Granted Patent B2

US 12,465,770 · App. 17/360,643 · Granted Nov 11, 2025

Inventor: Vinod Sharma (Maple Grove, MN)

Assignee: Medtronic, Inc.

A61N1/3706A61N1/0565A61N1/0573A61N2001/058A61N2001/0585A61N1/3756

Abstract

Claims (31)

1 . An implantable medical system comprising:

an implantable catheter advanceable into a coronary sinus of a patient's heart, the catheter comprising a sheath body extending between a proximal portion and a distal portion, the catheter comprising a side lumen and an angled opening proximal to the distal portion in fluid communication with the side lumen, wherein the side lumen and the angled opening define a deflection angle configured to deflect a guide element and an implantable lead advanced therethrough proximate to a region of the cardiac conduction system in the myocardium of the patient's heart;

the guide element receivable in the side lumen, the guide element extending from a proximal portion to a distal portion, wherein the distal portion includes at least one testing electrode, wherein the guide element is advanceable through the angled opening to be deflected laterally away from the catheter at the deflection angle to position the at least one testing electrode proximate the region of the cardiac conduction system in a myocardium of the patient's heart when the distal portion of the catheter is positioned in the coronary sinus; and

the implantable lead receivable in the side lumen, the lead comprising a lead body extending from a proximal portion to a distal portion, wherein the implantable lead comprises an anchoring element disposed along the lead body and at least one pacing electrode disposed along the distal portion, wherein the at least one pacing electrode is configured to pace the region of the cardiac conduction system of the patient's heart, wherein the lead is advanceable through the angled opening to be deflected laterally away from the catheter at the deflection angle to implant the at least one pacing electrode proximate the region of the cardiac conduction system in the myocardium of the patient's heart to pace the cardiac conduction system of the patient's heart.

2 . The system according to claim 1 , wherein the anchoring element is positioned proximal to the at least one pacing electrode.

3 . The system according to claim 1 , wherein the anchoring element is integrally formed with the at least one pacing electrode.

4 . The system according to claim 1 , wherein the anchoring element comprises a helical structure configured to engage the coronary sinus vessel wall of the patient.

5 . The system according to claim 1 , wherein the lead is a bipolar lead and the at least one pacing electrode comprises two or more pacing electrodes.

6 . The system according to claim 1 , wherein the sheath body comprises a tapered tip portion distal to the angled opening.

7 . The system according to claim 6 , wherein the sheath body comprises an ultrasound visible tip portion extending distal to the tapered tip portion.

8 . The system according to claim 6 , wherein the side lumen is closed at the tapered tip portion.

9 . The system according to claim 1 , wherein the guide element and the lead are separately advanceable or retractable relative to one another.

10 . The system according to claim 1 , wherein the guide element is advanceable through a lead lumen of the lead to a potential implant location.

11 . A delivery system for an implantable medical device, the system comprising:

an implantable catheter advanceable into a coronary sinus of a patient's heart, the catheter comprising a sheath body extending between a proximal portion and a distal portion, the catheter comprising a side lumen and an angled opening proximal to the distal portion in fluid communication with the side lumen, wherein the side lumen and the angled opening define a deflection angle configured to deflect a guide element and an implantable lead advanced therethrough proximate to a region of the cardiac conduction system in the myocardium of the patient's heart;

the guide element receivable in the side lumen, the guide element extending from a proximal portion to a distal portion, wherein the distal portion includes at least one testing electrode, wherein the guide element is advanceable through the angled opening to be deflected laterally away from the catheter at the deflection angle to position the at least one testing electrode proximate the region of the cardiac conduction system in a myocardium of the patient's heart when the distal portion of the catheter is positioned in the coronary sinus;

the implantable lead receivable in the side lumen, the lead comprising a lead body extending from a proximal portion to a distal portion, wherein the implantable lead comprises an anchoring element disposed along the lead body and at least one pacing electrode disposed along the distal portion, wherein the at least one pacing electrode is configured to pace the region of the cardiac conduction system of the patient's heart, wherein the lead is advanceable through the angled opening to be deflected laterally away from the catheter at the deflection angle to implant the at least one pacing electrode proximate the region of the cardiac conduction system in the myocardium of the patient's heart to pace the cardiac conduction system of the patient's heart; and

an electrical analyzer operably coupled to the at least one testing electrode, the electrical analyzer configured to:

provide pacing pulses to a potential implant location when the at least one testing electrode is positioned proximate the region of the cardiac conduction system in the myocardium of the patient's heart and the distal portion of the catheter is positioned in the coronary sinus; and

determine that pacing delivered using the at least one testing electrode has captured the cardiac conduction system at the potential implant location.

12 . The system according to claim 11 , comprising an implantable controller operably coupled to the at least one pacing electrode, the anchoring element, or both, the implantable controller configured to provide pacing pulses to a selected implant location using the at least one pacing electrode.

13 . The system according to claim 11 , further comprising an interventricular ultrasound (IVUS) system configured to monitor the position of the distal portion of the catheter.

14 . The system according to claim 11 , further comprising an electrode apparatus operably coupled to the patient, the electrode apparatus configured to monitor QRS duration in response to pacing the potential implant location using the at least one testing electrode.

15 . The system according to claim 14 , wherein electrical analyzer is configured to determine that pacing delivered using the at least one testing electrode has captured the cardiac conduction system at the potential implant location based on the monitored QRS duration.

16 . The system according to claim 15 , wherein to determine that pacing delivered using the at least one testing electrode has captured the cardiac conduction system at the potential implant location based on the monitored QRS duration, the electrical analyzer is further configured to determine that pacing delivered using the at least one testing electrode has captured the cardiac conduction system at the potential implant location if the monitored QRS duration is below a duration threshold.

17 . The system according to claim 14 , wherein the electrical analyzer is further configured to:

provide pacing pulses to a plurality of different potential implant locations using the at least one testing electrode; and

determine one or more target implant locations of the plurality of different potential implant locations to implant the at least one pacing electrode of the implantable lead based on the monitored QRS duration during the pacing to each of the plurality of different potential implant locations.

18 . The system according to claim 17 , wherein, to determine one or more target implant locations of the plurality of different potential implant locations to implant the at least one pacing electrode of the implantable lead based on the monitored QRS duration during the pacing to each of the plurality of different potential implant locations, the electrical analyzer is configured to identify a target implant location of the plurality of different potential implant locations resulting in a narrowest monitored QRS duration.

19 . The system according to claim 17 , wherein, to determine one or more target implant locations of the plurality of different potential implant locations to implant the at least one pacing electrode of the implantable lead based on the monitored QRS duration during the pacing to each of the plurality of different potential implant locations, the electrical analyzer is configured to identify each of the plurality of different potential implant locations resulting in the monitored QRS duration below a duration threshold as the one or more target implant locations.

20 . The system according to claim 19 , the electrical analyzer is further configured to, in response to identifying more than one of the plurality of different potential implant locations as the one or more target implant locations, select one of the one or more target implant locations based on pacing threshold.

Assignments (1)

Continuity (2)

References Cited (400)