IP Library Granted Patent US 12,472,020
Granted Patent B2
US 12,472,020 · App. 18/510,317 · Granted Nov 18, 2025

Robotically controlled clot manipulation and removal

Inventors: Anne Donahue Doisneau (San Francisco, CA); Alexander Tarek Hassan (San Francisco, CA); Frederic H. Moll (San Francisco, CA)
Assignee: Auris Health, Inc.
A61B34/30A61B17/12136A61B17/3207A61B2017/22038A61B2034/301A61B2034/303A61B2090/08021
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,472,020
App. No.
18/510,317
Filed
Nov 15, 2023
Granted
Nov 18, 2025
Kind
B2
Art Unit
3771
USPC
606/159
Abstract

Certain aspects relate to systems, devices, and techniques for clot manipulation and removal. At least some of the devices for clot manipulation and removal can be robotically controlled. These devices can include one or more elongate members that can be robotically driven through a patient's vasculature. One such device can include a first elongate member that can serve as an access sheath, a second elongate member that can serve as a clot removal catheter, a third elongate member that can serve as a clot disruptor, and a fourth elongate member that can serve as a guidewire.

Claims (16)

1 . A method of clot removal comprising:

driving a robotically controlled instrument system toward a clot within vasculature of a patient, wherein the instrument system comprises a first elongate member and a second elongate member positioned coaxially with the first elongate member, the first elongate member having a greater number of articulation cables than the second elongate member;

piercing the clot using a blunt distal tip of a third elongate member;

reducing the clot to smaller particles using a clot cutter of the third elongate member;

deploying a distal guard along a length of the third elongate member that is downstream from a location of the clot to prevent the smaller particles from being distributed downstream in the patient;

applying a pump of the second elongate member to aspirate the clot; and

capturing the clot using a retriever of the instrument system.

2 . The method of claim 1 , further comprising driving the third elongate member within the vasculature of the patient.

3 . The method of claim 1 , wherein the first elongate member and the second elongate member are driven in tandem.

4 . The method of claim 1 , further comprising displaying, on a display screen, a representation of the vasculature and a representation of the instrument system.

5 . The method of claim 4 , further comprising displaying, on the display screen, an indicator of a concentricity of the instrument system within the vasculature of the patient.

6 . The method of claim 1 , further comprising obtaining, by a processor system, information related to one or more of a location of an occlusion or a severity of blockage by the clot.

7 . The method of claim 1 , the blunt distal tip comprising a blade.

8 . The method of claim 1 , further comprising driving a fourth elongate member within the vasculature of the patient.

9 . The method of claim 8 , the fourth elongate member comprising a guidewire.

10 . The method of claim 1 , further comprising occluding a vessel using an inflatable member of the first elongate member.

