Catheter ultrasound ablation
Apparatus and methods are described including positioning an ultrasound transducer at a blood vessel ostium, rotating the transducer about its axis and scanning tissue of the blood vessel ostium, recording one or more baseline returned signals from the tissue, and creating a baseline image of the blood vessel ostium based on at least one of the returned signals. Tissue of the blood vessel ostium is ablated in consecutive segments by rotating the transducer segmentally until full rotation is completed. The returned signals of the ablated segments are recorded in real-time and a real-time image is created based on the one or more returned signals. Ablation is terminated after changes in the real-time returned signals and/or real-time image with respect to the baseline returned signals and/or baseline image indicate an achieved predetermined level of ablation lesion formation. Other applications are also described.
1. A method for ablating an ostium of a blood vessel of a subject that extends from a chamber of a heart of the subject, the method comprising:
positioning an ultrasound transducer at the blood vessel ostium that extends from the chamber of the heart;
rotating the transducer about its axis and scanning tissue of the blood vessel ostium;
recording one or more baseline returned signals from the tissue and creating a baseline image of the blood vessel ostium based on at least one of the returned signals;
ablating tissue of the blood vessel ostium in consecutive segments by rotating the transducer segmentally until full rotation is completed;
recording the returned signals of the ablated segments in real-time with respect to the ablation of the ablated segments, and creating a real-time image based on the one or more returned signals;
comparing the real-time returned signals or the real-time image to the baseline returned signals image;
identifying changes in the real-time returned signals or real-time image with respect to the baseline returned signals or baseline image that represent changes in the tissue that correspond to ablation lesion formation; and
terminating ablation after the identified changes indicate an achieved predetermined level of ablation lesion formation.
2. The method according to claim 1 , wherein the ultrasound transducer includes at least one scanning ultrasound piezoelectric element and at least one ablating ultrasound piezoelectric element, and wherein scanning the tissue comprises scanning the tissue using the at least one scanning ultrasound piezoelectric element, and ablating the tissue comprises ablating the tissue using the at least one ablating ultrasound piezoelectric element.
3. The method according to claim 1 , wherein the ultrasound transducer includes at least two ablating ultrasound piezoelectric elements, and wherein ablating the tissue comprises ablating the tissue using the at least two ablating ultrasound piezoelectric elements.
4. The method according to claim 1 , wherein ablating tissue of the blood vessel ostium comprises creating two circumferential ring-lesions.
5. The method according to claim 1 , wherein the blood vessel includes a pulmonary vein, and the chamber of the heart includes a left atrium and wherein the method is for use with the pulmonary vein that extends from the left atrium.
6. A method comprising:
advancing into an atrium of a heart of a subject:
a catheter ultrasound transducer including one or more piezoelectric elements of which at least one piezoelectric element is an ablative piezoelectric element and at least one piezoelectric elements is an imaging piezoelectric element, and
an expandable positioner positioned in contact with walls of a pulmonary vein ostium, and enveloping at least a portion of the catheter ultrasound transducer and being configured to allow the catheter ultrasound transducer to rotate and axially translate back and forth within the expandable positioner; and
activating the catheter ultrasound transducer to image tissue at the pulmonary vein ostium of the subject by using the imaging piezoelectric element.
7. The method according to claim 6 , further comprising activating the catheter ultrasound transducer to ablate tissue at the pulmonary vein ostium of the subject by using the ablative piezoelectric element.