Granted Patent B2

US 12,515,005 · App. 17/813,450 · Granted Jan 6, 2026

Inventors: Dean Hafeman (Greenleaf, WI); Seongsik Chang (Santa Clara, CA)

Assignee: Health Micro Devices

A61M16/1075A61M16/0006A61M16/06A61M16/16A61M16/205A61M2016/0018A61M2205/0294A61M2205/3327A61M2205/3368A61M2230/42

Abstract

Claims (83)

1 . A self-contained system comprising:

a mask enclosure comprised of breathable fabric that, when worn by a user, is adapted to flexibly conform to the face of the user to form a cavity between the mask enclosure and the face that includes the mouth and nose of the user,

wherein the mask enclosure comprises outer and inner layers of the breathable fabric, and

wherein when the mask enclosure is worn by the user, the inner layer defines a periphery of the cavity and the outer layer is exposed to ambient air outside the cavity;

a reservoir in which liquid is stored,

wherein the reservoir is attached to, and supported by, the mask enclosure; and

a dispensing mechanism that includes—

a sensor configured to generate measurements that are representative of a characteristic of air that is exhaled through the nostrils or mouth of the user,

a controller configured to generate a signal in response to determining, in real time based on analysis of the measurements, that an exhalation phase has ended, and

a droplet generator configured to

initiate, in response to receiving the signal from the controller, dispensation of the liquid from the reservoir into the cavity in the form of droplets,

wherein dispensation begins when an inhalation phase commences, so as to humidify air drawn into the nostrils or mouth during the inhalation phase, and

wherein dispensation ends before the inhalation phase concludes, such that dispensation occurs over only an initial portion of the inhalation phase,

wherein the droplet generator is attached directly to the reservoir so that the droplet generator and the reservoir are supported by the mask enclosure.

2 . The self-contained system of claim 1 ,

wherein the droplet generator includes

(i) a plate with

a first side that has one or more ingress holes through which the liquid is able to enter the plate, and

a second side that has one or more egress holes through which the liquid is able to exit the plate,

wherein the one or more ingress holes on the first side are fluidly connected to the one or more egress holes on the second side, and

(ii) a vibration element configured to induce movement of the liquid through the plate through ultrasonic vibration, and

wherein the droplets are less than 1 nanoliter in volume.

3 . The self-contained system of claim 1 ,

wherein the sensor is an accelerometer that is connected to a flap situated in an exhaust valve in the breathable fabric of the mask enclosure, and

wherein the accelerometer measures motion of the flap, the motion being indicative of whether air is presently being exhaled through the nostrils or mouth of the user.

4 . The self-contained system of claim 1 ,

wherein the sensor is an accelerometer that is mounted to a flexible membrane embedded in the mask enclosure, and

wherein the accelerometer is configured to generate measurements that are indicative of motion of the flexible membrane.

5 . The self-contained system of claim 1 , wherein the reservoir additionally comprises a concentrated reagent that is separated from the liquid that acts as a diluent.

6 . The self-contained system of claim 5 , wherein the concentrated reagent comprises amounts of elemental iodine, iodide anion, or tri-iodide anion (I 3 − ).

7 . The self-contained system of claim 6 , wherein upon mixing the concentrated reagent and the liquid, the resulting mixture is a solution comprising between 5 nanomolar and 5 micromolar concentrations of elemental iodine, iodide anion, or tri-iodide anion (I 3 − ).

8 . The self-contained system of claim 1 , wherein a volume of liquid stored by the reservoir is no greater than 100 milliliters.

9 . The self-contained system of claim 1 ,

wherein the sensor is an accelerometer that is mounted to a flexible membrane embedded in the mask enclosure,

wherein the flexible membrane is in contact with the cavity, and

wherein the accelerometer monitors motion of the flexible membrane that is caused by reversals in direction of airflow through the nostrils of the user.

10 . The self-contained system of claim 1 , wherein a weight of the self-contained system is less than 100 grams.

11 . The self-contained system of claim 1 , wherein the droplets are dispensed over the initial portion of the inhalation phase at a frequency of at least 100 kilohertz.

