Device with features for rotational atherectomy and lithotripsy
Some embodiments of a rotational atherectomy and lithotripsy system can partially or completely remove a stenotic lesion in blood vessels by rotating one or more abrasive elements to abrade and breakdown the lesion, by emitting acoustic energy to fracture and breakdown the lesion, or a combination of both.
1 . A device for removing stenotic lesion material from an artery of a patient, the device comprising:
an elongated flexible drive shaft defining a longitudinal axis and comprising a torque-transmitting coil of one or more filars;
eccentric abrasive burrs fixedly mounted on a distal end portion of the torque-transmitting coil; and
one or more lithotripsy emitters fixedly mounted on the distal end portion of the torque-transmitting coil, each of the lithotripsy emitters configured to selectively emit acoustic energy.
2 . The device of claim 1 , wherein at least one of the lithotripsy emitters is mounted to the torque-transmitting coil between two of the eccentric abrasive burrs.
3 . The device of claim 1 , wherein the eccentric abrasive burrs are coated with an abrasive media having a first grit.
4 . The device of claim 3 , wherein the lithotripsy emitters are coated with the abrasive media having the first grit.
5 . The device of claim 3 , wherein the lithotripsy emitters are coated with the abrasive media having a second grit.
6 . The device of claim 3 , wherein the lithotripsy emitters have a nonabrasive exterior surface.
7 . The device of claim 3 , wherein each of the lithotripsy emitters have a center of mass concentric with the longitudinal axis.
8 . The device of claim 1 , wherein each of the eccentric abrasive burrs has a center of mass offset from the longitudinal axis of elongated flexible drive shaft.
9 . The device of claim 1 , wherein the one or more filars of the torque-transmitting coil comprise:
a first filar electrically coupled to anodes of each of the lithotripsy emitters;
a second filar electrically coupled to cathodes of the lithotripsy emitters.
10 . The device of claim 9 , wherein the first filar is electrically insulated from the second filar.
11 . The device of claim 1 , wherein the device further comprises a pump for pumping conductive fluid into a balloon to inflate the balloon.
12 . The device of claim 11 , wherein the conductive fluid comprises saline and a contrast media.
13 . A rotational atherectomy and lithotripsy device, comprising:
an elongated flexible drive shaft defining a longitudinal axis and comprising a torque-transmitting coil of one or more filars;
one or more abrasive burrs fixedly mounted on a distal end portion of the torque-transmitting coil; and
one or more lithotripsy emitters configured to selectively emit acoustic energy and positioned proximate to the one or more abrasive burrs such that all of the one or more abrasive burrs and the one or more lithotripsy emitters are longitudinally advanceable together with the elongated flexible drive shaft.
14 . The device of claim 13 , wherein the one or more lithotripsy emitters are fixedly mounted on the distal end portion of the torque-transmitting coil such that all of the one or more abrasive burrs and the one or more lithotripsy emitters are longitudinally advanceable together with the elongated flexible drive shaft.
15 . The device of claim 13 , further comprising a sheath that surrounds at least a portion of the elongated flexible drive shaft and that carries an expandable balloon at a distal end of the sheath encapsulating the one or more lithotripsy emitters.
16 . The device of claim 15 , wherein the sheath and the drive shaft are configured to advance together over a guidewire, and the one or more lithotripsy emitters are fixedly mounted on the sheath such that all of the one or more abrasive burrs and the one or more lithotripsy emitters are longitudinally advanceable together with the elongated flexible drive shaft.
17 . The device of claim 13 , wherein the device further comprises a pump for pumping conductive fluid into the balloon to inflate the balloon.
18 . The device of claim 17 , wherein the conductive fluid comprises saline and a contrast media.
19 . A device configured to apply both rotational atherectomy and lithotripsy, comprising:
a control handle assembly;
a torque-transmitting coil extending distally from the control handle assembly;
one or more abrasive burrs fixedly mounted on a distal end portion of the torque-transmitting coil; and
one or more lithotripsy emitters positioned proximate to the one or more abrasive burrs, wherein the control handle assembly is configured to activate rotation of the one or more abrasive burrs at a targeted arterial site and to activate the one or more lithotripsy emitters to output acoustic energy at the targeted arterial site.
20 . The device of claim 19 , wherein:
at least one of the one or more lithotripsy emitters is mounted to the torque-transmitting coil proximate to at least one of the one or more abrasive burrs,
the one or more abrasive burrs and the one or more lithotripsy emitters are coated with an abrasive media having a first grit, and
the one or more filars of the torque-transmitting coil comprise:
a first filar electrically coupled to anodes of each of the lithotripsy emitters; and
a second filar electrically coupled to cathodes of the lithotripsy emitters,
wherein the first filar is electrically insulated from the second filar.