Model based variable risk false glucose threshold alarm prevention mechanism
Methods of determining when to activate an analyte, e.g. glucose, related alarm, such as a hypoglycemia alarm, of a continuous analyte monitor is provided. Also provided are systems, devices and kits.
1. A method for monitoring an analyte concentration of a user, comprising:
receiving from an analyte sensor measurement data related to a user's analyte concentration, wherein at least a portion of the analyte sensor is transcutaneously positioned in contact with a bodily fluid of the user;
receiving meal intake information of the user by a user input on a display device;
determining the user's analyte concentration using the analyte sensor measurement data;
determining a best-estimate of the user's analyte concentration using the measurement data received from the analyte sensor and the meal intake information of the user;
determining whether the user's analyte concentration and the best-estimate are in agreement;
activating an alarm according to the determination whether the user's analyte concentration and the best-estimate are in agreement, wherein activating the alarm comprises adjusting one or more alarm parameters; and
causing a notification associated with the user's analyte concentration to be displayed on the display device in response to the activating of the alarm.
2. The method of claim 1 , wherein the meal intake information of the user comprises an amount of carbohydrates or an estimate of the amount of carbohydrates.
3. The method of claim 1 , wherein activating the alarm comprises providing a recommendation associated with the user's analyte concentration to the user.
4. The method of claim 3 , wherein providing the recommendation comprises displaying a recommended action for the user to take on a user interface.
5. The method of claim 4 , wherein the recommended action comprises a recommended exercise or diet.
6. The method of claim 3 , wherein the recommendation comprises a bolus of insulin to be delivered to the user.
7. The method of claim 6 , further comprising activating an insulin delivery device to deliver the bolus of insulin to the user.
8. The method of claim 1 , further comprising:
determining a speed or duration of absorption of a meal based on the meal intake information, wherein the best-estimate is determined at least in part based on the determined speed or duration of absorption.
9. The method of claim 8 , wherein the alarm is activated according to a timer selected based on a glucose concentration associated with the speed or duration of absorption of the meal.
10. The method of claim 9 , wherein the determining a glycemic index of a meal from the meal intake information; and
selecting a duration of the timer based at least in part on the glycemic index.
11. The method of claim 1 , wherein the meal intake information comprises a meal time.
12. The method of claim 1 , further comprising determining that when the user's analyte concentration and the best-estimate are in agreement, that an increased likelihood of a glycemic event exists.
13. The method of claim 1 , further comprising selecting the timer corresponding to the user's analyte concentration and the best-estimate.
14. The method of claim 1 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration converges with the best-estimate.
15. The method of claim 1 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration does not diverge from the best-estimate.
16. The method of claim 1 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration and the best-estimate each indicates an abnormal glycemic condition for treatment or analysis.
17. The method of claim 1 , wherein the one or more alarm parameters comprises an alarm delay time.
18. The method of claim 1 , wherein the one or more alarm parameters comprises a threshold value related to the user's analyte concentration.
19. An analyte monitoring system, comprising:
an analyte sensor configured to be partially in contact with bodily fluid under a skin layer of a user to monitor a concentration of an analyte; and
a display device, configured to:
receive measurement data related to the user's concentration of the analyte from the analyte sensor;
receive meal intake information of the user by a user input on the display device;
determine the user's analyte concentration using the measurement data;
determine a best-estimate of the user's analyte concentration using the measurement data received from the analyte sensor and the meal intake information of the user;
determine whether the user's analyte concentration and the best-estimate are in agreement;
activate an alarm according to the determination whether the user's analyte concentration and the best-estimate are in agreement, wherein activating the alarm comprises adjusting one or more alarm parameters; and
cause a notification associated with the user's analyte concentration to be displayed in response to the activation of the alarm.
20. The system of claim 19 , wherein the meal intake information of the user comprises an amount of carbohydrates or an estimate of the amount of carbohydrates.
21. The system of claim 20 , wherein activating the alarm comprises providing a recommendation associated with the user's analyte concentration to the user.
22. The system of claim 21 , wherein providing the recommendation comprises at least displaying a recommended action for the user to take on a user interface of the display device.
23. The system of claim 22 , wherein the recommended action comprises a recommended exercise or diet.
24. The system of claim 19 , wherein the recommendation comprises a bolus of insulin to be delivered to the user.
25. The system of claim 19 , wherein the display device is further configured to:
determine a speed or duration of absorption of a meal based on the meal intake information, wherein the best-estimate is determined in part based on the speed or duration of absorption.
26. The system of claim 25 , wherein the alarm is activated according to a timer selected based on a glucose concentration associated with the speed or duration of absorption of the meal.
27. The system of claim 26 , wherein the determining a glycemic index of a meal from the meal intake information; and
selecting a duration of the timer based at least in part on the glycemic index.
28. The system of claim 19 , wherein the recommendation further comprises activating an insulin delivery device to deliver the bolus of insulin to the user.
29. The system of claim 19 , wherein the meal intake information comprises a meal time.
30. The system of claim 19 , wherein the display device is further configured to determine that when the user's analyte concentration and the best-estimate are in agreement, that an increased likelihood of a glycemic event exists.
31. The system of claim 19 , wherein the display device is further configured to select the timer corresponding to the user's analyte concentration and the best-estimate.
32. The system of claim 19 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration converges with the best-estimate.
33. The system of claim 19 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration does not diverge from the best-estimate.
34. The system of claim 19 , wherein the user's analyte concentration and the best-estimate are in agreement when the user's analyte concentration and the best-estimate each indicates an abnormal glycemic condition for treatment or analysis.
35. The system of claim 19 , wherein the one or more alarm parameters comprises an alarm delay time.
36. The system of claim 19 , wherein the one or more alarm parameters comprises a threshold value related to the user's analyte concentration.