IP Library › Granted Patent US 11,728,035
Granted Patent B1
US 11,728,035 · App. 17/888,432 · Granted Aug 15, 2023

Radiologist assisted machine learning

Inventors: Robert Edwin Douglas (Winter Park, FL); David Byron Douglas (Winter Park, FL); Kathleen Mary Douglas (Winter Park, FL)
G16H50/20G16H30/20
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Quick Facts
Patent No.
US 11,728,035
App. No.
17/888,432
Granted
Aug 15, 2023
Kind
B1
Abstract

A computerized medical diagnostic system uses a training dataset that is updated based on reports generated by a radiologist. AI and/or CAD is used to make an initial determination of no finding, finding, or diagnosis based on the training dataset. Normal results with a high confidence of no finding are not reviewed by the radiologist. Low confidence results, findings, and diagnosis are reviewed by the radiologist. The radiologist generates a report that associates terminology and weighting with marked 3D image volumes. The report is used to update the training dataset.

Claims (38)

1. A method comprising:

continuously updating a training dataset while analyzing medical image data with a medical image diagnostic computer having machine-learning capability, comprising the steps of:

using a medical image comprising a CT scan, a MRI scan, a PET scan, an ultrasound or a SPECT scan wherein said medical image comprises a first number of voxels;

using a segmentation algorithm to segment a structure within said medical image wherein said structure comprises a second number of voxels

wherein said second number of voxels is less than said first number of voxels, and

wherein said structure comprises multiple voxels corresponding to a sub-volume of said medical image,

wherein the selected sub-volume corresponds to an item on a diagnostic checklist;

analyzing the selected sub-volume to create a human-generated analysis; and

using the human-generated analysis of the sub-volume to update the training dataset.

2. The method of claim 1 comprising analyzing the selected sub-volume using the training dataset to create a machine-generated analysis with the diagnostic computer before manually analyzing the selected sub-volume.

3. The method of claim 2 comprising resolving disagreement between the human-generated analysis and the machine-generated analysis before using the human-generated analysis to update the training dataset.

4. The method of claim 3 comprising generating a computer-made explanation for the machine-generated analysis.

5. The method of claim 4 comprising updating the human-generated analysis based on the explanation before using the human-generated analysis to update the training dataset.

6. The method of claim 3 comprising prompting a consensus review of the human-generated analysis and machine-generated analysis.

7. The method of claim 6 comprising updating the human-generated analysis based on the consensus review before using the human-generated analysis to update the training dataset.

8. The method of claim 1 comprising the diagnostic computer retrieving and presenting patient-specific data pertinent to the item on the checklist to facilitate creation of the human-generated analysis.

9. The method of claim 1 wherein creating the human-generated analysis comprises creating at least one of: terminology describing findings or diagnosis; marked pixels or voxels; and an indication of certainty of the findings or diagnosis.

10. The method of claim 1 wherein creating the machine-generated analysis comprises creating at least one of: terminology describing findings or diagnosis; marked pixels or voxels; and an indication of certainty of the findings or diagnosis.

11. The method of claim 1 comprising filtering out tissue within the selected sub-volume that is not associated with a finding.

12. The method of claim 1 comprising using a three-dimensional cursor to select said segmented structure.

13. The method of claim 11 comprising automatically re-sizing the three-dimensional cursor to encompass tissue associated with the finding.

14. The method of claim 3 wherein the checklist comprises multiple items, each of which is analyzed, and comprising generating a report based on the human-generated analysis.

15. The method of claim 14 comprising including an indication of disagreement between the human-generated analysis and the machine-generated analysis.

16. The method of claim 1 comprising the three-dimensional cursor visually indicating confidence or dangerousness of a diagnosis.

17. The method of claim 1 comprising placing tissue associated with a finding in a virtual container.

18. The method of claim 17 comprising selecting a virtual container from a normal finding container, a disease-specific container, and differential diagnosis container.

19. An apparatus comprising:

a medical image diagnostic computer having machine-learning capability, the diagnostic computer comprising a non-transitory medium on which is stored computer program logic that continuously updates a training dataset while analyzing medical image data, comprising:

item selection logic that selects a sub-volume of a medical image corresponding to a structure by using a segmentation algorithm to segment said structure,

wherein the selected sub-volume corresponds to an item on a diagnostic checklist,

wherein said medical image comprises a CT scan, a MM scan, a PET scan, an ultrasound or a SPECT scan,

wherein said medical image comprises a first number of voxels,

wherein said structure comprises multiple voxels corresponding to said sub-volume of said medical image,

wherein said structure comprises a second number of voxels, and

wherein said second number of voxels is less than said first number of voxels;

input logic that receives input that creates a human-generated analysis of the selected sub-volume; and

update logic that updates the training dataset based on the human-generated analysis.

20. The apparatus of claim 19 comprising diagnostic logic that analyzes the selected sub-volume using the training dataset to create a machine-generated analysis before the human-generated analysis is generated.

Continuity (9)
Continuation 16939192
Continuation In Part 16843988 · Apr 9, 2020
Continuation In Part 16752662 · Jan 26, 2020
Continuation In Part 16195251 · Nov 19, 2018
Continuation In Part 15904092 · Feb 23, 2018
Provisional Application 62748555 · Oct 22, 2018
Provisional Application 62695868 · Jul 10, 2018
Provisional Application 62651934 · Apr 3, 2018
Provisional Application 62628527 · Feb 9, 2018
Cited By (1)
US 12,288,326