IP Library › Granted Patent US 12,290,374
Granted Patent B2
US 12,290,374 · App. 17/625,636 · Granted May 6, 2025

System and method for testing the effects of ultraviolet and visible light on skin

Inventors: Indermeet Kohli (Westland, MI); Iltefat H. Hamzavi (Northville, MI); Henry W. Lim (Grosse Pointe, MI); Angela Miller (Belleville, MI); Tasneem Mohammad (Canton, MI); Cynthia Nicholson (Royal Oak, MI); Suteeraporn Chaowattanapanit (Nakhon Ratchasima, TH)
Assignee: Henry Ford Health System
A61B5/441A61N5/06F21S8/006F21V9/02A61B2503/42A61N2005/0661A61N2005/0662
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Quick Facts
Patent No.
US 12,290,374
App. No.
17/625,636
Granted
May 6, 2025
Kind
B2
Abstract

A system and method for testing an effect of light exposure on a skin sample include a solar simulator arranged to administer a combination of visible light (VL) and long wavelength ultraviolet radiation (UVA1) to the skin sample. The solar simulator includes a lamp for generating a light beam and at least one customized filter for receiving the light beam and emitting a VL+UVA1 spectral output having a wavelength range of 370-700 nm for irradiating the skin sample.

Claims (16)

1. A system for testing an effect of light exposure on a skin sample, the system comprising:

a solar simulator arranged to administer a combination of visible light (VL) and long wavelength ultraviolet radiation (UVA1) to the skin sample, the solar simulator including

a light source for generating a light beam; and

a filter combination including an interference filter for receiving the light beam and emitting a VL+UVA1 spectral output having a wavelength range of 370-700 nm with 2.0%-5% UVA1 (370-400 nm) for irradiating the skin sample.

2. The system of claim 1 , wherein the filter combination includes a long pass filter.

3. The system of claim 1 , wherein a total irradiance of the VL+UVA1 spectral output is between 40-500 mW/cm 2 .

4. The system of claim 1 , wherein the effect on the skin sample includes changes in at least one of pigmentation or erythema.

5. The system of claim 1 , wherein the light source includes a xenon arc lamp.

6. A method for testing an effect of light exposure on a skin sample, the method comprising:

providing a solar simulator arranged to administer a combination of visible light (VL) and long wavelength ultraviolet radiation (UVA1) to the skin sample, the solar simulator including a light source for generating a light beam and a filter combination including an interference filter for receiving the light beam and emitting a VL+UVA1 spectral output having a wavelength range of 370-700 nm with 2.0%-5% UVA1 (370-400 nm); and

irradiating the skin sample with the VL+UVA1 spectral output.

7. The method of claim 6 , wherein the filter combination includes a long pass filter.

8. The method of claim 6 , wherein a total irradiance of the VL+UVA1 spectral output is between 40-500 mW/cm 2 .

9. The method of claim 6 , wherein the effect on the skin sample includes changes in at least one of pigmentation or erythema.

10. The method of claim 6 , further comprising treating the skin sample with a photoprotective substance prior to irradiation.

11. The method of claim 6 , wherein the light source includes a xenon arc lamp.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 24, 2022
From: KOHLI, INDERMEET; HAMZAVI, ILTEFAT H.; LIM, HENRY W.; MILLER, ANGELA; MOHAMMAD, TASNEEM; NICHOLSON, CYNTHIA; CHAOWATTANAPANIT, SUTEERAPORN
To: HENRY FORD HEALTH SYSTEM
Reel/Frame 059384/0548 →
Continuity (2)
Provisional Application 62871897 · Jul 9, 2019
Related Publication 20220240838A1 · Aug 4, 2022
References Cited (14)
US 20030228267A1 · Aust et al. · 2003 [cited by applicant]
US 20090091325A1 · Haywood · 2009 [cited by applicant]
WO 0212127A2 · 2002 [cited by applicant]
WO 2018217432A1 · 2018 [cited by applicant]
Schalka et al. (Sunscreen protection against visible light: a new proposal for evaluation; 2012) Surg Cosmet Dermatol 2012;3(4):45-52. (Year: 2012). [cited by examiner]
Schalka et al. A novel method for evaluating sun visible light protection factor and pigmentation protection factor of sunscreens; Clinical, Cosmetic and Investigational Dermatology Aug. 2019:12 605-616 (Year: 2019). [cited by examiner]
European Extended Search Report for Application No. 20837322.5-1020, dated Jul. 31, 2023, 12 pages. [cited by applicant]
Kohli et al., “Synergistic effects of long-wavelength ultraviolet A1 and visible light on pigmentation and erytherma”, British Journal of Dermatology, 2018, 178, pp. 1173-1180. [cited by applicant]
Mahmoud et al., “Impact of Long Wavelength UVA and Visible Light on Melanocompetent Skin”, Journal of Investigative Dermatology, 2010, vol. 130, pp. 2092-2097. [cited by applicant]
De Argila D et al., “Study of Idiopathic, Exogenous Photodermatoses, Part II: Photobiologic Testing”, Actas Dermosifiliograficas (English Edition), Elsevier, Amsterdam, NL, vol. 105, No. 3, Feb. 27, 2014, pp. 233-242. [cited by applicant]
Schott, “Schott Optical Glass 2018”, Jan. 1, 2018, 147 pages. [cited by applicant]
International Search Report and Written Opinion for Application No. PCT/US2020/041389, dated Oct. 8, 2020, 9 pages. [cited by applicant]
International Preliminary Report on Patentability for Application No. PCT/US2020/041389, dated Jan. 11, 2022, 8 pages. [cited by applicant]
Kohli et al., “Synergistic effects of long-wavelength ultraviolet A1 and visible light on pigmentation and erytherma”, British Journal of Dermatology, 2018, 178, pp. 1173-1180, with Supplementary Materials and Methods S… [cited by applicant]