Ocular treatment devices and related methods of use

1. A medical device comprising:

a microcannula having a proximal end, a distal tip, and a cavity, the microcannula having a central longitudinal axis;

a handle coupled to the proximal end of the microcannula;

a plurality of orifices extending circumferentially about the distal tip of the microcannula, the plurality of orifices each defining a channel extending transverse to the central longitudinal axis and having a radially outer end positioned radially farther away from the central longitudinal axis than a radially inner end, and the plurality of orifices each configured to deliver a substance radially outwardly from the distal tip of the microcannula;

one or more grooves about a circumference of the microcannula;

an outer tube, wherein the microcannula is housed within the outer tube, the outer tube comprising an opening located at a distal end of the outer tube; and

a control mechanism located proximal to the handle, the control mechanism configured to move the outer tube from a first position to a second position, wherein a first orifice is covered in the first position and the first orifice is exposed in the second position.

2. The medical device of claim 1 , wherein an outer diameter of the microcannula varies along a length of the microcannula.

3. The medical device of claim 1 , wherein a first orifice among the plurality of orifices is spaced 180 degrees apart from a second orifice among the plurality of orifices.

4. The medical device of claim 1 , wherein the plurality of orifices are disposed at the same distance from the distal tip on the central longitudinal axis.

5. The medical device of claim 1 , wherein the substance is a viscoelastic fluid, wherein the handle comprises a reservoir containing the viscoelastic fluid, and an actuator configured to eject the viscoelastic fluid radially outwardly through the orifices.

6. The medical device of claim 1 , wherein the radially outer end is positioned distal to the radially inner end, such that each of the orifices is configured to deliver the substance distally and radially outwardly from the microcannula.

7. The medical device of claim 1 , wherein a first outer diameter of the microcannula tapers down to a second outer diameter of the microcannula at an end of the distal tip, wherein a distance between the first outer diameter and the second outer diameter along the central longitudinal axis is less than the first outer diameter.

8. The medical device of claim 7 , wherein the first outer diameter is between 500 μm and 700 μm, and wherein the second outer diameter is between 100 μm and 200 μm.

9. The medical device of claim 1 , further comprising one or more grooves located at the distal tip of the microcannula.

10. The medical device of claim 9 , wherein each of the one or more grooves has a depth between 15 μm and 35 μm.

11. The medical device of claim 9 , wherein each of the one or more grooves is formed proximal to the orifices.

12. The medical device of claim 9 , wherein the one or more grooves comprises at least three grooves that are equidistantly spaced apart.

13. The medical device of claim 1 , further comprising:

an outer cannula having a distal end, and a cavity, the outer cannula having a central longitudinal axis, and one or more protrusions, the one or more protrusions of the outer cannula extending circumferentially at the distal end of the outer cannula and located in the cavity of the outer cannula.

14. The medical device of claim 13 , wherein the microcannula is moveably housed within the outer cannula, and wherein one or more protrusions are located on an outer circumferential surface of the microcannula.

15. The medical device of claim 14 , wherein the one or more protrusions of one of the outer cannula and the microcannula include multiple protrusions equidistantly spaced apart.

16. The medical device of claim 14 , wherein the one or more protrusions of the microcannula are proximal to the one or more protrusions of the outer cannula when the distal tip of the microcannula is within the outer cannula.

17. The medical device of claim 14 , wherein the one or more protrusions of the microcannula are distal to the one or more protrusions of the outer cannula when at least a portion of the distal tip of the microcannula is moved outside of the distal end of the outer cannula.

18. A method of delivering fluid, comprising: inserting a microcannula through an incision in an anterior chamber of an eye, the microcannula including a proximal end, a distal tip, and a cavity, the microcannula having a central longitudinal axis with the proximal end of the microcannula being coupled to a handle and one or more grooves located at the distal tip of the microcannula; advancing the distal tip of the microcannula through a trabecular meshwork of the eye and into Schlemm's canal of the eye; delivering fluid through a plurality of orifices positioned within the Schlemm's canal, the plurality of orifices extending circumferentially about the distal tip of the microcannula, the plurality of orifices each defining a channel extending transverse to the central longitudinal axis and having a radially outer end positioned radially farther away from the central longitudinal axis than a radially inner end such that the fluid is delivered radially outwardly from the distal tip of the microcannula; and moving, by a control mechanism located proximal to the handle, an outer tube housing the microcannula to one of a first position that exposes a first orifice and a second position that covers the first orifice.

19. The method of claim 18 , wherein the microcannula includes one or more protrusions located on an outer circumferential surface of the microcannula,

wherein the microcannula is movably housed within the outer tube, the outer tube having one or more protrusions extending circumferentially at a distal end of the outer tube and located in a cavity of the outer tube, and wherein advancing the distal tip of the microcannula further comprises:

applying a force to the microcannula to move the one or more protrusions of the microcannula distal to the one or more protrusions of the outer tube.