherein the biphasic pulse waveform has a varying peak to peak amplitude.

11. The method of claim 8 , wherein the biphasic pulse waveform has a varying frequency.

12. The method of claim 1 , wherein the stimulus is pulsed.

13. The method of claim 1 , wherein the stimulating portion is releasably coupled to the stimulator body.

14. A method for treating an ocular condition, the method comprising:

contacting an electrode of a handheld stimulator to external nasal skin of a nose of a subject, the electrode being coupled to a stimulator body of the handheld stimulator; and

delivering an electrical stimulus via the electrode to the external nasal skin of the subject to activate an anterior ethmoidal nerve, thereby improving the ocular condition of the subject.

15. The method of claim 14 , wherein the electrical stimulus is delivered in response to one or more symptoms of the ocular condition.

16. The method of claim 15 , wherein the one or more symptoms of the ocular condition comprise one or more of itching, sneezing, congestion, runny nose, post-nasal drip, mouth breathing, coughing, fatigue, headache, anosmia, phlegm, throat irritation, periorbital puffiness, watery eyes, ear pain, and fullness sensation.

17. The method of claim 15 , wherein the electrical stimulus is a biphasic pulse waveform.

18. The method of claim 14 , wherein the ocular condition comprises rhinitis.

19. The method of claim 14 , wherein the ocular condition comprises an ocular allergy.

20. The method of claim 14 , wherein the electrical stimulus is delivered more than once per day on a scheduled basis.

21. The method of claim 14 , wherein the electrical stimulus is pulsed.

22. The method of claim 21 , wherein the biphasic pulse waveform is symmetrical.

23. The method of claim 21 , wherein the biphasic pulse waveform has a varying peak to peak amplitude.

24. The method of claim 21 , wherein the biphasic pulse waveform has a varying frequency.

25. The method of claim 14 , wherein the electrode is releasably coupled to the stimulator body.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 7, 2020
From: ACKERMANN, DOUGLAS MICHAEL; LOUDIN, JAMES DONALD; FRANKE, MANFRED; HAMILTON, DANIEL N.
To: OCULEVE, INC.
Reel/Frame 053143/0175 →
Continuity (3)
Continuation 15438577 · Feb 21, 2017
Provisional Application 62297734 · Feb 19, 2016
Related Publication 20190308009A1 · Oct 10, 2019
Cited By (1)
US 12,357,817