IP Library Granted Patent US 12,018,262
Granted Patent B2
US 12,018,262 · App. 17/288,530 · Granted Jun 25, 2024

Method for producing washing enzyme having protease resistance

Inventors: Qing Zhang (Shandong, CN); Zhibing Chen (Shandong, CN); Yanping Liu (Shandong, CN); Yanjun Tian (Shandong, CN); Wei Xu (Shandong, CN); Yinan Guan (Shandong, CN); Yijun Huang (Shandong, CN); Jiahua Lyu (Shandong, CN)
Assignee: QINGDAO VLAND BIOTECH GROUP CO., LTD
C12N15/62C07K14/811C12N9/20C12N9/2437C12N9/96
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Quick Facts
Patent No.
US 12,018,262
App. No.
17/288,530
Granted
Jun 25, 2024
Kind
B2
Abstract

Provided is a method for producing washing enzyme having protease resistance. According to the method, the washing enzyme having resistance to protease is obtained by carrying out fusion expression on a gene of the washing enzyme with the gene of a protease inhibitory peptide, thereby facilitating maintaining the stability of various enzyme components in an enzyme-containing detergent, and improving the use effect of the detergent.

Claims (8)

1. A laundry enzyme with protease resistance, which is a fusion protein of a laundry enzyme and a protease inhibitory peptide; wherein the laundry enzyme is selected from the group consisting of cellulase, lipase, cutinase, amylase, glucoamylase, pectinase, mannanase, arabinase, galactosidase, xylanase, laccase and peroxidase; and

the protease inhibitory peptide is selected from the group consisting of Streptomyces subtilisin inhibitor (SSI) from Streptomyces sp., protease inhibitory peptide PCL from Barley, protease inhibitor marinostatin (MST) from Alteromonas , and a mixture thereof.

2. The laundry enzyme with protease resistance according to claim 1 , wherein the laundry enzyme and the protease inhibitory peptide of the fusion protein are fused covalently.

3. The laundry enzyme with protease resistance according to claim 1 , wherein the laundry enzyme is cellulase or lipase, and the protease inhibitory peptide is selected from the group consisting of Streptomyces subtilisin inhibitor (SSI) from Streptomyces sp., protease inhibitory peptide PCL from Barley, and protease inhibitor marinostatin (MST) from Alteromonas.

4. The laundry enzyme with protease resistance according to claim 3 , wherein the laundry enzyme is cellulase, and the protease inhibitory peptide is selected from the group consisting of protease inhibitory peptide PCL from Barley, and protease inhibitor marinostatin (MST) from Alteromonas.

5. The laundry enzyme with protease resistance according to claim 1 , wherein the laundry enzyme is cellulase.

6. The laundry enzyme with protease resistance according to claim 1 , wherein the laundry enzyme is lipase.

7. The laundry enzyme with protease resistance according to claim 1 , wherein the protease inhibitory peptide is fused to the laundry enzyme in N-terminus, C-terminus or middle.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2021
From: ZHANG, QING; CHEN, ZHIBING; LIU, YANPING; TIAN, YANJUN; XU, WEI; GUAN, YINAN; HUANG, YIJUN; LYU, JIAHUA
To: QINGDAO VLAND BIOTECH GROUP CO., LTD
Reel/Frame 056029/0777 →
Priority Claims (1)
CN 201811285860.9 · Oct 31, 2018 · national
Continuity (1)
Related Publication 20220010315A1 · Jan 13, 2022