Continuity (3)
Division 16748405 · Jan 21, 2020
Provisional Application 62803328 · Feb 8, 2019
Related Publication 20240081928A1 · Mar 14, 2024
References Cited (218)
US 5011488A · Ginsburg · 1991 [cited by applicant]
US 5199417A · Muller · 1993 [cited by applicant]
US 5876325A · Mizuno · 1999 [cited by applicant]
US 5972019A · Engelson · 1999 [cited by examiner]
US 8021326B2 · Moll · 2011 [cited by applicant]
US 8652030B2 · Matsuura · 2014 [cited by applicant]
US 9504604B2 · Alvarez · 2016 [cited by applicant]
US 9561083B2 · Yu · 2017 [cited by applicant]
US 9622827B2 · Yu · 2017 [cited by applicant]
US 9636184B2 · Lee · 2017 [cited by applicant]
US 9668768B2 · Piron · 2017 [cited by applicant]
US 9713509B2 · Schuh · 2017 [cited by applicant]
US 9717563B2 · Tognaccini · 2017 [cited by applicant]
US 9727963B2 · Mintz · 2017 [cited by applicant]
US 9737371B2 · Romo · 2017 [cited by applicant]
US 9737373B2 · Schuh · 2017 [cited by applicant]
US 9744335B2 · Jiang · 2017 [cited by applicant]
US 9763741B2 · Alvarez · 2017 [cited by applicant]
US 9782229B2 · Crawford · 2017 [cited by applicant]
US 9788910B2 · Schuh · 2017 [cited by applicant]
US 9844412B2 · Bogusky · 2017 [cited by applicant]
US 9867635B2 · Alvarez · 2018 [cited by applicant]
US 9918681B2 · Wallace · 2018 [cited by applicant]
US 9931025B1 · Graetzel · 2018 [cited by applicant]
US 9949749B2 · Noonan · 2018 [cited by applicant]
US 9955986B2 · Shah · 2018 [cited by applicant]
US 9962228B2 · Schuh · 2018 [cited by applicant]
US 9980785B2 · Schuh · 2018 [cited by applicant]
US 9993313B2 · Schuh · 2018 [cited by applicant]
US 10016900B1 · Meyer · 2018 [cited by applicant]
US 10022192B1 · Ummalaneni · 2018 [cited by applicant]
US 10080576B2 · Romo · 2018 [cited by applicant]
US 10136959B2 · Mintz · 2018 [cited by applicant]
US 10145747B1 · Lin · 2018 [cited by applicant]
US 10149720B2 · Romo · 2018 [cited by applicant]
US 10159532B1 · Ummalaneni · 2018 [cited by applicant]
US 10159533B2 · Moll · 2018 [cited by applicant]
US 10169875B2 · Mintz · 2019 [cited by applicant]
US 10219874B2 · Yu · 2019 [cited by applicant]
US 10231793B2 · Romo · 2019 [cited by applicant]
US 10231867B2 · Alvarez · 2019 [cited by applicant]
US 10244926B2 · Noonan · 2019 [cited by applicant]
US 10285574B2 · Landey · 2019 [cited by applicant]
US 10299870B2 · Connolly · 2019 [cited by applicant]
US 10314463B2 · Agrawal · 2019 [cited by applicant]
US 10383765B2 · Alvarez · 2019 [cited by applicant]
US 10398518B2 · Yu · 2019 [cited by applicant]
US 10405939B2 · Romo · 2019 [cited by applicant]
US 10405940B2 · Romo · 2019 [cited by applicant]
US 10426559B2 · Graetzel · 2019 [cited by applicant]
US 10426661B2 · Kintz · 2019 [cited by applicant]
US 10434660B2 · Meyer · 2019 [cited by applicant]
US 10464209B2 · Ho · 2019 [cited by applicant]
US 10470830B2 · Hill · 2019 [cited by applicant]
US 10482599B2 · Mintz · 2019 [cited by applicant]
US 10493241B2 · Jiang · 2019 [cited by applicant]
US 10500001B2 · Yu · 2019 [cited by applicant]
US 10517692B2 · Eyre · 2019 [cited by applicant]
US 10524866B2 · Srinivasan · 2020 [cited by applicant]
US 10539478B2 · Lin · 2020 [cited by applicant]
US 10639114B2 · Schuh · 2020 [cited by applicant]
US 10646291B2 · Turner · 2020 [cited by applicant]
US 10765487B2 · Ho · 2020 [cited by applicant]
US 11857277B2 · Doisneau et al. · 2024 [cited by applicant]
US 20020082612A1 · Moll · 2002 [cited by applicant]
US 20030181809A1 · Hall · 2003 [cited by applicant]
US 20040176751A1 · Weitzner · 2004 [cited by applicant]
US 20050222554A1 · Wallace · 2005 [cited by examiner]
US 20060058617A1 · Sano · 2006 [cited by applicant]
US 20060178556A1 · Hasser · 2006 [cited by applicant]
US 20070013336A1 · Nowlin · 2007 [cited by applicant]
US 20070197896A1 · Moll · 2007 [cited by applicant]
US 20070299456A1 · Teague · 2007 [cited by applicant]
US 20080082109A1 · Moll · 2008 [cited by examiner]
US 20080147089A1 · Loh · 2008 [cited by applicant]
US 20090005768A1 · Sharareh · 2009 [cited by applicant]
US 20090048611A1 · Funda · 2009 [cited by applicant]
US 20090326318A1 · Tognaccini · 2009 [cited by applicant]
US 20100100045A1 · Pravongviengkham · 2010 [cited by applicant]
