IP Library › Granted Patent US 12,350,149
Granted Patent B2
US 12,350,149 · App. 17/066,443 · Granted Jul 8, 2025

Method and apparatus for repairing a heart valve

Inventors: Eran Miller (Moshav Beit Elazari, IL); Oz Cabiri (Hod Hasharon, IL); Yosef Gross (Moshav Mazor, IL); Amir Gross (Tel Aviv-Jaffa, IL); Tal Reich (Moledet, IL)
Assignee: Edwards Lifesciences Innovation (Israel) Ltd.
A61F2/2427A61B17/0401A61F2/2457A61F2/2466A61F2/2487A61B2017/00243A61B2017/0409A61B2017/0414A61B2017/0441A61B2017/0464A61B2017/0496A61B2017/0649A61B2017/12095
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Quick Facts
Patent No.
US 12,350,149
App. No.
17/066,443
Filed
Oct 8, 2020
Granted
Jul 8, 2025
Kind
B2
Art Unit
3771
USPC
623/2.11
Abstract

An implantable prosthetic device for repairing a native valve includes a first clip, a second clip, a first cord, and a second cord. The first clip has a first arm and a second arm and is moveable between an open position and a closed position. The second clip has a third arm and a fourth arm and is moveable between an open position and a closed position. The first cord is operatively coupled to the first clip for moving the first clip between the open and closed position. The second cord is operatively coupled to the second clip for moving the second clip between the open and closed position. The device is configured to clamp a first leaflet of the native mitral valve between the first arm and the second arm and to clamp a second leaflet of the native mitral valve between the third arm and the fourth arm.

Claims (44)

1. An implantable prosthetic device for repairing a native mitral valve of a heart, comprising:

a first clip having a first arm and a second arm pivotably coupled to the first arm, the first clip is moveable between an open position and a closed position;

a second clip having a third arm and a fourth arm pivotably coupled to the third arm, the second clip is moveable between an open position and a closed position;

a first cord operatively coupled to the first clip for moving the first clip between the open and closed position;

a second cord operatively coupled to the second clip for moving the second clip between the open and closed position;

wherein the first arm is configured to engage an atrial side of a first mitral valve leaflet and the second arm is configured to engage a ventricular side of the first mitral valve leaflet to clamp the first leaflet of the native mitral valve between the first arm and the second arm such that the first clip is connected to a portion of the first mitral valve leaflet;

wherein the third arm is configured to engage an atrial side of a second mitral valve leaflet and the fourth arm is configured to engage a ventricular side of the second mitral valve leaflet to clamp a second leaflet of the native mitral valve between the third arm and the fourth arm such that the second clip is connected to a portion of the second mitral valve leaflet; and

wherein, the first clip and the second clip are moveable with respect to one another such that while the portion of the first mitral valve leaflet is connected to the first clip and the portion of the second mitral valve leaflet is connected to the second clip, the portion of the first mitral valve leaflet that is connected to the first clip and the portion of the second mitral valve leaflet that is connected to the second clip move relative to another during the natural cardiac cycle.

2. The implantable prosthetic device of claim 1 , wherein the first clip includes at least one coupling protrusion on at least one of the first arm and the second arm.

3. The implantable prosthetic device of claim 2 , wherein the at least on coupling protrusion punctures the first leaflet.

4. The implantable prosthetic device of claim 1 , wherein the first clip is biased toward the closed position.

5. The implantable prosthetic device of claim 1 , wherein the first clip is configured to move from the closed position to the open position by pulling on the first cord.

6. The implantable prosthetic device of claim 5 , wherein the first clip is configured to move from the open position to the closed position by releasing or slackening the first cord.

7. The implantable prosthetic device of claim 1 , further comprising a spacer positioned between the first leaflet and the second leaflet, wherein the first clip and the second clip are supported by the spacer.

8. The implantable prosthetic device of claim 1 , wherein the first clip is spaced apart from an annulus of the native mitral valve when connected to the first leaflet.

9. The implantable prosthetic device of claim 1 , wherein the first clip is connected to a free end of the first mitral valve leaflet.

