IP Library Granted Patent US 11,254,721
Granted Patent B2
US 11,254,721 · App. 16/941,990 · Granted Feb 22, 2022

GIPR-agonist compounds

Inventors: Jorge Alsina-Fernandez (Indianapolis, IN); Andrea Renee Geiser (Greenwood, IN); Lili Guo (Carmel, IN); Samantha Grace Lyons Keyser (Carmel, IN); John Lee (Carmel, IN); Hongchang Qu (Carmel, IN); William Christopher Roell (Avon, IN)
Assignee: Eli Lilly and Company
C07K14/4703A61K38/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,254,721
App. No.
16/941,990
Granted
Feb 22, 2022
Kind
B2
Abstract

The present invention relates to compounds having activity at the human glucose-dependent insulinotropic polypeptide (GIP) receptor. The present invention also relates to compounds having an extended duration of action at the GIP receptor. Such compounds may be useful in the treatment of diabetes, including type 2 diabetes mellitus (“T2DM”). Also, the compounds may be useful in the treatment of obesity.

Claims (3)

1. A compound comprising SEQ ID NO:7, or a pharmaceutically acceptable salt thereof.

2. A method for treating a condition selected from the group consisting of diabetes mellitus, obesity, and metabolic syndrome, comprising administering to a patient in need thereof, an effective amount of a compound, or a pharmaceutically acceptable salt thereof, as claimed by claim 1 .

3. A pharmaceutical composition comprising the compound, or a pharmaceutically acceptable salt thereof, as claimed by claim 1 , and at least one pharmaceutically acceptable carrier, diluent, or excipient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 29, 2020
From: ALSINA-FERNANDEZ, JORGE; GEISER, ANDREA RENEE; GUO, LILI; KEYSER, SAMANTHA GRACE LYONS; LEE, JOHN; QU, HONGCHANG; ROELL, WILLIAM CHRISTOPHER
To: ELI LILLY AND COMPANY
Reel/Frame 053343/0118 →
Continuity (2)
Provisional Application 62881685 · Aug 1, 2019
Related Publication 20210032299A1 · Feb 4, 2021
Cited By (1)
US 12,371,465