IP Library Granted Patent US 11,449,985
Granted Patent B2
US 11,449,985 · App. 15/829,562 · Granted Sep 20, 2022

Computer vision for cancerous tissue recognition

Inventors: Panagiotis Stanitsas (Palo Alto, CA); Anoop Cherian (Belmont, MA); Vassilios Morellas (Plymouth, MN); Nikolaos Papanikolopoulos (Minneapolis, MN); Alexander Truskinovsky (Williamsville, NY)
Assignees: Regents of the University of Minnesota; Australian National University
G06T7/0012G06F3/04842G06F3/04847G06T5/40G06T17/10G06T2207/10024G06T2207/10056G06T2207/20021G06T2207/20076G06T2207/20081G06T2207/20104G06T2207/30024G06T2207/30028G06T2207/30061G06T2207/30081G06T2207/30096
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Quick Facts
Patent No.
US 11,449,985
App. No.
15/829,562
Granted
Sep 20, 2022
Kind
B2
Abstract

A system includes an imager, a processor, and an output module. The imager is configured to provide a plurality of tissue images. The processor is coupled to the imager and is configured to receive the plurality of images. The processor is coupled to a memory. The memory has instructions for determining classification of a region of tissue associated with the plurality of tissue images. Determining classification includes fusing discriminator outputs from a region covariance descriptor and from a normalized color histogram discriminator. The output module is coupled to the processor. The output module is configured to provide a three dimensional representation of the tissue.

Claims (14)

1. A system comprising:

an imager configured to provide a plurality of histopathological images for a region of a tissue sample;

a processor coupled to the imager and configured to receive the plurality of histopathological images, the processor coupled to a memory, the memory having instructions for determining classification of the region of tissue associated with the plurality of histopathological images, wherein determining classification includes fusing discriminator outputs from a region covariance descriptor and from a normalized color histogram discriminator; and

an output module coupled to the processor, the output, module configured to provide a three dimensional representation of the region of the tissue.

2. The system of claim 1 wherein the processor is configured to fuse discriminator output from the region covariance descriptor with a positive definite kernel matrix generated from color histograms.

3. The system of claim 1 wherein the processor is configured to receive an output from the normalized color histogram discriminator corresponds to a normalized histogram.

4. The system of claim 1 wherein the processor is configured to receive an output from the region covariance descriptor in which the region covariance descriptor provides covariance matrix of five dimensions.

5. The system of claim 1 wherein the processor is configured to determine a classification based on a sparse code and a dictionary matrix.

6. The system of claim 1 wherein the processor is configured to determine a classification based on at least one of a bank of Gabor filters, a histogram of oriented gradients, a plurality of Fisher vectors, and a convoluted neural network model.

7. The system of claim 1 wherein the processor is configured to determine a classification based on a covariance-kernel descriptor.

8. The system of claim 7 wherein the processor is configured to determine a classification based on a bag of visual words representation and based on scale invariant feature transform descriptors.

9. The system of claim 1 wherein the imager includes a graphical user interface.

10. The system of claim 9 wherein the graphical user interface is configured to allow user selection of magnification of an image.

11. The system of claim 9 wherein the graphical user interface is configured to allow user selection of the region.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2022
From: CHERIAN, ANOOP
To: AUSTRALIAN NATIONAL UNIVERSITY
Reel/Frame 060317/0325 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2021
From: STANITSAS, PANAGIOTIS; MORELLAS, VASSILIOS; PAPANIKOLOPOULOS, NIKOLAOS; TRUSKINOVSKY, ALEXANDER
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 055119/0598 →
CONFIRMATORY LICENSE Recorded Feb 16, 2018
From: UNIVERSITY OF MINNESOTA
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 045356/0274 →
Continuity (2)
Provisional Application 62429353 · Dec 2, 2016
Related Publication 20180165809A1 · Jun 14, 2018
Cited By (3)
US 12,392,884 US 12,399,266 US 12,548,356