IP Library › Granted Patent US 12,180,170
Granted Patent B1
US 12,180,170 · App. 18/425,970 · Granted Dec 31, 2024

2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid as an antimicrobial compound

Inventors: Hany Mohamed Abd El-Lateef Ahmed (Al-Ahsa, SA); Mai Mostafa Khalaf Ali (Al-Ahsa, SA); Antar Ahmed Abdelhamid Ahmed (Sohag, EG); Amer A. Amer (Sohag, EG)
Assignee: KING FAISAL UNIVERSITY
C07D249/08A61P31/04A61P31/10
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Quick Facts
Patent No.
US 12,180,170
App. No.
18/425,970
Granted
Dec 31, 2024
Kind
B1
Abstract

An 2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid compound, its synthesis, and its use as an antimicrobial agent.

Claims (6)

1. A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of a 2-(5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)acetic acid compound having the formula I:

2. The method of treating the microbial infection of claim 1 , wherein the microbial infection is caused by one or more bacteria or fungi.

3. The method of treating the microbial infection of claim 2 , wherein the microbial infection is caused by one or more gram positive bacteria, one or more gram negative bacteria, one or more fungi, or a combination thereof.

4. The method of treating the microbial infection of claim 3 , wherein the one or more gram positive bacteria are Bacillus cereus, Staphylococcus aureus , or a combination thereof.

5. The method of treating the microbial infection of claim 3 , wherein the one or more gram negative bacteria are Pseudomonas aeruginosa, Escherichia coli , or a combination thereof.

6. The method of treating the microbial infection of claim 2 , wherein the one or more fungi are Aspergillus flavus, Chrysosporium keratinophilum , or a combination thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2024
From: AHMED, HANY MOHAMED ABD EL-LATEEF; ALI, MAI MOSTAFA KHALAF; AHMED, ANTAR AHMED ABDELHAMID; AMER, AMER A.
To: KING FAISAL UNIVERSITY
Reel/Frame 066574/0663 →
Continuity (1)
Division 18488969 · Oct 17, 2023