IP Library Granted Patent US 12,453,471
Granted Patent B2
US 12,453,471 · App. 18/306,407 · Granted Oct 28, 2025

Continuous detection and monitoring of heart arrhythmia using both wearable sensors and cloud-resident analyses

Inventors: Mark Murphy (Mountain View, CA); Nikhil Bikhchandani (San Francisco, CA)
Assignee: Verily Life Sciences LLC
A61B5/0022A61B5/0006A61B5/0205A61B5/02416A61B5/332A61B5/363A61B5/681A61B5/7221A61B5/7257A61B5/7264A61B5/7282A61B5/1118A61B2560/0242A61B2562/0219
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Quick Facts
Patent No.
US 12,453,471
App. No.
18/306,407
Granted
Oct 28, 2025
Kind
B2
Abstract

Systems and methods are provided for continuously monitoring a user to determine when cardiovascular events are likely occurring and to responsively provide a prompt to a user to engage in additional physiological assessment of the putative cardiovascular event. Additional assessment can include the user engaging an additional sensor to provide signals that are more accurate, lower noise, or otherwise improved relative to a continuously-monitoring sensor used to initially detect the cardiovascular event. Detection of cardiovascular events includes using a cardiovascular classifier to determine, based on the output of such a continuously-monitoring sensor, whether the event is likely occurring. Such a classifier can be received from a cloud computing service or other remote system based on sensor outputs sent to such a system. Use of such a classifier can facilitate reduced false-positive detection of cardiovascular events based on the continuously-monitoring sensor, and thus reduce extraneous prompts to the user.

Claims (34)

1. A server, wherein the server is configured to:

receive information indicative of a photoplethysmographic signal detected by a first sensor of a wearable device, wherein the wearable device is associated with a user;

determine information related to a cardiovascular classifier based on the information indicative of the photoplethysmographic signal detected by the first sensor at the wearable device, wherein the cardiovascular classifier is configured to predict whether a cardiovascular event is occurring based on an electrocardiographic signal detected by a second sensor of the wearable device, wherein the cardiovascular classifier is derived from photoplethysmographic data but is adapted to predict an occurrence of the cardio vascular event based on electrocardiographic data; and

transmit the information related to the cardiovascular classifier to the wearable device so that the cardiovascular classifier is stored at and used by the wearable device to detect the occurrence of the cardiovascular event with the second sensor that is a different type of sensor than the first sensor from which the cardiovascular classifier was derived.

2. The server of claim 1 , further comprising:

receive sensor data indicative of multiple sensor signals detected at-the wearable device, wherein the multiple sensor signals include at least the photoplethysmographic signal detected by the first sensor of the wearable device and the electrocardiographic signal detected by the second sensor of the wearable device;

determine information about one or more cardiovascular events of the user based on the sensor data indicative of the multiple sensor signals detected at the wearable device,

wherein the information about one or more cardiovascular events of the user comprises an existence of the one or more cardiovascular events of the user.

3. The server of claim 2 , wherein the information about one or more cardiovascular events of the user comprises a timing of the one or more cardiovascular events of the user.

4. The server of claim 2 , wherein the information about one or more cardiovascular events of the user comprises one or more properties of the one or more cardiovascular events of the user.

5. The server of claim 2 , wherein the server is further configured to:

determine one or more predictive features of one or more of the multiple sensor signals in relation to the one or more cardiovascular events of the user.

6. The server of claim 2 , wherein the server is further configured to:

make one or more determinations regarding a drug or treatment received by the user based on the information about the one or more cardiovascular events of the user.

7. The server of claim 6 , wherein the one or more determinations include an indication of an effectiveness of the drug or treatment received by the user.

8. The server of claim 1 , wherein the information related to the cardiovascular classifier comprises one or more of (i) pattern-matching templates, (ii) filter cutoffs, or (iii) parameters of a predictive algorithm.

9. The server of claim 1 wherein the server is configured to:

determine the information related to the cardiovascular classifier based further on information indicative of photoplethysmographic signals and electrocardiographic signals detected at a plurality of wearable devices.

10. A system comprising:

a wearable device associated with a user, wherein the wearable device comprises a first sensor configured to detect photoplethysmographic signals, a second sensor configured to detect electrocardiographic signals, and a controller; and

a server remote from the wearable device, wherein the server is configured to:

receive information indicative of photoplethysmographic signals detected by the first sensor at the wearable device;

determine information related to a cardiovascular classifier based on the information indicative of the photoplethysmographic signals detected by the first sensor at the wearable device, wherein the cardiovascular classifier is configured to predict whether a cardiovascular event is occurring based on the electrocardiographic signals detected by the second sensor of the wearable device, wherein the cardiovascular classifier is derived from photoplethysmographic data but is adapted to predict an occurrence of the cardio vascular event based on electrocardiographic data; and

transmit the information related to the cardiovascular classifier to the wearable device so that the cardiovascular classifier is stored in and executed by the controller of the wearable device to predict whether the cardiovascular event is occurring using the second sensor, which is a different type of sensor than the first sensor from which the cardiovascular classifier was derived.

11. The system of claim 10 , wherein the wearable device further comprises a communication interface for communicating with the server over one or more communication networks.

12. The system of claim 11 , wherein the communication interface comprises a wireless transceiver.

13. The system of claim 10 , wherein the server is further configured to:

receive sensor data indicative of multiple sensor signals detected at-the wearable device, wherein the multiple sensor signals include additional photoplethysmographic signals detected by the first sensor and additional electrocardiographic signals detected by the second sensor;

determine information about one or more cardiovascular events of the user based on the sensor data indicative of the multiple sensor signals detected at the wearable device, wherein the information about one or more cardiovascular events of the user comprises an existence of the one or more cardiovascular events of the user.

14. The system of claim 13 , wherein the information about one or more cardiovascular events of the user comprises a timing of the one or more cardiovascular events of the user.

15. The system of claim 13 , wherein the information about one or more cardiovascular events of the user comprises one or more properties of the one or more cardiovascular events of the user.

16. The system of claim 13 , wherein the server is further configured to:

make one or more determinations regarding a drug or treatment received by the user based on the information about the one or more cardiovascular events of the user.

17. The system of claim 16 , wherein the one or more determinations include an indication of an effectiveness of the drug or treatment received by the user.

Assignments (1)
CHANGE OF NAME Recorded Apr 1, 2026
From: VERILY LIFE SCIENCES LLC
To: VERILY HEALTH INC.
Reel/Frame 075367/0775 →
Continuity (4)
Continuation 17162247 · Jan 29, 2021
Continuation 16184754 · Nov 8, 2018
Provisional Application 62592203 · Nov 29, 2017
Related Publication 20230255489A1 · Aug 17, 2023
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