Determination of cardiac parameters for modulation of blood pump support
The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and/or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.
1. A method for providing cardiac support to a heart, comprising:
operating a blood pump positioned in the heart, the blood pump having a cannula and including a motor operating at a motor speed and a drawing a variable motor current to provide a level of cardiac support to the heart;
measuring at a controller coupled to the blood pump, an aortic pressure;
measuring, at the controller, the motor current;
determining a pressure gradient across the cannula associated with the motor current;
using a processor to calculate, from the aortic pressure and the pressure gradient across the cannula associated with the motor current, a calculated cardiac parameter;
recording, in a memory, the calculated cardiac parameter;
determining, based on the calculated cardiac parameter, a heart function parameter;
determining, based on the calculated cardiac parameter and the heart function parameter, a problem with a positioning of the blood pump; and
displaying a warning.
2. The method of claim 1 , wherein the blood pump is positioned in an aortic valve of the heart, and wherein the method further comprises determining a distance from a distal end of the blood pump to a feature of the heart.
3. The method of claim 2 , the method further comprising displaying a recommendation for repositioning the blood pump.
4. The method of claim 3 , the method further comprising displaying the distance from the distal end of the blood pump to the feature of the heart.
5. The method of claim 1 , wherein the problem with a positioning of the blood pump is a suction event.
6. The method of claim 1 , wherein the cardiac parameter is a left ventricular pressure.
7. The method of claim 1 , wherein displaying the warning comprises displaying the warning on an interface touch screen, and wherein the method further comprising actuating the interface touch screen based on at least one of the calculated cardiac parameter and the heart function parameter.
8. The method of claim 1 , wherein a left ventricular pressure is displayed as a waveform in real time.
9. The method of claim 1 , wherein the blood pump is positioned in a left ventricle.
10. The method of claim 1 , wherein determining the pressure gradient across the cannula associated with the motor current comprises accessing a look-up table.
11. The method of claim 1 , the method further comprising:
using the processor to calculate, from the aortic pressure and the pressure gradient across the cannula, a left ventricular pressure and a cardiac power output;
determining, based on the calculated left ventricular pressure and the calculated cardiac power output, a recommended adjustment to the motor speed; and
displaying the recommended adjustment to the motor speed on a display.
12. The method of claim 11 , the method further comprising displaying a recommendation to increase the motor speed based on the calculated left ventricular pressure and the calculated cardiac power output.
13. The method of claim 11 , the method further comprising displaying a recommendation to decrease the motor speed based on the calculated left ventricular pressure and the calculated cardiac power output.
14. The method of claim 11 , the method further comprising:
using the processor to compare the calculated left ventricular pressure to a previous left ventricular pressure; and
using the processor to compare the calculated cardiac power output to a previous cardiac power output.
15. The method of claim 14 , wherein if the calculated left ventricular pressure increases from the previous left ventricular pressure and if the calculated cardiac power output decreases from a previous cardiac power output the method comprises displaying a recommendation to adjust the motor speed.
16. The method of claim 14 , wherein if the calculated left ventricular pressure decreases from the previous left ventricular pressure and if the calculated cardiac power output increases from a previous cardiac power output the method comprises displaying a recommendation to adjust the motor speed.
17. The method of claim 1 , wherein the calculated cardiac parameter includes at least one of a left ventricular pressure, a left ventricular end diastolic pressure, a pressure differential across the cannula of the blood pump, a blood pump flow rate, a native cardiac output, a total cardiac output, a native cardiac power output, and a total cardiac power output.
18. The method of claim 1 , wherein the heart function parameter includes one of a cardiac contractility value, a cardiac relaxation value, a fluid responsiveness value, a cardiac output measure, a left ventricular diastolic dysfunction measurement, a left ventricular systolic and diastolic elastance.
19. The method of claim 18 , wherein the blood pump is a right-side heart device.