Vaccine for protection against
The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis , for use in a method for protecting piglets having maternally derived anti- Streptococcus suis antibodies against Streptococcus suis , by administering the vaccine to the piglets at an age of at most 28 days, preferably before the piglets are weaned.
1. A method for protecting piglets having maternally derived anti- Streptococcus suis antibodies against Streptococcus suis , comprising administering a vaccine comprising an IgM protease antigen of Streptococcus suis to the piglets at an age of at most 28 days.
2. The method of claim 1 , comprising administering one shot of the vaccine.
3. The method of claim 1 , wherein the administering of the vaccine is before an age at which the piglets are weaned.
4. The method of claim 1 , wherein the method is for conferring protection against clinical signs associated with a pathogenic infection with Streptococcus suis.
5. The method of claim 1 , wherein the method is for conferring protection against an increased mortality associated with a pathogenic infection with Streptococcus suis.
6. The method of claim 1 , wherein the IgM protease antigen is present in an amount below 250 μg per dose of the vaccine, preferably below 120 μg per dose.