12 . The self-contained system of claim 1 ,

wherein the sensor is a temperature sensor that is located along an interior surface of the mask enclosure, and

wherein the temperature sensor measures temperature of air inside the cavity of the mask enclosure, the temperature being indicative of whether air is presently being exhaled through the nostrils or mouth of the user.

13 . The self-contained system of claim 12 , further comprising:

a second temperature sensor that is located along an exterior surface of the mask enclosure,

wherein the second temperature sensor measures temperature of ambient air outside the cavity of the mask enclosure.

14 . The self-contained system of claim 13 ,

wherein ambient temperature measurements generated by the second temperature sensor are provided to the controller as input, and

wherein the controller is further configured to establish a present phase of a breathing cycle based on a comparison of cavity temperature measurements generated by the temperature sensor and ambient temperature measurements generated by the second temperature sensor.

15 . The self-contained system of claim 1 ,

wherein the droplet generator includes an array of piezoelectric actuators, and

wherein each piezoelectric actuator includes (i) a chamber in which liquid is contained, (ii) a nozzle, and (iii) a piezoelectric element that is configured to displace the liquid in the chamber when a suitable voltage is applied thereto, thereby causing the liquid to be dispensed through the nozzle in the form of a droplet, and

wherein the droplets are less than 1 nanoliter in volume.

16 . The self-contained system of claim 1 ,

wherein the droplet generator includes an array of thermal actuators, and

wherein each thermal actuator includes (i) a chamber in which liquid is contained, (ii) a nozzle, and (iii) a heating element that is configured to heat the liquid to boiling, thereby causing a bubble to form that forces the liquid to be dispensed through the nozzle in the form of a droplet.

17 . The self-contained system of claim 16 , wherein the thermal actuators in the array are operated sequentially so that droplets are dispensed at a predetermined interval.

18 . The self-contained system of claim 17 , wherein the predetermined interval is less than 5 microseconds.

19 . The self-contained system of claim 1 , further comprising:

a rechargeable power source to which the droplet generator is electrically connected.

20 . A self-contained system comprising:

a mask enclosure comprised of outer and inner fabric layers that, when worn by a user, is adapted to flexibly conform to the face of the user to form a cavity that includes the mouth and nose of the user,

wherein when the mask enclosure is worn by the user, the inner fabric layer defines a periphery of the cavity and the outer fabric layer is exposed to ambient air outside the cavity;

a dispensing mechanism that is attached to, and supported by, the mask enclosure,

wherein the dispensing mechanism includes:

(i) a reservoir in which liquid is stored,

(ii) a droplet generator that is in fluid communication with the reservoir,

(iii) a respiratory cycle detector that includes a sensor able to monitor a breathing cycle of the user, and

(iv) a controller that is in electronic communication with the respiratory cycle detector and the droplet generator, and

wherein the dispensing mechanism provides for dispensation of droplets into the cavity in response to measurements made by the sensor of the respiratory cycle detector,

wherein the measurements are representative of a characteristic of air that is exhaled through the mouth or nose of the user, and

wherein dispensation of the droplets begins when an inhalation phase of the breathing cycle of the user commences, so as to humidify air drawn into the mouth or nose during the inhalation phase.

21 . The self-contained system of claim 20 , wherein the droplet generator includes

(i) a plate with

a first side that has one or more ingress holes through which the liquid is able to enter the plate, and

a second side that has one or more egress holes through which the liquid is able to exit the plate,

wherein the one or more ingress holes on the first side are fluidly connected to the one or more egress holes on the second side, and

(ii) a vibration element configured to induce movement of the liquid through the plate through ultrasonic vibration, and

wherein the droplets are less than 1 nanoliter in volume.

22 . The self-contained system of claim 20 ,

wherein the sensor is an accelerometer that is connected to a flap situated in an exhaust valve in the outer and inner fabric layers of the mask enclosure, and

wherein the accelerometer measures motion of the flap, the motion being indicative of whether air is presently being exhaled through the mouth or nose of the user.

23 . The self-contained system of claim 20 ,

wherein the sensor is an accelerometer that is mounted to a flexible membrane embedded in the mask enclosure, and

wherein the accelerometer is configured to generate measurements that are indicative of motion of the flexible membrane.

Assignments (1)

Continuity (2)

References Cited (32)