Compositions and methods of enhancing immune responses
View Patent ↗A vaccine vector comprising a first polynucleotide encoding the antigenic polypeptide selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, or any combination thereof.
1. A vaccine vector comprising:
a polynucleotide encoding the antigenic polypeptide selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, or any combination thereof.
2. The vaccine vector of claim 1 wherein the vaccine vector is a bacterium.
3. The vaccine vector of claim 2 , wherein the bacterial vaccine vector is a Bacillus spp.
4. The vaccine vector of claim 1 further comprising one or more immunostimulatory polypeptides.
5. The vaccine vector of claim 1 wherein the antigenic polypeptide is present on the surface of the vaccine vector.
6. A pharmaceutical composition comprising the vaccine vector of claim 1 and a pharmaceutically acceptable carrier.