Method of using nebulized alcohol for analgesia

1. A method, comprising:

measuring a patient pain level prior to delivering a dose of analgesic compound to the patient;

determining a number of inhalation periods in which to deliver the dose of analgesic compound to the patient;

delivering the dose of analgesic compound to the patient by inhalation by the patient from an active mesh nebulizer at a regular interval, wherein delivering the dose of analgesic compound to the patient is delayed by 1 to 3 seconds after the patient initiates inhalation;

measuring the patient pain level after delivering the dose of analgesic compound to the patient; and

determining whether to repeat delivering the dose of analgesic compound to the patient, wherein

the dose of analgesic compound comprises a dose of ethanol,

the dose of analgesic compound delivered by inhalation from the active mesh nebulizer further comprises particles having a diameter of not less than 0.5 μm and not greater than 5 μm, and wherein

delivering the dose of analgesic compound to the patient begins to provide pain relief within about 10 seconds.

2. The method of claim 1 , wherein delivering the dose of ethanol to the patient by inhalation from an active mesh nebulizer at a regular interval further comprises:

generating a plume of particles of an ethanol solution in the active mesh nebulizer after the start of a patient inhalation; and

stopping generating the plume of particles of the ethanol solution before the end of the patient inhalation.

3. The method of claim 2 , further comprising:

calculating a vibrational time for the active mesh of the active mesh nebulizer to generate the dose of ethanol based on an active mesh nebulizer nebulization rate, an alcohol concentration in the ethanol solution, and the dose of ethanol.

4. The method of claim 3 , further comprising monitoring the vibrational time of the active mesh and preventing the active mesh from vibrating upon reaching the calculated vibrational time to generate the dose of ethanol.

5. The method of claim 1 , further comprising:

evaluating the patient for symptoms of alcohol intolerance subsequent to delivering the dose of ethanol to the patient by inhalation from the active mesh nebulizer.

6. The method of claim 5 , further comprising:

determining the dose of ethanol by delivering at least one incremental dose of ethanol from the active mesh nebulizer until the patient exhibits symptoms of alcohol intolerance.

7. The method of claim 6 , wherein the dose is the at least one incremental dose of ethanol multiplied by a scaling factor ranging from 0.5 to 0.8.

8. The method of claim 1 , further comprising determining whether to change the dose of ethanol delivered by inhalation from the active mesh nebulizer.

9. A method, comprising:

measuring a patient pain level;

determining a first dose of ethanol by scaling a cumulative dose of ethanol;

delivering the first dose of ethanol to a patient by inhalation from an active mesh nebulizer at a repeated interval;

evaluating the patient pain level after delivering the first dose of ethanol to the patient by inhalation from the active mesh nebulizer at a repeated interval;

determining whether to replace the first dose of ethanol with a second dose of ethanol different from the first dose of ethanol; and

delivering the second dose of ethanol to a patient by inhalation from the active mesh nebulizer at the repeated interval, wherein delivering a dose of ethanol to a patient by inhalation from an active mesh nebulizer further comprises delivering droplets of ethanol solution having a diameter of not less than 0.5 μm and not greater than 5 μm, wherein each of delivering the first dose of ethanol and delivering the second dose of ethanol begins to provide an analgesic effect within about 10 seconds from delivering the dose of ethanol.

10. The method of claim 9 , further comprising:

determining, subsequent to delivering the second dose of ethanol to the patient by inhalation from the active mesh nebulizer at the repeated interval, whether to replace the second dose of ethanol with a third dose of ethanol, wherein the third dose of ethanol is larger than the second dose of ethanol.

11. The method of claim 9 , further comprising:

determining, for a patient taking a non-alcohol pain medication, whether to adjust a first dose of the non-alcohol pain medication while continuing to deliver the second dose of ethanol at the repeated interval to the patient taking the non-alcohol pain medication.

12. The method of claim 11 , further comprising:

replacing the first dose of the non-alcohol pain medication with a second dose of the non-alcohol pain medication and continuing to deliver the second dose of ethanol to the patient by inhalation from the active mesh nebulizer at the repeated interval.

13. A method of reducing patient pain, comprising:

determining a degree of patient pain in a patient;

delivering a dose of analgesic compound to the patient, wherein the analgesic compound further comprises ethanol, and wherein delivering the dose of analgesic compound further comprises delivering the ethanol to the patient from an active mesh nebulizer at a regular interval after determining the degree of patient pain in the patient, wherein delivering the dose of analgesic compound begins to provide an analgesic effect within about 10 seconds from delivering the dose of analgesic compound;

measuring the degree of patient pain after delivering the dose of analgesic compound to the patient from the active mesh nebulizer; and

determining whether to repeat delivering the dose of analgesic compound to the patient from the active mesh nebulizer.

14. The method of claim 13 , wherein delivering a dose of analgesic compound to the patient from the active mesh nebulizer at a regular interval further comprises:

generating a plume of particles of an ethanol solution in the active mesh nebulizer; and

inhaling the plume of particles of the ethanol solution.

15. The method of claim 14 , wherein generating a plume of particles of an ethanol solution further comprises generating a plume of particles, wherein at least 80% of the particles have a particle diameter of at least 0.5 micrometers (μm) and not more than 5.0 μm.

16. The method of claim 14 , wherein delivering the dose of analgesic compound to the patient from the active mesh nebulizer at a regular interval further comprises delivering the dose of analgesic compound at a regular interval of not more than 12 hours.

17. The method of claim 13 , further comprising

evaluating the degree of patient pain after delivering the dose of analgesic compound; and

determining whether to modify the dose of analgesic compound in response to evaluating the degree of patient pain.

18. The method of claim 17 , further comprising:

delivering a dose of non-alcohol pain medication to the patient; and

determining, for a patient taking the non-alcohol pain medication after delivering the dose of analgesic compound from the active mesh nebulizer, whether to adjust a dose of the non-alcohol pain medication while continuing to deliver the dose of analgesic compound at the regular interval to the patient taking the non-alcohol pain medication.

19. The method of claim 18 , further comprising adjusting the dose of the non-alcohol pain medication in response to determining whether to adjust the dose of the non-alcohol pain medication.

20. The method of claim 17 , further comprising monitoring the dose of analgesic compound delivered from the active mesh nebulizer by monitoring a duration of vibrational time for the active mesh in the active mesh nebulizer.