IP Library › Granted Patent US 12,180,245
Granted Patent B1
US 12,180,245 · App. 18/395,180 · Granted Dec 31, 2024

Separation and identification of myricetin-3-ogalactoside from casuarina glauca

Inventors: Maged Elsayed Mohamed (Al-Ahsa, SA); Nancy Safwat Younis (Al-Ahsa, SA); Bandar Essa Eldubiab (Al-Ahsa, SA); Azza M. El Shafae (Zagazig, EG); Nora Tawfeek (Zagazig, EG); Eman Fikry (Zagazig, EG)
Assignee: KING FAISAL UNIVERSITY
C07H1/08A61K36/185C07H17/07A61K2236/15A61K2236/333A61K2236/51
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Quick Facts
Patent No.
US 12,180,245
App. No.
18/395,180
Granted
Dec 31, 2024
Kind
B1
Abstract

The disclosure of the present patent application relates generally to the separation and identification of myricetin-3-O-galactoside from Casuarina glauca Sieber branchlets.

Claims (15)

1. A process for separation and identification of myricetin-3-O-galactoside comprising:

providing fresh branchlets of a Casuarina glauca plant;

shade drying and powdering the fresh branchlets to obtain a Casuarina glauca plant powder;

soaking 300 g of the Casuarina glauca plant powder with 70% ethyl alcohol to obtain a Casuarina glauca plant extract;

concentrating the Casuarina glauca plant extract to obtain a residue;

dissolving the residue to obtain an aqueous mixture;

mixing and sonicating the aqueous mixture;

centrifuging the aqueous mixture to obtain a supernatant;

separating myricetin-3-O-galactoside from the supernatant; and

wherein the soaking step is repeated three times in successive portions of 1 L of the 70% ethyl alcohol.

2. The process of claim 1 , wherein the plant is Casuarina glauca Sieber.

3. The process of claim 1 , wherein the supernatant is about 1 ml of a mobile phase solution comprising water:methanol:acetonitrile (50:25:25).

4. The process of claim 1 , wherein the mixing and sonicating step comprises:

vortexing the aqueous mixture for about 2 minutes; and

subjecting the aqueous mixture to ultrasonication for about 10 minutes.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2024
From: MOHAMED, MAGED ELSAYED; YOUNIS, NANCY SAFWAT; ELDUBIAB, BANDAR ESSA; EL SHAFAE, AZZA M.; TAWFEEK, NORA; FIKRY, EMAN
To: KING FAISAL UNIVERSITY
Reel/Frame 066121/0531 →