Medicament delivery device and actuation mechanism for a drug delivery device
Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device.
1. An auto-injector comprising:
a housing;
a first sleeve comprising a first indicator of a first color, the first sleeve configured to move relative to the housing while remaining concentric to the housing; and
a second sleeve comprising a second indicator of a second color different than the first color, the first sleeve configured to move relative to the second sleeve while remaining concentric to the second sleeve, the first sleeve extending axially from the second sleeve, and a distal end of the second sleeve being larger than a distal end of the first sleeve,
wherein the auto-injector is configured such that when the auto-injector is pressed against an injection site, the distal end of the second sleeve touches the injection site, and a movement of the first sleeve relative to the housing is required before the auto-injector can insert a needle into the injection site and deliver a medicament,
wherein the first indicator and the second indicator are indicative of an injection process of the auto-injector, and the auto-injector is configured such that after the injection process, the auto-injector can be withdrawn from the injection site such that a compression spring relaxes to cause the needle to be covered by the auto-injector, and
wherein the housing comprises a latch member, and the first sleeve comprises a groove configured to receive the latch member to lock the first sleeve in a position relative to the housing in which a distal needle tip of the needle is covered by the auto-injector.
2. The auto-injector of claim 1 , wherein the auto-injector is configured to provide a tactile feedback in a form of a resistance for allowing a patient to distinguish two steps of the injection process.
3. The auto-injector of claim 1 , wherein a distal end of the auto-injector defines a distal opening and has an exterior tapered profile, the exterior tapered profile having a dimension that varies along a longitudinal axis of the auto-injector.
4. The auto-injector of claim 1 , comprising a syringe containing the medicament and comprising the needle, wherein the medicament comprises a glucagon-like peptide-1 (GLP-1) or an analogue or derivative thereof.
5. An auto-injector comprising:
a housing;
a first sleeve comprising a first indicator of a first color, the first sleeve configured to move relative to the housing while remaining concentric to the housing; and
a second sleeve comprising a second indicator of a second color different than the first color, the first sleeve configured to move relative to the second sleeve while remaining concentric to the second sleeve, the first sleeve extending axially from the second sleeve, and a distal end of the second sleeve being larger than a distal end of the first sleeve,
wherein the auto-injector is configured such that when the auto-injector is pressed against an injection site, the distal end of the second sleeve touches the injection site, and a movement of the first sleeve relative to the housing allows the auto-injector to insert a needle into the injection site and deliver a medicament,
wherein the first indicator and the second indicator are indicative of an injection process of the auto-injector, and
wherein the housing comprises a latch member, and the first sleeve comprises a groove configured to receive the latch member to lock the first sleeve in a position relative to the housing in which a distal needle tip of the needle is covered by the auto-injector.
6. The auto-injector of claim 5 , wherein a distal end of the auto-injector defines a distal opening and has an exterior tapered profile, the exterior tapered profile having a dimension that varies along a longitudinal axis of the auto-injector.
7. The auto-injector of claim 5 , wherein the first and second sleeves are axially movable relative to one another.
8. The auto-injector of claim 5 , wherein the first sleeve has a first axially-extending portion, the second sleeve has a second axially-extending portion, and the housing has a third-axially extending portion.
9. The auto-injector of claim 8 , wherein a distal end of the second axially-extending portion is larger than a distal end of the first axially-extending portion.
10. The auto-injector of claim 8 , wherein the auto-injector is configured to allow the first axially-extending portion of the first sleeve to be inside the second axially-extending portion of the second sleeve.
11. The auto-injector of claim 5 , wherein the auto-injector is configured such that after the injection process, the auto-injector can be withdrawn from the injection site such that a compression spring relaxes to cause the needle to be covered by the auto-injector.
12. The auto-injector of claim 5 , wherein the auto-injector is configured to provide a tactile feedback in a form of a resistance for allowing a patient to distinguish two steps of the injection process.
13. The auto-injector of claim 5 , comprising a syringe containing the medicament and comprising the needle, wherein the medicament comprises a glucagon-like peptide-1 (GLP-1) or an analogue or derivative thereof.
14. An auto-injector comprising:
a housing;
a first sleeve comprising a first indicator of a first color, the first sleeve configured to move relative to the housing while remaining concentric to the housing; and
a second sleeve comprising a second indicator of a second color different than the first color, the first sleeve configured to move relative to the second sleeve while remaining concentric to the second sleeve, the first sleeve extending axially from the second sleeve, and a distal end of the second sleeve being larger than a distal end of the first sleeve,
wherein the auto-injector is configured such that when the auto-injector is pressed against an injection site, the distal end of the second sleeve touches the injection site, and the auto-injector can insert a needle into the injection site and deliver a medicament,
wherein the first indicator and the second indicator are indicative of an injection process of the auto-injector, and
wherein the housing comprises a latch member, and the first sleeve comprises a groove configured to receive the latch member to lock the first sleeve in a position relative to the housing in which a distal needle tip of the needle is covered by the auto-injector.
15. The auto-injector of claim 14 , wherein a distal portion of the auto-injector has an exterior tapered profile with a dimension that varies along a longitudinal axis of the auto-injector.
16. The auto-injector of claim 15 , wherein a proximal portion of the auto-injector that extends distally from the distal portion of the auto-injector is substantially cylindrical.
17. The auto-injector of claim 14 , wherein the first and second sleeves are axially movable relative to one another.
18. The auto-injector of claim 14 , wherein the first sleeve has a first axially-extending portion, the second sleeve has a second axially-extending portion, and the housing has a third-axially extending portion, and a distal end of the second axially-extending portion is larger than a distal end of the first axially-extending portion.
19. The auto-injector of claim 18 , wherein the auto-injector is configured to allow the first axially-extending portion of the first sleeve to be inside the second axially-extending portion of the second sleeve.
20. The auto-injector of claim 14 , wherein the auto-injector is configured such that after the injection process, the auto-injector can be withdrawn from the injection site such that a compression spring relaxes to cause the needle to be covered by the auto-injector.
21. The auto-injector of claim 20 , wherein the auto-injector is configured to provide a tactile feedback for allowing a patient to distinguish two steps of the injection process.
22. The auto-injector of claim 14 , comprising a syringe containing the medicament and comprising the needle, wherein the medicament comprises a glucagon-like peptide-1 (GLP-1) or an analogue or derivative thereof.