IP Library Granted Patent US 11,660,313
Granted Patent B2
US 11,660,313 · App. 17/139,268 · Granted May 30, 2023

Compositions and methods for application over skin

Inventors: Ariya Akthakul (Boston, MA); Nithin Ramadurai (Wakefield, MA); Amir Nashat (Boston, MA); Daniela Beccati (Watertown, MA); Melaney Bouthillette (Newton, MA)
Assignee: Shiseido Company, Limited
A61K31/80A61K9/0014A61K9/7015A61K31/573A61K31/58A61L26/0019A61L26/0061
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Quick Facts
Patent No.
US 11,660,313
App. No.
17/139,268
Granted
May 30, 2023
Kind
B2
Abstract

Disclosed herein are compositions that can form a covering, layer, film, device, and/or prosthetic skin that can be comfortably worn to provide skin barrier function, skin hydration and therapeutic and aesthetic benefits. The present invention provides novel compositions that have low tackiness and form quickly, resulting in a wearable, comfortable (maintains temperature and humidity), breathable, thin, optically invisible, cosmetically elegant, flexible, stretchable, elastic and body-movement conforming, yet long-lasting covering, layer, film, device, and/or prosthetic skin on the skin or any other body surface. The present invention provides novel compositions that can form a covering, layer, film, device, and/or prosthetic skin that works for extended periods in excess of about 24 hours, while retaining function during and after exercising, showering and swimming (in sea-water, fresh water and chlorinated water), steam room (heat at high humidity), and sauna (heat at low humidity).

Claims (22)

1. A composition for the in-situ formation of a layer over the skin of a subject,

wherein

the composition is a two-part composition comprising a first part and a second part;

the first part comprises Polymer A and Polymer B;

the second part comprises a catalyst;

Polymer A comprises one or more organopolysiloxane(s) having on average at least two alkenyl-functional groups and having a viscosity of about 10,000 to about 2,000,000 cSt at about 25° C.;

Polymer B comprises one or more organopolysiloxane(s) having on average at least two Si—H units and having a viscosity of about 2 to about 500,000 cSt at about 25° C.;

the catalyst facilitates crosslinking of Polymer A and Polymer B; and

wherein the first part or the second part further comprises a reinforcing component selected from the group consisting of surface-treated carbon or graphene.

2. The composition of claim 1 ,

wherein the first part or the second part further comprises about 0.001% to about 25% by weight of graphene.

3. The composition of claim 1 , wherein the second part further comprises Polymer C; and Polymer C comprises one or more organopolysiloxane(s) having on average at least one alkenyl-functional groups and having a viscosity of about 0.7 cSt to about 10,000 cSt at about 25° C.

4. The composition of claim 1 ,

wherein the first part comprises about 5% to about 90% by weight of Polymer A; about 5% to about 75% by weight of Polymer B.

5. The composition of claim 1 ,

wherein the first part comprises about 5% to about 90% by weight of Polymer A; about 5% to about 30% by weight of Polymer B; and about 0.001% to about 25% by weight of the reinforcing component.

6. The composition of claim 1 ,

wherein the second part comprises as ingredients about 0.001% to about 1% by weight one or more catalyst(s).

7. The composition of claim 1 ,

wherein the second part comprises as ingredients about 0.005% to about 0.05% by weight one or more catalyst(s).

8. A kit comprising the composition of claim 1 , further comprising instructions for use, a cleanser suitable for removing said layer from the skin or one or more brush(es), swab(s), and/or mirror(s).

9. A method for modifying skin function, wherein the method comprises applying the composition of claim 1 to the subject in need thereof.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2021
From: AKTHAKUL, ARIYA; RAMADURAI, NITHIN; NASHAT, AMIR; BECCATI, DANIELA; BOUTHILLETTE, MELANEY
To: OLIVO LABORATORIES, LLC
Reel/Frame 055689/0113 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2021
From: OLIVO LABORATORIES, LLC
To: SHISEIDO AMERICAS CORPORATION
Reel/Frame 055689/0215 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2021
From: SHISEIDO AMERICAS CORPORATION
To: SHISEIDO COMPANY, LIMITED
Reel/Frame 055689/0309 →
Continuity (3)
Continuation 15774350
Provisional Application 62252903 · Nov 9, 2015
Related Publication 20210213046A1 · Jul 15, 2021