IP Library Granted Patent US 11,639,722
Granted Patent B2
US 11,639,722 · App. 17/135,425 · Granted May 2, 2023

Pressure/flow characteristic modification of a centrifugal pump in a ventricular assist device

Inventors: Alexander Medvedev (Ann Arbor, MI); Muhammad Sami (Ypsilanti, MI)
Assignee: TC1 LLC
F04D15/0066A61M60/148A61M60/178A61M60/232A61M60/411A61M60/546A61M60/585F04D13/06F04D15/0088F04D29/22A61M2205/3334F05D2270/3061
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Quick Facts
Patent No.
US 11,639,722
App. No.
17/135,425
Granted
May 2, 2023
Kind
B2
Abstract

A ventricular assist device is disclosed. The ventricular assist device may include a centrifugal pump and a controller. The controller may be configured to cause the centrifugal pump to operate at a first speed above a predetermined flow rate. The controller may also be configured to cause the centrifugal pump to operate at a second speed below the predetermined flow rate, wherein the predetermined flowrate is indicative of a crossover point between systole and diastole phases of a person's cardiac cycle.

Claims (41)

1. A ventricular assist device, comprising:

a centrifugal pump comprising a motor; and

at least one processor configured to:

determine a flow rate through the centrifugal pump based on a current of the motor;

cause the motor to operate at a first speed when the flow rate is greater than a predetermined flow rate during a systolic phase, wherein the predetermined flow rate corresponds with a flow rate indicative of a crossover point between the systolic phase and a diastolic phase, wherein when the motor operates at the first speed, the motor is operating a variable current; and

cause the motor to operate at a second speed when the flow rate is less than the predetermined flow rate during the diastolic phase, wherein when the motor operates at the second speed, the motor is operating at one or both of a constant current and a constant speed.

2. The ventricular assist device of claim 1 , wherein:

pressure generated by the centrifugal pump is increased during a diastolic phase.

3. The ventricular assist device of claim 1 , wherein:

the second speed is greater than the first speed.

4. The ventricular assist device of claim 1 , wherein:

the predetermined flowrate is set by a clinician.

5. The ventricular assist device of claim 1 , further comprising:

a flow measurement sensor, wherein the flow rate is determined based on a measurement from the flow measurement sensor.

6. The ventricular assist device of claim 1 , wherein:

the at least one processor is further configured to:

detect a suction event in the centrifugal pump; and

reduce a speed of the centrifugal pump to alleviate the suction event.

7. A method of controlling a ventricular assist device, comprising:

determining a flow rate through a centrifugal pump of the ventricular assist device based on a current of a motor of the centrifugal pump;

causing a motor of the centrifugal pump to operate at a first speed when the flow rate is greater than a predetermined flow rate during a systolic phase, wherein the predetermined flow rate corresponds with a flow rate indicative of a crossover point between the systolic phase and a diastolic phase, wherein when the motor operates at the first speed, the motor is operating a variable current; and

causing the motor to operate at a second speed when the flow rate is less than the predetermined flow rate during the diastolic phase, wherein when the motor operates at the second speed, the motor is operating at one or both of a constant current and a constant speed.

8. The method of controlling a ventricular assist device of claim 7 , wherein:

the first speed is a minimum operating speed of the centrifugal pump.

9. The method of controlling a ventricular assist device of claim 7 , wherein:

the first speed is input by a clinician.

10. The method of controlling a ventricular assist device of claim 7 , further comprising:

detecting a suction event in the centrifugal pump; and

reducing a speed of the centrifugal pump to alleviate the suction event.

11. The method of controlling a ventricular assist device of claim 7 , wherein:

pressure generated by the centrifugal pump is increased during a diastolic phase.

12. A non-transitory machine readable medium having instructions stored thereon, wherein the instructions, when executed, cause at least one processor to perform operations comprising:

determining a flow rate through a centrifugal pump of a ventricular assist device;

causing a motor of the centrifugal pump to operate at a first speed when the flow rate is greater than a predetermined flow rate during a systolic phase, wherein the predetermined flow rate corresponds with a flow rate indicative of a crossover point between the systolic phase and a diastolic phase, wherein when the motor operates at the first speed, the motor is operating a variable current;

causing the motor to operate at a second speed when the flow rate is less than the predetermined flow rate during the diastolic phase, wherein when the motor operates at the second speed, the motor is operating at one or both of a constant current and a constant speed;

detecting a suction event in the centrifugal pump; and

reducing a speed of the centrifugal pump to alleviate the suction event.

13. The non-transitory machine readable medium of claim 12 , wherein:

the first speed is within 10% of a clinician set speed.

14. The non-transitory machine readable medium of claim 12 , wherein:

the motor maintains one or more of a constant back electromotive force (emf), a constant left ventricular pressure, a constant pulmonic pressure, and a constant aortic pressure.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 12, 2022
From: MEDVEDEV, ALEXANDER; SAMI, MUHAMMAD
To: THORATEC CORPORATION
Reel/Frame 060487/0259 →
CHANGE OF NAME Recorded Jul 12, 2022
From: THORATEC CORPORATION
To: THORATEC LLC
Reel/Frame 060637/0202 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 12, 2022
From: THORATEC LLC
To: TC1 LLC
Reel/Frame 060637/0304 →
Continuity (4)
Continuation 16173589 · Oct 29, 2018
Continuation 15352141 · Nov 15, 2016
Provisional Application 62255774 · Nov 16, 2015
Related Publication 20210113828A1 · Apr 22, 2021
Cited By (27)
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