10. An implantable prosthetic device for repairing a native mitral valve of a heart, comprising:

a first clip having a first arm and a second arm pivotably coupled to the first arm, the first clip is moveable between an open position and a closed position;

a second clip having a third arm and a fourth arm pivotably coupled to the third arm, the second clip is moveable between an open position and a closed position;

a first cord operatively coupled to the first clip for moving the first clip between the open and closed position;

a second cord operatively coupled to the second clip for moving the second clip between the open and closed position;

wherein the device is configured to clamp a portion of a first leaflet of the native mitral valve between the first arm and the second arm such that the first clip is connected to the portion of the first leaflet;

wherein the device is configured to clamp a portion of a second leaflet of the native mitral valve between the third arm and the fourth arm such that the second clip is connected to the portion of the second leaflet;

wherein the device is configured such that when the first clip clamps the first leaflet, the first arm engages the first leaflet on an atrial side of the first leaflet and the second arm engages the first leaflet on a ventricular side of the first leaflet;

wherein the device is configured such that when the second clip clamps the second leaflet, the third arm engages the second leaflet on an atrial side of the second leaflet and the fourth arm engages the second leaflet on a ventricular side of the second leaflet;

wherein the device is configured to move the first clip and the second clip toward each other to move the first leaflet and the second leaflet together; and

wherein, the first clip and the second clip are movable with respect to one another such that when the portion of the first mitral valve leaflet is connected to the first clip and the portion of the second mitral valve leaflet is connected to the second clip, the portion of the first mitral valve leaflet that is connected to the first clip and the portion of the second mitral valve leaflet that is connected to the second clip move relative to one another during the natural cardiac cycle.

11. The implantable prosthetic device of claim 10 further comprising a spacer connected to the first clip and the second clip.

12. The implantable prosthetic device of claim 11 , wherein the first clip and the second clip are supported by the spacer.

13. The implantable prosthetic device of claim 10 , wherein the first clip includes at least one coupling protrusion on at least one of the first arm and the second arm.

14. The implantable prosthetic device of claim 13 , wherein the at least one coupling protrusion punctures the first leaflet.

15. The implantable prosthetic device of claim 10 , wherein the first clip is biased toward the closed position.

16. The implantable prosthetic device of claim 10 , wherein the first clip is configured to move from the closed position to the open position by pulling on the first cord.

17. The implantable prosthetic device of claim 16 , wherein the first clip is configured to move from the open position to the closed position by releasing or slackening the first cord.

18. The implantable prosthetic device of claim 10 , wherein the first clip is spaced apart from an annulus of the native mitral valve when connected to the first leaflet.

19. The implantable prosthetic device of claim 10 , wherein the first clip is connected to a free end of the first leaflet.

20. An implantable prosthetic device for repairing a native valve of a heart, comprising:

a first clip having a first arm and a second arm pivotably coupled to the first arm, the first clip is moveable between an open position and a closed position;

a second clip having a third arm and a fourth arm pivotably coupled to the third arm, the second clip is moveable between an open position and a closed position;

a first cord operatively coupled to the first clip for moving the first clip between the open and closed position;

a second cord operatively coupled to the second clip for moving the second clip between the open and closed position;

wherein the first arm is configured to engage an atrial side of a first native valve leaflet and the second arm is configured to engage a ventricular side of the first native valve leaflet to clamp the first leaflet of the native valve between the first arm and the second arm such that the first clip is connected to a portion of the first native valve leaflet;

wherein the third arm is configured to engage an atrial side of a second native valve leaflet and the fourth arm is configured to engage a ventricular side of the second native valve leaflet to clamp a second leaflet of the native valve between the third arm and the fourth arm such that the second clip is connected to a portion of the second native valve leaflet; and

wherein, the first clip and the second clip are moveable with respect to one another such that while the portion of the first native valve leaflet is connected to the first clip and the portion of the second native valve leaflet is connected to the second clip, the portion of the first native valve leaflet that is connected to the first clip and the portion of the second native valve leaflet that is connected to the second clip move relative to another during the natural cardiac cycle.

Assignments (2)
CHANGE OF NAME Recorded May 12, 2025
From: VALTECH CARDIO, LTD.
To: EDWARDS LIFESCIENCES INNOVATION (ISRAEL) LTD.
Reel/Frame 071276/0038 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2021
From: MILLER, ERAN; CABIRI, OZ; GROSS, YOSSI; GROSS, AMIR; REICH, TAL
To: VALTECH CARDIO, LTD.
Reel/Frame 056520/0277 →
Continuity (6)
Continuation 16714547 · Dec 13, 2019
Continuation 15042329 · Feb 12, 2016
Continuation 13319007
Continuation In Part 12548991 · Aug 27, 2009
Continuation In Part 12435291 · May 4, 2009
Related Publication 20210022858A1 · Jan 28, 2021
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