Pharmaceutical formulations comprising a pyridylaminoacetic acid compound
Provided is a pharmaceutical preparation for treatment or prevention of glaucoma or ocular hypertension, comprising 0.0003 to 0.01% (w/v) of isopropyl (6-{[4-(pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl)aminomethyl}pyridin-2-ylamino)acetate, or a salt thereof.
1. A liquid pharmaceutical preparation for treatment or prevention of glaucoma or ocular hypertension, comprising 0.001 to 0.003% (w/v) of isopropyl (6-{[4-(pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl) aminomethyl}pyridin-2-ylamino)acetate, or a salt thereof; and water.
2. A liquid pharmaceutical preparation for treatment or prevention of glaucoma or ocular hypertension, comprising 0.002% (w/v) of isopropyl (6-{[4-(pyrazol-1-yl)benzyl](pyridin-3-ylsulfonyl) aminomethyl}pyridin-2-ylamino)acetate, or a salt thereof; and
water.
3. The liquid pharmaceutical preparation according to claim 1 , in which the preparation is for treatment of glaucoma.
4. The liquid pharmaceutical preparation according to claim 1 , in which the preparation is for treatment of ocular hypertension.
5. The liquid pharmaceutical preparation according to claim 1 , in which the preparation does not include other therapeutic agents for glaucoma.
6. The liquid pharmaceutical preparation according to claim 1 , in which the preparation is not used in combination with other therapeutic agents for glaucoma.
7. An eye drop comprising the liquid pharmaceutical preparation of claim 1 .
8. A method for treatment or prevention of glaucoma or ocular hypertension, comprising administrating the liquid pharmaceutical preparation of claim 1 to a patient who needs the treatment or prevention of glaucoma or ocular hypertension.
9. A method for treatment of glaucoma, comprising administrating the liquid pharmaceutical preparation of claim 3 to a patient who needs the treatment of glaucoma.
10. A method for treatment of ocular hypertension, comprising administrating the liquid pharmaceutical preparation of claim 4 to a patient who needs the treatment of ocular hypertension.
11. The method of claim 8 , in which the liquid preparation does not include other therapeutic agents for glaucoma.
12. The method of claim 8 , the liquid preparation is not used in combination with other therapeutic agents for glaucoma.
13. The method of claim 8 , in which the administrating is instillation.
14. The method of claim 13 , in which the instillation is provided once or twice a day.
15. The method of claim 8 , in which a dose of one or two drops is instilled.
16. The method of claim 8 , in which a dose of one drop is instilled once a day.
17. The method of claim 8 , wherein the patient is a human.