US 20100234857A1 · Itkowitz · 2010 [cited by applicant]
US 20110184241A1 · Zubiate · 2011 [cited by applicant]
US 20110277775A1 · Holop · 2011 [cited by applicant]
US 20120283747A1 · Popovic · 2012 [cited by applicant]
US 20120302869A1 · Koyrakh · 2012 [cited by applicant]
US 20130218005A1 · Desai · 2013 [cited by applicant]
US 20140051049A1 · Jarc · 2014 [cited by applicant]
US 20140142591A1 · Alvarez · 2014 [cited by applicant]
US 20140243801A1 · Fanelli · 2014 [cited by applicant]
US 20140276913A1 · Tah · 2014 [cited by applicant]
US 20140357984A1 · Wallace · 2014 [cited by applicant]
US 20140364870A1 · Alvarez · 2014 [cited by applicant]
US 20150025549A1 · Kilroy · 2015 [cited by applicant]
US 20150045675A1 · Chernomorsky · 2015 [cited by applicant]
US 20150088161A1 · Hata · 2015 [cited by applicant]
US 20150164596A1 · Romo · 2015 [cited by applicant]
US 20150223832A1 · Swaney · 2015 [cited by applicant]
US 20150297299A1 · Yeung · 2015 [cited by applicant]
US 20150305650A1 · Hunter · 2015 [cited by applicant]
US 20160001038A1 · Romo · 2016 [cited by applicant]
US 20160228202A1 · Prindiville · 2016 [cited by examiner]
US 20160270865A1 · Landey · 2016 [cited by applicant]
US 20160287279A1 · Bovay · 2016 [cited by applicant]
US 20170007337A1 · Dan · 2017 [cited by applicant]
US 20170071456A1 · Ratnakar · 2017 [cited by applicant]
US 20170095299A1 · Hendrick · 2017 [cited by applicant]
US 20170119413A1 · Romo · 2017 [cited by examiner]
US 20170119481A1 · Romo · 2017 [cited by applicant]
US 20170135710A1 · Hasegawa · 2017 [cited by applicant]
US 20170135833A1 · Syed · 2017 [cited by applicant]
US 20170143442A1 · Tesar · 2017 [cited by applicant]
US 20170165011A1 · Bovay · 2017 [cited by applicant]
US 20170189118A1 · Chopra · 2017 [cited by applicant]
US 20170189131A1 · Weir · 2017 [cited by applicant]
US 20170202627A1 · Sramek · 2017 [cited by applicant]
US 20170209073A1 · Sramek · 2017 [cited by applicant]
US 20170290631A1 · Lee · 2017 [cited by applicant]
US 20170340396A1 · Romo · 2017 [cited by applicant]
US 20170367782A1 · Schuh · 2017 [cited by applicant]
US 20180025666A1 · Ho · 2018 [cited by applicant]
US 20180098817A1 · Nichogi · 2018 [cited by applicant]
US 20180177556A1 · Noonan · 2018 [cited by applicant]
US 20180214011A1 · Graetzel · 2018 [cited by applicant]
US 20180221038A1 · Noonan · 2018 [cited by applicant]
US 20180221039A1 · Shah · 2018 [cited by applicant]
US 20180250083A1 · Schuh · 2018 [cited by applicant]
US 20180271616A1 · Schuh · 2018 [cited by applicant]
US 20180279852A1 · Rafii-Tari · 2018 [cited by applicant]
US 20180280660A1 · Landey · 2018 [cited by applicant]
US 20180289431A1 · Draper · 2018 [cited by applicant]
US 20180325499A1 · Landey · 2018 [cited by applicant]
US 20180333044A1 · Jenkins · 2018 [cited by applicant]
US 20180338799A1 · Hladio · 2018 [cited by applicant]
US 20180360435A1 · Romo · 2018 [cited by applicant]
US 20180360479A1 · Hofmann · 2018 [cited by examiner]
US 20180368920A1 · Ummalaneni · 2018 [cited by applicant]
US 20190000559A1 · Berman · 2019 [cited by applicant]
US 20190000560A1 · Berman · 2019 [cited by applicant]
US 20190000576A1 · Mintz · 2019 [cited by applicant]
US 20190083183A1 · Moll · 2019 [cited by applicant]
US 20190110839A1 · Rafii-Tari · 2019 [cited by applicant]
US 20190110843A1 · Ummalaneni · 2019 [cited by applicant]
US 20190151148A1 · Alvarez · 2019 [cited by applicant]
US 20190167366A1 · Ummalaneni · 2019 [cited by applicant]
US 20190175009A1 · Mintz · 2019 [cited by applicant]
US 20190175062A1 · Rafii-Tari · 2019 [cited by applicant]
US 20190175799A1 · Hsu · 2019 [cited by applicant]
US 20190183585A1 · Rafii-Tari · 2019 [cited by applicant]
US 20190183587A1 · Rafii-Tari · 2019 [cited by applicant]
US 20190216548A1 · Ummalaneni · 2019 [cited by applicant]
US 20190216576A1 · Eyre · 2019 [cited by applicant]
US 20190223974A1 · Romo · 2019 [cited by applicant]
US 20190228525A1 · Mintz · 2019 [cited by applicant]
US 20190246882A1 · Graetzel · 2019 [cited by applicant]
US 20190262086A1 · Connolly · 2019 [cited by applicant]
US 20190269468A1 · Hsu · 2019 [cited by applicant]
US 20190274764A1 · Romo · 2019 [cited by applicant]
US 20190290109A1 · Agrawal · 2019 [cited by applicant]
