8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid as an antioxidant compound
An 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound, its synthesis, and its use as an antioxidant agent.
1. An 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound having the formula I:
2. A pharmaceutically acceptable composition comprising a therapeutically effective amount of the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 1 and a pharmaceutically acceptable carrier.
3. A method of making the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 1 , the method comprising:
mixing 8-aminonaphthalene-1,3-disulfonic acid, 4-chlorobenzaldehyde, and triethylamine (TEA) in ethanol to obtain a solution;
irradiating the solution followed by cooling to room temperature to obtain a formed precipitate;
purifying the formed precipitate by filtering and recrystallization using ethanol; and
obtaining the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound.
4. The method of making the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 3 , wherein the irradiating the solution takes place in a sonicator for at least about 2 hours.
5. The method of making the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 3 , wherein the irradiating the solution is conducted at about 50° C.
6. The method of making the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 3 , wherein the purifying the formed precipitate includes collecting the formed precipitate by filtration and washing the formed precipitate with distilled water.
7. The method of making the 8-(4-chlorobenzylideneamino)naphthalene-1,3-disulfonic acid compound of claim 3 , wherein the 8-aminonaphthalene-1,3-disulfonic acid and the 4-chlorobenzaldehyde are added in about a 1:1 molar ratio.