IP Library Granted Patent US 11,065,645
Granted Patent B2
US 11,065,645 · App. 15/568,684 · Granted Jul 20, 2021

Method and system for generating mechanical pulses

Inventors: Martin Brouillette (Sherbrooke, CA); Steven Dion (Sherbrooke, CA); Louis-Philippe Riel (Montreal, CA)
Assignee: Les Solutions Medicales Soundbite Inc.
B06B3/00A61B17/22004A61B17/22012B06B1/0215B06B1/0607B06B1/0633G10K11/24G10K11/28G10K15/043A61B2017/00477A61B2017/22008A61B2017/22018A61B2017/22024A61B2017/22027A61B2017/22028B06B2201/76
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Quick Facts
Patent No.
US 11,065,645
App. No.
15/568,684
Granted
Jul 20, 2021
Kind
B2
Abstract

A method for generating a mechanical wave, including generating a high amplitude mechanical pulse; coupling the mechanical pulse in a proximal end of a transmission member; propagating the mechanical pulse into the transmission member from the proximal end and a distal end thereof; and transmitting the mechanical pulse at the distal end.

Claims (32)

1. A method for generating a mechanical wave for treating a lesion in a blood vessel, comprising:

generating, using a wave generator, at least one high amplitude broadband mechanical pulse;

coupling the at least one high amplitude broadband mechanical pulse into a proximal end of a non-dispersive transmission member, at least a section of the non-dispersive transmission member being inserted into the blood vessel, a distal end of the non-dispersive transmission member being positioned adjacent to the lesion in the blood vessel;

propagating the at least one high amplitude broadband mechanical pulse into the non-dispersive transmission member from the proximal end to the distal end thereof; and

transmitting the at least one high amplitude mechanical pulse at the distal end of the non-dispersive transmission member to thereby treat the lesion.

2. The method of claim 1 , wherein the at least one high amplitude broadband mechanical pulse each have a center frequency f c comprised between about 20 kHz and about 10 MHz and a duration of about 1/f c .

3. The method of claim 1 , wherein an amplitude of the at least one high amplitude broadband mechanical pulse when reaching the distal end of the non-dispersive transmission member is comprised between about 10 MPa and about 1000 MPa.

4. The method of claim 1 , wherein said generating comprises generating a plurality of broadband mechanical waves having a first amplitude and combining the plurality of broadband mechanical waves, thereby obtaining the at least one high amplitude broadband mechanical pulse each having a second amplitude greater than the first amplitude.

5. The method of claim 4 , wherein said combining comprises focusing the plurality of broadband mechanical waves on a focus zone.

6. The method of claim 5 , wherein said focusing comprising reflecting the plurality of broadband mechanical waves on a parabolic surface.

7. The method of claim 4 , wherein said combining comprising propagating the plurality of broadband mechanical waves into a temporal concentrator.

8. The method of claim 4 , wherein said combining comprises propagating the plurality of broadband mechanical waves in a taper.

9. The method of claim 4 , wherein said combining comprises propagating the plurality of broadband mechanical waves in a reverberating cavity.

10. The method of claim 4 , wherein said combining comprises propagating the plurality of broadband mechanical waves in a dispersive medium.

11. The method of claim 1 , wherein the non-dispersive transmission member has an aspect ratio equal to or greater than 1000.

12. A system for generating a mechanical wave for treating a lesion in a blood vessel, comprising:

a pulse generator for generating at least one high amplitude broadband; and

a non-dispersive transmission member extending between a proximal end and a distal end, the proximal end being coupled to the pulse generator for receiving the at least one high amplitude broadband mechanical pulse therefrom, at least a section of the non-dispersive transmission member being sized and shaped to be insertable into the blood vessel, the distal end of the non-dispersive transmission member being positionable adjacent to the lesion, the non-dispersive transmission member for propagating the at least one high amplitude broadband mechanical pulse from the proximal end to the distal end and transmitting the at least one high amplitude broadband mechanical pulse at the distal end to thereby treat the lesion.

13. The system of claim 12 , wherein the at least one high amplitude broadband mechanical pulse each have a center frequency f c comprised between about 20 kHz and about 10 MHz and a duration of about 1/f c .

14. The system of claim 12 , wherein an amplitude of the at least one high amplitude broadband mechanical pulse when reaching the distal end of the non-dispersive transmission member is comprised between about 10 MPa and about 1000 MPa.

15. The system of claim 12 , wherein the pulse generator comprises:

a plurality of broadband sources each for emitting a respective broadband mechanical wave having a first amplitude; and

a wave concentrator for combining the broadband mechanical waves in order to obtain the at least one high amplitude broadband mechanical pulse having a second amplitude greater than the first amplitude.

16. The system of claim 15 , wherein the wave concentrator is a spatial concentrator.

17. The system of claim 15 , wherein the wave concentrator is a temporal concentrator.

18. The system of claim 15 , wherein the wave concentrator is adapted to focus the mechanical waves on a focus zone adjacent to the proximal end of the non-dispersive transmission member.

19. The system of claim 18 , wherein the wave concentrator comprises a parabolic reflecting surface for reflecting at least some of the plurality of broadband mechanical waves generated by the plurality of broadband sources towards the focus zone.

20. The system of claim 15 , wherein the wave concentrator is a taper.

21. The system of claim 15 , wherein the wave concentrator comprises a spatial concentration stage and a temporal concentration stage.

22. The system of claim 15 , wherein the wave concentrator comprises a reverberating cavity.

23. The system of claim 15 , wherein the wave concentrator comprises a dispersive medium.

24. The system of claim 12 , wherein the non-dispersive transmission member has an aspect ratio equal to or greater than 1000.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2025
From: LES SOLUTIONS MEDI CALES SOUND BITE INC.
To: VFLO MACAO LIMITED
Reel/Frame 071889/0252 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2022
From: SOCPRA SCIENCES ET GÉNIE S.E.C.
To: LES SOLUTIONS MÉDICALES SOUNDBITE INC.
Reel/Frame 059693/0486 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2022
From: UNIVERSITÉ DE SHERBROOKE
To: SOCPRA SCIENCES ET GÉNIE S.E.C
Reel/Frame 059665/0748 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2022
From: BROUILLETTE, MARTIN; DION, STEVEN; RIEL, LOUIS-PHILIPPE
To: UNIVERSITÉ DE SHERBROOKE
Reel/Frame 059289/0789 →
Continuity (2)
Provisional Application 62152332 · Apr 24, 2015
Related Publication 20180147606A1 · May 31, 2018
Cited By (5)
US 12,396,742 US 12,402,901 US 12,594,406 US 12,642,946 US 12,714,836