Granted Patent B2

US 12,377,622 · App. 16/837,972 · Granted Aug 5, 2025

Inventors: Robert Rosen (Groningen, NL); Franck Emmanuel Gounou (Groningen, NL); Carmen Canovas Vidal (Groningen, NL); Aixa Alarcon Heredia (Groningen, NL)

Assignee: AMO Groningen B.V.

B29D11/00461A61F2/1627A61F9/00834A61F2/16A61F2/482

Abstract

Claims (18)

1. A system for improving vision of a subject, the system comprising:

a pulsed laser system configured to modify a refractive index of at least one selected area of an intraocular lens (IOL) through refractive index writing, wherein the IOL is implanted in an eye of a subject, the pulsed laser system comprising a light source for generating and emitting a plurality of laser pulses, wherein the refractive index writing comprises applying the plurality of laser pulses emitted by the light source to the at least one selected area of the IOL, wherein the at least one selected area of the IOL defines an optical profile induced by the refractive index writing, the optical profile being an internal portion of the IOL that affects a transmission of light through the IOL;

a control system coupled to the pulsed laser system, the control system comprising a processor and memory, the memory having instructions stored thereon that, when executed by the processor, cause the control system to:

determine a direction of a plurality of rays associated with a vergence of a wavefront between a cornea of the eye of the subject and the IOL, wherein the plurality of rays are associated with incident light entering the eye of the subject;

determine a ray direction and a ray height of the plurality of rays at a first location of the optical profile corresponding to where the plurality of rays enter the optical profile of the IOL;

determine the refractive index of the optical profile at the first location; and

calculate a pattern in which to apply the plurality of laser pulses to the IOL by, in part, using vergence matching to specify a volume and a shape of each of a plurality of voxels in a corresponding voxel-based vergence-matched three-dimensional phase map such that the volume and shape of each of the plurality of voxels is configured to match the wavefront as the wavefront moves along a direction of propagation of the plurality of rays at the first location of the optical profile of the IOL, in that the shape and volume of each of the plurality of voxels decreases for converging wavefronts and increases for diverging wavefronts, wherein the specifying of the volume and the shape of each of the plurality of voxels is determined from the ray direction, the ray height, and the refractive index at the first location; and

operate the pulsed laser system to apply the plurality of laser pulses according to the calculated pattern.

2. The system of claim 1 , wherein anterior and posterior surfaces of the optical profile are curved such that the plurality of rays have zero incidence with respect to an interface between a surface of at least one other portion of the IOL and a respective surface of the optical profile.

3. The system of claim 2 , wherein the curve of the optical profile defines a non-zero curvature about an optical axis of the IOL.

4. The system of claim 1 , wherein the instructions further cause the control system to determine, for each ray of the plurality of rays, a second location of the optical profile where the ray exits the optical profile changed by refractive index writing.

5. The system of claim 4 , wherein the first location corresponds to a first plane parallel to a vertical axis of the IOL and the second location corresponds to a second plane parallel to the first plane.

6. The system of claim 4 , wherein the first location is proximate to or corresponds to an anterior surface of the IOL and wherein the second location is proximate to or corresponds to a posterior surface of the IOL.

7. The system of claim 1 , wherein the vergence matching further comprises creating a transformation function calculated by:

imaging an object at infinity through the cornea of the eye of the subject;

propagating the imaging of the object through the cornea to an anterior surface of the IOL based on a measured distance between the cornea of the eye of the subject and the anterior surface of the IOL, a shape of the anterior surface of the IOL, and a refractive index of the IOL;

imaging the object through the anterior surface of the IOL; and

propagating the imaging of the object through the anterior surface to the optical profile of the IOL.

Assignments (1)

Continuity (2)

References Cited (400)