Food composition for suppressing hepatic lipogenesis
A peptide having an effect of suppressing hepatic lipogenesis, where a peptide is one or two or more peptides selected from 11 dipeptides (Ala-Gly, His-Asn, His-Ser, His-Thr, His-Trp, Val-Met, Trp-Glu, Trp-Lys, Tyr-Lys, Tyr-Ser and Tyr-Tyr) and 25 tripeptides (Val-Ile-Leu, Gly-Ser-Leu, Val-Leu-Gln, His-Ala-Gln, Arg-Ala-Val, Lys-Leu-Gly, Ile-Val-Ile, Lys-Pro-Ile, Leu- Val-Ile, Leu-Arg-Asp, Gln-Glu-Glu, Ser-Gly-Glu, Arg-Trp-Phe, Asp-Phe-Phe, Asp-Val-Phe, Pro-Phe-Tyr, Phe-Ile-Arg, Asn-Gly-Arg, Ile-Ile-Pro, Ile-Asp-Arg, Ile-His-Arg, Ile-Asp-Arg, Asn-Arg-Val, Ser-Ser-Val and Val-Phe-Val), is provided. The peptide may be used in a food composition for suppressing hepatic lipogenesis and an agent for suppressing hepatic lipogenesis.
1. A method for suppressing hepatic lipogenesis in a subject in need thereof, comprising administering to the subject an agent for suppressing hepatic lipogenesis comprising one or more peptide selected from the group consisting of His-Asn, His-Ser, His-Thr, His-Trp, Trp-Glu, Trp-Lys, Tyr-Lys, Tyr-Ser, and Tyr-Tyr, as an active ingredient.
2. The method according to claim 1 , wherein the peptide as an active ingredient is one or more dipeptide selected from the group consisting of His-Asn, His-Ser, His-Thr, His-Trp, Tyr-Lys, Tyr-Ser and Tyr-Tyr.
3. The method according to claim 1 , wherein the peptide as an active ingredient is one or more dipeptide selected from the group consisting of His-Asn, His-Ser, His-Thr, His-Trp, Trp-Glu, and Trp-Lys.
4. The method according to claim 1 , wherein the peptide as an active ingredient is one or more dipeptide selected from the group consisting of His-Asn, His-Ser, His-Thr, and His-Trp.