US 20190298160A1 · Ummalaneni · 2019 [cited by applicant]
US 20190298460A1 · Al-Jadda · 2019 [cited by applicant]
US 20190298465A1 · Chin · 2019 [cited by applicant]
US 20190328213A1 · Landey · 2019 [cited by applicant]
US 20190336238A1 · Yu · 2019 [cited by applicant]
US 20190365201A1 · Noonan · 2019 [cited by applicant]
US 20190365209A1 · Ye · 2019 [cited by applicant]
US 20190365479A1 · Rafii-Tari · 2019 [cited by applicant]
US 20190365486A1 · Srinivasan · 2019 [cited by applicant]
US 20190374297A1 · Wallace · 2019 [cited by applicant]
US 20190375383A1 · Auer · 2019 [cited by applicant]
US 20190380787A1 · Ye · 2019 [cited by applicant]
US 20190380797A1 · Yu · 2019 [cited by applicant]
US 20200000530A1 · DeFonzo · 2020 [cited by applicant]
US 20200000533A1 · Schuh · 2020 [cited by applicant]
US 20200022767A1 · Hill · 2020 [cited by applicant]
US 20200038123A1 · Graetzel · 2020 [cited by applicant]
US 20200039086A1 · Meyer · 2020 [cited by applicant]
US 20200046434A1 · Graetzel · 2020 [cited by applicant]
US 20200054408A1 · Schuh · 2020 [cited by applicant]
US 20200060516A1 · Baez, Jr. · 2020 [cited by applicant]
US 20200085516A1 · DeFonzo · 2020 [cited by applicant]
US 20200093549A1 · Chin · 2020 [cited by applicant]
US 20200093554A1 · Schuh · 2020 [cited by applicant]
US 20200100845A1 · Julian · 2020 [cited by applicant]
US 20200100855A1 · Leparmentier · 2020 [cited by applicant]
US 20200101264A1 · Jiang · 2020 [cited by applicant]
US 20200107894A1 · Wallace · 2020 [cited by applicant]
US 20200121502A1 · Kintz · 2020 [cited by applicant]
US 20200146769A1 · Eyre · 2020 [cited by applicant]
US 20200170720A1 · Ummalaneni · 2020 [cited by applicant]
US 20200171660A1 · Ho · 2020 [cited by applicant]
US 20200188043A1 · Yu · 2020 [cited by applicant]
US 20200197112A1 · Chin · 2020 [cited by applicant]
US 20200206472A1 · Ma · 2020 [cited by applicant]
US 20200217733A1 · Lin · 2020 [cited by applicant]
US 20200222134A1 · Schuh · 2020 [cited by applicant]
US 20200237458A1 · DeFonzo · 2020 [cited by applicant]
US 20200261172A1 · Romo · 2020 [cited by applicant]
US 20200268459A1 · Noonan · 2020 [cited by applicant]
US 20200268460A1 · Tse · 2020 [cited by applicant]
US 20200281787A1 · Ruiz · 2020 [cited by applicant]
EP 0347098B1 · 1996 [cited by applicant]
EP 2737922A1 · 2014 [cited by applicant]
EP 1906858B1 · 2016 [cited by applicant]
EP 3335647A2 · 2018 [cited by applicant]
EP 3417901A1 · 2018 [cited by applicant]
WO 2017048194A1 · 2017 [cited by applicant]
WO 2019005992A1 · 2019 [cited by applicant]
Darwiche, Fadi, et al.; “Operative Technique and Early Experience for Robotic Assisted Laparoscopic Nephroureterectomy (RALNU) Using da Vinci XI”, SpringerPlus; 2015; 5 pages. [cited by applicant]
Sasaki, Kazuhito, et al.; “Laparoscopic Hemicolectomy for a Patient with Situs Inversus Totalis: A Case Report”; International Journal of Surgery Case Reports; Oct. 16, 2017; 4 pages. [cited by applicant]
PCT International Search Report and PCT Written Opinion of the International Searching Authority; Application No. PCT/US2020/014438; Mar. 11, 2020; 9 pages. [cited by applicant]
Office Action dated Apr. 5, 2021; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 6 pages. [cited by applicant]
Office Action dated Jun. 9, 2021; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 19 pages. [cited by applicant]
Office Action dated Apr. 4, 2022; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 12 pages. [cited by applicant]
Final Office Action dated Oct. 24, 2022; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 14 pages. [cited by applicant]
Advisory Action dated Mar. 9, 2023; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 4 pages. [cited by applicant]
Office Action dated Apr. 26, 2023; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 19 pages. [cited by applicant]
Notice of Allowance dated Aug. 17, 2023; U.S. Appl. No. 16/748,405, filed Jan. 21, 2020; 9 pages. [cited by applicant]
Extended European Search Report; Application No. 20752046.1; Oct. 19, 2022; 15 pages. [cited by applicant]
European Communication dated Feb. 27, 2025, for Application No. 20752046.1, 7 pages. [cited by applicant]