IP Library › Granted Patent US 12,427,249
Granted Patent B2
US 12,427,249 · App. 17/270,616 · Granted Sep 30, 2025

Fluid injector system with improved ratio performance

Inventors: Amy Chaya (Strafford, PA); Michael Spohn (Fenelton, PA); Michael McDermott (Pittsburgh, PA); William Barone (Pittsburgh, PA)
Assignee: BAYER HEALTHCARE LLC
A61M5/16827A61M5/1408A61M5/1422A61M2005/14208A61M2205/52
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Quick Facts
Patent No.
US 12,427,249
App. No.
17/270,616
Granted
Sep 30, 2025
Kind
B2
Abstract

A fluid injector system includes a control device operatively associated with a first drive component configured to pressurize and inject a first fluid and a second drive component configured to pressurize and inject a second fluid. The control device includes at least one processor programmed or configured to: during a first phase of a multi-phase injection protocol, actuate at least the first drive component to inject the first fluid; during the first phase of the multi-phase injection protocol and prior to transitioning to a second phase of the multi-phase injection protocol, actuate the second drive component to pressurize the second fluid relative to a pressure of the first fluid; and during the second phase of the multi-phase injection protocol, actuate the second drive component to inject at least the second fluid so that a desired steady-state ratio of the first fluid and the second fluid in the second phase is reached.

Claims (23)

1. A fluid injector system configured to perform an injection protocol comprising at least a first phase and a second phase, the second phase subsequent to the first phase, the fluid injector system comprising:

a control device operatively associated with a first drive component and a second drive component, the first drive component configured to pressurize and inject a first fluid from a first fluid reservoir through a fluid conduit, the second drive component configured to pressurize and inject a second fluid from a second fluid reservoir through the fluid conduit, and at least a first valve configured to control fluid communication between the first fluid reservoir and the fluid conduit and a second valve configured to control fluid communication between the second fluid reservoir and the fluid conduit, the first valve and the second valve controlled by at least one processor of the control device between an open position and a closed position,

wherein the at least one processor is programmed or configured to:

during the first phase of the injection protocol, actuate at least the first drive component to inject the first fluid through the fluid conduit and operate the second valve to the closed position;

during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol, actuate the second drive component and maintain the second valve in the closed position to pressurize the second fluid relative to a pressure of the first fluid in the fluid conduit, wherein pressurizing of the second fluid relative to the pressure of the first fluid comprises selecting a pressure ratio of the pressure of the first fluid and a pressure of the second fluid to reach a desired steady-state flow ratio of the first fluid and the second fluid for the second phase of the injection protocol; and

during the second phase of the injection protocol, operate the second valve to the open position and actuate the second drive component to inject at least the second fluid through the fluid conduit so that the desired steady-state ratio of the first fluid and the second fluid in the second phase of the injection protocol is reached.

2. The fluid injector system of claim 1 , wherein the desired steady-state ratio of the first fluid and the second fluid in the second phase of the injection protocol is reached at a quicker rate than if the second drive component is not actuated prior to the transitioning to the second phase of the injection protocol.

3. The fluid injector system of claim 1 , wherein the at least one processor is further programmed or configured to: during the first phase of the injection protocol prior to the transitioning to the second phase of the injection protocol, cease actuation or reduce a speed of the first drive component.

4. The fluid injector system of claim 1 , wherein the at least one processor is further programmed or configured to: during the second phase of the injection protocol, adjust a speed of the first drive component to inject the first fluid at a flow rate to reach the desired steady-state ratio of the first fluid and the second fluid through the fluid conduit.

5. The fluid injector system of claim 1 , wherein the pressurizing of the second fluid relative to the pressure of the first fluid comprises gradually increasing the pressure of the second fluid such that during the transitioning to the second phase of the injection protocol from the first phase of the injection protocol, the pressure of the second fluid is substantially equal to the pressure of the first fluid.

6. The fluid injector system of claim 1 , wherein the at least one processor is further programmed or configured to; during the first phase of the injection protocol prior to the transitioning to the second phase of the injection protocol, adjust at least one property of the injection protocol to prevent backflow of the first fluid into the second fluid reservoir.

7. The fluid injector system of claim 6 , wherein the adjusting of at least one property of the injection protocol comprises at least one of: advancing the second drive component at a constant speed, linearly increasing a speed of the second drive component, and exponentially increasing the speed of the second drive component.

8. A method of performing an injection protocol comprising at least a first phase and a second phase using a fluid injector system, the second phase subsequent to the first phase, the method comprising:

providing a control device of the fluid injector system operatively associated with a first drive component and a second drive component of the fluid injector system, the first drive component configured to pressurize and inject a first fluid from a first fluid reservoir through a fluid conduit, the second drive component configured to pressurize and inject a second fluid from a second fluid reservoir through the fluid conduit, and at least a first valve of the fluid injector system configured to control fluid communication between the first fluid reservoir and the fluid conduit and a second valve of the fluid injector system configured to control fluid communication between the second fluid reservoir and the fluid conduit, the first valve and the second valve controlled by at least one processor of the control device between an open position and a closed position;

actuating at least the first drive component to inject the first fluid through the fluid conduit and operating the second valve to the closed position during the first phase of the injection protocol;

actuating the second drive component and maintaining the second valve in the closed position to pressurize the second fluid relative to a pressure of the first fluid in the fluid conduit during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol, wherein pressurizing of the second fluid relative to the pressure of the first fluid comprises selecting a pressure ratio of the pressure of the first fluid and a pressure of the second fluid to reach a desired steady-state flow ratio of the first fluid and the second fluid for the second phase of the injection protocol; and

operating the second valve to the open position and actuating the second drive component to inject at least the second fluid through the fluid conduit so that the desired steady-state ratio of the first fluid and the second fluid in the second phase is reached during the second phase of the injection protocol.

9. The method of claim 8 , wherein the desired steady-state ratio of the first fluid and the second fluid in the second phase of the injection protocol is reached at a quicker rate than if the second drive component is not actuated prior to the transitioning to the second phase of the injection protocol.

10. The method of claim 8 , further comprising ceasing actuation or reducing a speed of the first drive component during the first phase of the injection protocol prior to the transitioning to the second phase of the injection protocol.

11. The method of claim 8 , further comprising adjusting a speed of the first drive component to inject the first fluid at a flow rate to reach the desired steady-state ratio of the first fluid and the second fluid through the fluid conduit during the second phase of the injection protocol.

12. The method of claim 8 , wherein pressurizing the second fluid relative to the pressure of the first fluid comprises gradually increasing the pressure of the second fluid such that, during the transitioning to the second phase of the injection protocol from the first phase of the injection protocol, the pressure of the second fluid is substantially equal to the pressure of the first fluid.

13. The method of claim 8 , further comprising adjusting at least one property of the injection protocol to prevent backflow of the first fluid into the second fluid reservoir during the first phase of the injection protocol prior to the transitioning to the second phase of the injection protocol.

14. The method of claim 13 , wherein the adjusting of at least one property of the injection protocol comprises at least one of: advancing the second drive component at a constant speed, linearly increasing a speed of the second drive component, and exponentially increasing the speed of the second drive component.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2021
From: CHAYA, AMY; SPOHN, MICHAEL; MCDERMOTT, MICHAEL; BARONE, WILLIAM
To: BAYER HEALTHCARE LLC
Reel/Frame 055371/0982 →
Continuity (2)
Provisional Application 62723724 · Aug 28, 2018
Related Publication 20210220557A1 · Jul 22, 2021
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