Systems and methods for automatic treatment planning and optimization
Systems and methods for the automatic generation and optimization of radiation therapy treatment plans, and systems and methods for the automatic generation and optimization of an adapted plan in an adaptive radiation therapy workflow.
1. An automatic treatment planning system, comprising:
a user interface; and
a treatment planning module configured to automatically generate a treatment plan based on objectives derived for clinical goals received via the user interface,
wherein the objectives include dose objectives and helper objectives.
2. The system of claim 1 , wherein the helper objectives are automatically generated.
3. The system of claim 2 , wherein a helper objective is generated for each of the clinical goals that are missing adequate dose information.
4. The system of claim 3 , wherein the treatment planning module comprises:
a quality metric generator generating quality metrics based on the clinical goals;
a dose objective generator configured to automatically generate a helper objective for each of the quality metrics, each helper objective shaping a dose objective of a respective quality metric;
a cost function generator configured to generate a cost function representing the objectives; and
an optimizer configured to generate the treatment plan based on the cost function.
5. The system of claim 4 , wherein the treatment planning module is further configured to evaluate the generated helper objectives for conflict with respective dose objectives.
6. The system of claim 5 , wherein the optimizer is configured to optimize the cost function and determine plan parameters for the treatment plan.
7. A method for automatically selecting helper objectives for a given input of clinical goals, comprising:
generating dose objectives for the clinical goals; and
when the dose objectives do not achieve a desired dose coverage, automatically generate helper objectives to shape the dose objectives of respective clinical goals,
wherein the generating of the helper objectives includes offsetting dose or volume positions of DVH curves generated for the clinical goals.
8. The method of claim 7 , wherein the input clinical goals are prioritized clinical goals.
9. A method for generating helper objectives for a given input of clinical goals, comprising:
determining whether the input clinical goals contain sufficient information to describe a desired dose coverage; and
automatically generating supplementary information to help achieve the desired dose coverage when it is determined that the input clinical goals do not contain sufficient information,
the supplementary information including objectives that help (helper objectives) provide for dose coverage missing from dose objectives derived for the input clinical goals.
10. The method of claim 9 , wherein the automatic generation of the helper objectives includes applying an algorithm to automatically offset dose and/or volume positions of dose-volume histogram (DVH) curves representing dose coverage fulfilling the dose objectives of the input clinical goals.
11. The method of claim 10 , wherein the offsetting of the dose and/or volume positions includes adding or placing additional dose objectives at different dose-volume positions of the dose-volume histogram (DVH) curves to include the missing dose coverage.
12. The method of claim 11 , wherein the helper objectives help shape the dose in a vicinity of a target structure by restricting dose values that are higher than a predetermined amount outside of the target structure.
13. The method of claim 12 , wherein the algorithm is further configured to implement one or more assumptions, including a margin by which the input clinical goals need to be met, and uniformity of dose to the target structure.
14. The method of claim 13 , wherein the helper objectives shape the dose in the vicinity of the target structure based on one or more parameters including one or more of dose prescription, type of the target structure, clinical viability of the desired dose coverage, post-processing disturbance, and dose scaling.
15. The method of claim 14 , wherein the helper objectives include main helper objectives, min/max helper objectives, and additional helper objectives, wherein the main helper objectives are added to the dose-volume axis histogram curves at tighter dose-volume positions for clinical goals having highest priorities, the min/max helper objectives are added at heuristically determined positions, and the additional helper objectives are added at positions that are between the positions of the main helper objectives and the min/max helper objectives.
16. The method of claim 15 , wherein the additional helping objectives are spaced equally in the volume axis of the dose-volume histogram (DVH) curves.
17. The method of claim 16 , wherein the positions of the helper objectives on the dose axis of the dose-volume histogram (DVH) curves can be further offset to account for dose scaling.
18. The method of claim 9 , further comprising generating helper objectives that control the dose values outside of the target structures.
19. The method of claim 9 , further comprising evaluating the helper objectives for conflict between the helper objectives and the dose objectives of the input clinical goals.
20. The method of claim 9 , further comprising generating a treatment plan for a target structure based on the dose objectives and the helper objectives derived for the input clinical goals.