IP Library › Granted Patent US 12,329,639
Granted Patent B2
US 12,329,639 · App. 18/150,929 · Granted Jun 17, 2025

Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods

Inventors: Kevin Mauch (Windsor, CA); Joshua Dwork (Santa Rosa, CA)
Assignee: Twelve, Inc.
A61F2/243A61F2/2436A61F2/844A61B2017/00243A61F2/2427
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Quick Facts
Patent No.
US 12,329,639
App. No.
18/150,929
Granted
Jun 17, 2025
Kind
B2
Abstract

Delivery systems with telescoping capsules for delivering prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, a delivery capsule having a first housing, a second housing slidably disposed within a portion of the first housing, and a prosthetic device constrained within the first and second housings. During deployment, the first housing is moved in a first direction over the second housing, thereby releasing a first portion of the prosthetic device. Subsequently, fluid the second housing is moved in the first direction to release a second portion of the prosthetic device.

Claims (28)

1. A method for delivering a prosthetic heart valve device to a native valve of a heart of a human patient, the method comprising:

positioning a delivery capsule at a distal portion of an elongated catheter body within the heart, the delivery capsule carrying the prosthetic heart valve device, wherein the delivery capsule comprises a first housing configured to contain at least a first portion of the prosthetic heart valve device and a second housing slidably associated with a portion of the first housing, wherein the second housing is configured to contain a second portion of the prosthetic heart valve device;

mechanically moving the first housing in a first direction with respect to the second housing to release the first portion of the prosthetic heart valve device from the delivery capsule; and

hydraulically moving the second housing in the first direction to release the second portion of the prosthetic heart valve device from the delivery capsule.

2. The method of claim 1 , wherein the first direction is a distal direction.

3. The method of claim 1 , wherein the first direction is a proximal direction.

4. The method of claim 1 , wherein moving the second housing in the first direction comprises moving the second housing and the first housing together in the first direction.

5. The method of claim 1 , wherein mechanically moving the first housing comprises retracting tethers coupled to the first housing.

6. The method of claim 5 , wherein the tethers extend distally from the first housing and then proximally back to a handle such that proximally retracting the tethers moves the first housing distally.

7. The method of claim 1 , wherein the first housing is disposed over and overlaps with the second housing such that moving the first housing in the first direction comprises sliding the first housing over a portion of the second housing.

8. The method of claim 1 , wherein the delivery capsule moves an overall longitudinal length of less than 50 mm to release the first portion and the second portion of the prosthetic heart valve device.

9. A method for delivering a prosthetic heart valve device to a native valve of a heart of a human patient, the method comprising:

positioning a delivery capsule at a distal portion of an elongated catheter body within the heart, the delivery capsule carrying the prosthetic heart valve device, wherein the delivery capsule comprises a first housing configured to contain at least a first portion of the prosthetic heart valve device and a second housing slidably associated with a portion of the first housing, wherein the second housing is configured to contain a second portion of the prosthetic heart valve device;

mechanically moving the first housing in a first direction with respect to the second housing to release the first portion of the prosthetic heart valve device from the delivery capsule, wherein mechanically moving the first housing in the first direction comprises proximally retracting a first tether coupled to the first housing, thereby causing the first housing to move in the first direction; and

moving the second housing in the first direction to release the second portion of the prosthetic heart valve device from the delivery capsule.

10. The method of claim 9 , wherein moving the second housing comprises hydraulically moving the second housing.

11. The method of claim 9 , further comprising moving the first housing in a second direction opposite the first direction to recapture the first portion of the prosthetic heart valve device within the delivery capsule.

12. The method of claim 11 , wherein moving the first housing in the second direction comprises mechanically moving the first housing in the second direction.

13. The method of claim 12 , wherein mechanically moving the first housing in the second direction comprises proximally retracting a second tether coupled to the first housing, thereby causing the first housing to move in the second direction.

14. The method of claim 13 ,

wherein the first tether extends distally from the first housing, over a distal end portion of the second housing, into the second housing and then proximally back to a handle such that proximal retraction of the first tether moves the first housing distally, and

wherein the second tether extends proximally from the first housing around an arched feature disposed on an outer surface of the second housing, over the distal end portion of the second housing, into the second housing, and proximally back to the handle such that proximally retracting the second tether moves the first housing proximally.

15. The method of claim 9 , wherein the delivery capsule moves an overall longitudinal length of less than 40 mm to release the first portion and the second portion of the prosthetic heart valve device.

16. A method for delivering a prosthetic heart valve device to a native valve of a heart of a human patient, the method comprising:

positioning a delivery capsule at a distal portion of an elongated catheter body within the heart, the delivery capsule carrying the prosthetic heart valve device, wherein the delivery capsule comprises a first housing configured to contain at least a first portion of the prosthetic heart valve device and a second housing slidably associated with a portion of the first housing, wherein the second housing is configured to contain a second portion of the prosthetic heart valve device;

moving the first housing in a first direction with respect to the second housing to release the first portion of the prosthetic heart valve device from the delivery capsule; and

moving the second housing in the first direction release the second portion of the prosthetic heart valve device from the delivery capsule,

wherein the first housing has a length of 20 mm to 30 mm, the second housing has a length of 20 mm to 30 mm, and the first housing and second housing overlap such that an overall length of the delivery capsule is 50 mm or less.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 6, 2023
From: MAUCH, KEVIN; DWORK, JOSHUA
To: TWELVE, INC.
Reel/Frame 062293/0709 →
Continuity (3)
Continuation 16870012 · May 8, 2020
Continuation 15611823 · Jun 2, 2017
Related Publication 20230144613A1 · May 11, 2023
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