IP Library Granted Patent US 11,752,149
Granted Patent B2
US 11,752,149 · App. 17/103,455 · Granted Sep 12, 2023

Muscarinic acetylcholine M1 receptor antagonists

Inventors: Yifeng Xiong (San Diego, CA); Jeffrey Roppe (Temecula, CA); Austin Chih-Yu Chen (San Diego, CA); Yalda Bravo (San Diego, CA); Thomas Schrader (San Diego, CA); Jill Melissa Baccei (San Diego, CA)
Assignee: Pipeline Therapeutics, Inc.
A61K31/4995A61K31/501A61K45/06C07D487/08
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Quick Facts
Patent No.
US 11,752,149
App. No.
17/103,455
Granted
Sep 12, 2023
Kind
B2
Abstract

Provided herein are compounds which are useful as antagonists of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.

Claims (3)

1. A compound selected from:

or a pharmaceutically acceptable salt or solvate thereof.

2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt or solvate thereof, and at least one pharmaceutically acceptable excipient.

Assignments (2)
CHANGE OF NAME Recorded Jan 18, 2024
From: PIPELINE THERAPEUTICS, INC.
To: CONTINEUM THERAPEUTICS, INC.
Reel/Frame 066353/0070 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 31, 2021
From: XIONG, YIFENG; ROPPE, JEFFREY; CHEN, AUSTIN CHIH-YU; BRAVO, YALDA; SCHRADER, THOMAS; BACCEI, JILL MELISSA
To: PIPELINE THERAPEUTICS, INC.
Reel/Frame 055787/0084 →
Continuity (2)
Provisional Application 62942665 · Dec 2, 2019
Related Publication 20210161889A1 · Jun 3, 2021
Cited By (2)
US 12,390,462 US 12,565,501