Methods, systems, and apparatuses for delivery of electrolysis products
Example apparatuses and systems are disclosed for providing controlled delivery of electrolysis products to a site which may be used for treatment of infection and ablation of undesirable cells and tissue. A system disclosed may include a power supply, two electrodes, an aqueous matrix that may close the electric circuit between the electrodes at the treated site, and a controller. The controller may control the electrical circuit to induce a direct current through the electrodes and an aqueous matrix to produce electrolysis products. The duration and magnitude of the charge applied may determine the dose of the products applied to the treatment site. The composition of the electrodes and the aqueous matrix may be chosen to produce desired products. An apparatus is disclosed that may be in the form of a pad for applying to a wound. An apparatus is disclosed that may be used for treating internal tissue.
1. An apparatus for delivery of electrolysis products to a site, the apparatus comprising:
a first electrode positioned to face a surface external to the apparatus and proximate the site;
a second electrode positioned distal from the surface external to the apparatus; and
an aqueous matrix in contact with at least a first surface and a second surface of the first electrode and configured to be in contact with the surface external to the apparatus, the matrix positioned between the first electrode and the surface external to the apparatus such that the first electrode does not contact the surface external to the apparatus when the apparatus is in use, wherein at least one of the first electrode and second electrode and the aqueous matrix are selected to produce the electrolysis products when a current is passed through the aqueous matrix using at least one of the first electrode and second electrode.
2. The apparatus of claim 1 , wherein the aqueous matrix comprises a gel pad.
3. The apparatus of claim 1 , wherein the aqueous matrix comprises a saline solution.
4. The apparatus of claim 1 , wherein the aqueous matrix has a pH between and including 3 and 5.
5. The apparatus of claim 1 , further comprising a power supply coupled to at least one of the first electrode and second electrode.
6. The apparatus of claim 1 , wherein at least one of the first electrode and second electrode is configured to receive an electronic signal from a controller, wherein the electronic signal is configured for control of at least one of the current or a voltage.
7. The apparatus of claim 6 , wherein the controller is located remotely from at least one of the first electrode and second electrode.
8. The apparatus of claim 6 , wherein the controller is packaged with at least one of the first electrode and second electrode.
9. The apparatus of claim 1 , wherein the aqueous matrix and at least one of the first electrode and second electrode are packaged in a pad configured to adhere to the site.
10. The apparatus of claim 1 , wherein the aqueous matrix and at least one of the first electrode and second electrode are packaged for placement with an implantable device.
11. The apparatus of claim 1 , at least one of the first electrode and second electrode comprises iridium oxide or rubidium oxide.
12. The apparatus of claim 1 , wherein at least one of the first electrode and second electrode is a needle electrode.
13. The apparatus of claim 1 , wherein at least one of the first electrode and second electrode is included in a catheter.
14. The apparatus of claim 1 , wherein at least one of the first electrode and second electrode is a surface electrode.