All-trans polyene amphoteric macrolide
The present invention is directed to a process for purifying natamycin, to an all-trans polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.
1. A compound comprising (1R,3S,5E,7R,11R,13E,15E,17E,19E,21R,23S,24R,25S)-21-[(3-Amino-3,6-dideoxy-β- D -mannopyranosyl)oxy]-1,3,7,25-tetrahydroxy-11-methyl-9-oxo-10,27-dioxabicyclo-[21.3.1]heptacosa-5,13,15,17,19-pentaene-24-carboxylic acid of formula (II) or a salt thereof
2. A composition comprising natamycin, water and the compound or salt according to claim 1 wherein the amount of water is from 0.001-10% (w/w) and wherein the amount of said compound or salt according to claim 1 is from 0.001-0.1% (w/w) relative to the amount of natamycin.