IP Library › Granted Patent US 12,458,413
Granted Patent B2
US 12,458,413 · App. 18/716,090 · Granted Nov 4, 2025

Fusion cages and methods for sacro-iliac joint stabilization

Inventors: Ali H. Mesiwala (Claremont, CA); Francois Follini (Austin, TX); Bret W. Schneider (San Jose, CA); Scott A. Yerby (Montara, CA)
Assignee: SI-Bone Inc.
A61B17/7055A61F2/4455A61F2002/30995
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Quick Facts
Patent No.
US 12,458,413
App. No.
18/716,090
Granted
Nov 4, 2025
Kind
B2
Abstract

Systems, devices and methods for vertebral fusion and SI joint stabilization.

Claims (63)

1 . A method of fusing vertebrae and stabilizing sacro-iliac joints of a subject, comprising:

implanting at least a portion of a fusion cage between an S1 vertebra and an L5 vertebra;

implanting a first SI joint stabilizing member such that,

a cage end region of the first SI joint stabilizing member interfaces with a first lateral portion of the fusion cage,

the first SI joint stabilizing member extends through an S1 endplate,

an ilium end of the first SI joint stabilizing member is implanted in a first ilium and is posterior, lateral and caudal relative to the fusion cage, and

an intermediate region of the first SI joint stabilizing member that is between the ilium end and the cage end region is implanted across a first SI joint; and

implanting a second SI joint stabilizing member such that,

a cage end region of the second SI joint stabilizing member interfaces with a second lateral portion of the fusion cage,

the second SI joint stabilizing member extends through the S1 endplate,

an ilium end of the second SI joint stabilizing member is implanted in a second ilium and is posterior, lateral and caudal relative to the fusion cage, and

an intermediate region of the second SI joint stabilizing member that is between the ilium end and the cage end region of the second SI joint stabilizing member is implanted across a second SI joint.

2 . The method of claim 1 , further comprising implanting an L5 stabilizing member such that a cage end region of the L5 stabilizing member interfaces with the fusion cage and an L5 end of the L5 stabilizing member is in the L5 vertebra and cephalad to the fusion cage.

3 . The method of claim 2 , wherein the cage region of the L5 stabilizing member is laterally between the first and second stabilizing members.

4 . The method of claim 1 , wherein implanting at least a portion of the fusion cage is initiated prior in time to implanting the first SI joint stabilizing member and implanting the second SI joint stabilizing member.

5 . The method of claim 1 , wherein implanting the first SI joint stabilizing member comprises implanting the first SI joint stabilizing member in a lateral, caudal and posterior trajectory relative to the fusion cage.

6 . The method of claim 5 , wherein implanting the second SI joint stabilizing member comprises implanting the second SI joint stabilizing member in a lateral, caudal and posterior trajectory relative to the fusion cage.

7 . The method of claim 1 , wherein implanting the first and second SI joint stabilizing members comprises rotationally implanting the first and second SI joint stabilizing members.

8 . The method of claim 1 , wherein implanting the first SI joint stabilizing member comprises advancing the first SI joint stabilizing member from the first ilium and across the first SI joint towards the fusion cage.

9 . The method of claim 1 , wherein implanting the second SI joint stabilizing member comprises implanting the second SI joint stabilizing member from the second ilium and across the second SI joint towards the fusion cage.

10 . The method of claim 1 , wherein implanting the first SI joint stabilizing member comprises coupling first and second members of the first SI joint stabilizing member in-situ.

11 . The method of claim 10 , wherein the first member is delivered through the first sacrum and towards the first ilium, and the second member is delivered from the first ilium and towards the first sacrum.

12 . The method of claim 10 , wherein implanting the second SI joint stabilizing member comprises coupling first and second members of the second SI joint stabilizing member in-situ.

13 . The method of claim 12 wherein the first member is delivered through the second sacrum towards the second ilium, and the second member is delivered from the second ilium and towards the second sacrum.

14 . The method of claim 1 , further comprising moving a first covering member of the fusion cage from an uncovered position to a covered position in which the first covering member covers at least a portion of the cage end region of the first SI joint stabilizing member.

15 . The method of claim 14 , further comprising moving a second covering member of the fusion cage from an uncovered position to a covered position in which the second covering member covers at least a portion of the cage end region of the second SI joint stabilizing member.

16 . The method of claim 14 , wherein moving the first covering member of the fusion cage from an uncovered position to a covered position also covers at least a portion of a cage end region of an L5 stabilizing member.

17 . A system for fusing vertebrae and stabilizing sacro-iliac joints of a subject, comprising:

a fusion cage sized and configured to be at least partially implanted between an S1 vertebra and an L5 vertebra;

a first SI joint stabilizing member; and

a second SI joint stabilizing member, wherein

the fusion cage comprising,

a first SI joint stabilizing member interface in an anterior portion and in a first lateral portion of the fusion cage,

the first SI joint stabilizing member interface having at least one surface sized and configured to stably interface with a cage end region of the first SI joint stabilizing member when the first SI joint stabilizing member extends posterior, caudal and lateral relative to the fusion cage such that an ilium end of the first SI joint stabilizing member is implanted in a first ilium of the patient, and

a second SI joint stabilizing member interface in an anterior portion and a second lateral portion of the fusion cage,

the second SI joint stabilizing member interface having at least one surface sized and configured to stably interface with a cage end region of the second SI joint stabilizing member when the second SI joint stabilizing member extends posterior, caudal and lateral relative to the fusion cage such that an ilium end of the second SI joint stabilizing member is implanted in a second ilium of the patient.

