Medicament container and method for producing same
The present disclosure relates to a method for producing, filling and sealing a medicament container. The method includes a blow-fill seal process including inflating a parison within a mold to form the medicament container, filling a medicament into the medicament container, and sealing a distal end of a neck of the medicament container, wherein the mold is dimensioned such that the neck is formed with an internal radius small enough to allow for a capillary effect of the medicament so that an air bubble remaining in the neck after filling and sealing the medicament container is fixed within the neck (by capillary forces. The present disclosure also relates to a medicament container produced by said method.
1. A method for producing, filling and sealing a medicament container, the method comprising:
inflating a parison within a mold to form the medicament container;
filling a medicament into the medicament container; and
sealing a distal end of a neck of the medicament container,
wherein the mold is dimensioned such that the neck of the medicament container is formed with an internal radius small enough to allow for a capillary effect of the medicament so that an air bubble remaining in the neck after filling and sealing the medicament container is fixed within the neck by capillary forces.
2. The method according to claim 1 , wherein the mold is dimensioned such that the neck is formed with an internal radius small enough to allow for a capillary effect of the medicament with a capillary pressure of at least 100 mBar.
3. The method according to claim 1 , wherein the mold is dimensioned such that the neck is formed with an internal radius of at most 1.4 mm.
4. The method according to claim 1 , wherein the mold is dimensioned such that the neck is formed with a length of 7 mm to 30 mm.
5. A method for producing, filling and sealing a medicament container, the method comprising:
inflating a parison within a mold to form the medicament container;
filling a medicament into the medicament container; and
sealing a distal end of a neck of the medicament container,
wherein the mold is dimensioned such that the neck of the medicament container is formed with an internal radius small enough to allow for a capillary effect of the medicament so that an air bubble remaining in the neck after filling and sealing the medicament container is fixed within the neck by capillary forces, and wherein during sealing, the neck is cut through a section holding the air bubble.
6. The method according to claim 5 , wherein the mold is dimensioned such that the neck is formed with an internal radius small enough to allow for a capillary effect of the medicament with a capillary pressure of at least 100 mBar.
7. The method according to claim 5 , wherein the mold is dimensioned such that the neck is formed with an internal radius of at most 1.4 mm.
8. The method according to claim 5 , wherein the mold is dimensioned such that the neck is formed with a length of 7 mm to 30 mm.