18 . The system of claim 17 , wherein the fusion cage further comprises an L5 stabilizing member interface in the anterior portion of the fusion cage and disposed laterally between the first and SI joint stabilizing member interfaces, the L5 stabilizing member interface sized and configured to stably interface with a cage end region of the L5 stabilizing member when an L5 end of the L5 stabilizing member is in the L5 vertebra and cephalad to the fusion cage.

19 . The system of claim 18 , wherein the L5 stabilizing member is shorter than the first and second SI joint stabilizing members.

20 . The system of claim 19 , wherein the L5 stabilizing member has a minor diameter that is less than minor diameters of the first and second SI joint stabilizing members.

21 . The system of claim 19 , wherein the first and second SI joint stabilizing members each have lengths from 60 mm to 100 mm.

22 . The system of claim 17 , wherein the first SI joint stabilizing member interface comprises a first channel that is oriented posterior, caudal and lateral relative to a midline of the fusion cage, and wherein the second SI joint stabilizing member interface comprises a second channel that is oriented posterior, caudal and lateral relative to the midline, the midline measured across a width of the fusion cage.

23 . The system of claim 22 , wherein the first channel is open on an anterior side of the first channel and is closed on a posterior side of the first channel, and wherein the second channel is open on an anterior side of the second channel and is closed on a posterior side of the second channel.

24 . The system of claim 17 , wherein the first SI joint stabilizing member interface comprises a channel configuration that is oriented laterally away from a midline of the fusion cage, the midline measured across a width of the fusion cage, and wherein the second SI joint stabilizing member interface comprises a second channel configuration that is oriented laterally away from the midline of the fusion cage.

25 . The system of claim 17 , wherein the first SI joint stabilizing member interface comprises a curved surface that is configured to engage with a curved surface of the cage end region of the first SI joint stabilizing member, and wherein the second SI joint stabilizing member interface comprises a curved surface that is configured to engage with a curved surface of the cage end region of the second SI joint stabilizing member.

26 . The system of claim 17 , wherein the first and second SI joint stabilizing members each have an intermediate single lead thread region that is axially in between dual lead thread regions.

27 . The system of claim 17 , wherein the first and second SI joint stabilizing members each have a length from 60 mm to 100 mm.

28 . The system of claim 17 , wherein the fusion cage further comprises a first covering member moveable from an uncovered position to a covered position in which the first covering member covers at least a portion of the cage end region of the first SI joint stabilizing member.

29 . The system of claim 28 , wherein the fusion cage further comprises a second covering member moveable from an uncovered position to a covered position in which the second covering member covers at least a portion of the cage end region of the second SI joint stabilizing member.

30 . The system of claim 28 , wherein in the covered position the first covering member of the fusion cage also covers at least a portion of a cage end region of an L5 stabilizing member.

31 . A fusion cage that is adapted for SI joint stabilization, comprising:

a body sized and configured to be at least partially implanted between an S1 vertebra and an L5 vertebra, the body including,

a first SI joint stabilizing member interface in an anterior portion and in a first lateral portion of the fusion cage, and

the first SI joint stabilizing member interface having at least one surface sized and configured to stably interface with a cage end region of a first SI joint stabilizing member when the first SI joint stabilizing member extends posterior, caudal and lateral relative to the body such that an ilium end of the first SI joint stabilizing member is implanted in a first ilium of the patient,

a second SI joint stabilizing member interface in the anterior portion and in a second lateral portion of the fusion cage, and

the second SI joint stabilizing member interface having at least one surface sized and configured to stably interface with a cage end region of a second SI joint stabilizing member when the second SI joint stabilizing member extends posterior, caudal and lateral relative to the body such that an ilium end of the second SI joint stabilizing member is implanted in a second ilium of the patient.

32 . The fusion cage of claim 31 , further comprising an L5 stabilizing member interface in the anterior portion of the fusion cage and disposed laterally between the first and SI joint stabilizing member interfaces, the L5 stabilizing member interface sized and configured to stably interface with a cage end region of an L5 stabilizing member when an L5 end of the L5 stabilizing member is in an L5 vertebra and cephalad to the body.

33 . The fusion cage of claim 32 , wherein the L5 stabilizing member interface has a smaller inner dimension than the first and second SI joint stabilizing member interfaces.

34 . The fusion cage of claim 32 , wherein the L5 stabilizing member interface has an axis that is aligned with a midline of the body, the midline measured across a width of the body.

35 . The fusion cage of claim 31 , wherein the first and second SI joint stabilizing member interfaces are the only stabilizing member interfaces that have an axis lateral to a midline of the body and that are in the anterior portion of the body.

36 . The fusion cage of claim 31 , wherein the first and second SI joint stabilizing member interfaces are each oriented such that when SI joint stabilizing members each having a length from 60 mm to 100 mm are interfaced with the stabilizing member interfaces, the SI joint stabilizing members extend further laterally than the body.

37 . The fusion cage of claim 31 , wherein the fusion cage further comprises a first covering member moveable from an uncovered position to a covered position in which the first covering member covers at least a portion of the first SI joint stabilizing member interface.

38 . The fusion cage of claim 37 , wherein the fusion cage further comprises a second covering member moveable from an uncovered position to a covered position in which the second covering member covers at least a portion of the second SI joint stabilizing member interface.

39 . The fusion cage of claim 37 , wherein in the covered position the first covering member of the fusion cage also covers at least a portion of a cage end region of an L5 stabilizing member.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2024
From: FOLLINI, FRANCOIS; SCHNEIDER, BRET W.; YERBY, SCOTT A.
To: SI-BONE INC.
Reel/Frame 068075/0863 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2024
From: MESIWALA, ALI H.
To: SI-BONE INC.
Reel/Frame 068075/0908 →
Continuity (2)
Provisional Application 63264921 · Dec 3, 2021
Related Publication 20250025216A1 · Jan 23, 2025
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