IP Library Granted Patent US 12,642,913
Granted Patent B2
US 12,642,913 · App. 18/819,222 · Granted Jun 2, 2026

Medicament delivery device

Inventors: Timothy Denyer (Melbourn, GB); James Bradford (Melbourn, GB); Alexander Hee-Hanson (Melbourn, GB); Robert Wilson (Melbourn, GB); Dean Twite (Melbourn, GB); Thomas Lever (Melbourn, GB)
Assignee: Genzyme Corporation
A61M5/3204
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Quick Facts
Patent No.
US 12,642,913
App. No.
18/819,222
Granted
Jun 2, 2026
Kind
B2
Abstract

A medicament delivery device has a needle for injecting medicament into a user, a body having a proximal end and a distal end and a needle cover. The needle cover is axially movable relative to the body between an initial position, in which the needle cover covers the distal end of the needle, and a holding position. In the holding position the needle protrudes from the distal end of the needle cover. The needle cover has a flexible arm. The device further has a needle cover guide comprising a track. The flexible arm engages the track. The track has a radially-extending ramp configured to flex the flexible arm when the needle cover moves from the initial position to the holding position. The flexible arm is flexed when the needle cover is in the holding position.

Claims (27)

1 . A medicament delivery device comprising:

a needle for injecting medicament;

a body having a proximal end and a distal end;

a needle cover, wherein the needle cover is proximally movable relative to the body A between an initial position, in which the needle cover covers a distal end of the needle, and a holding position for dispensing medicament from the device, wherein in the holding position the A needle protrudes from a distal end of the needle cover, wherein the needle cover comprises a flexible arm;

a biasing member configured to bias the needle cover distally; and

a needle cover guide rotatable relative to the body, the needle cover guide comprising a track comprising a first region and a second region, wherein the second region extends at least a first distance partially around a circumference of the needle cover guide for rotating the needle cover guide when the needle cover moves from the initial position to the holding position,

wherein the flexible arm engages the track, and wherein the track comprises a radially-extending ramp configured to flex the flexible arm when the needle cover moves from the initial position to the holding position, and wherein the flexible arm is flexed when the needle cover is in the holding position;

wherein the needle cover is distally movable relative to the body to a locked position, wherein the needle cover covers the distal end of the needle in the locked position, wherein the medicament delivery device comprises a locking surface, and wherein the needle cover engages the locking surface when the needle cover is in the locked position for preventing proximal movement of the needle cover, wherein the locking surface comprises a radially-extending surface extending at least a second distance partially around the circumference of the needle cover guide, wherein the second distance is greater than half of the first distance.

2 . The medicament delivery device of claim 1 , wherein the flexible arm comprises a protrusion, and wherein the flexible arm engages the track via the protrusion.

3 . The medicament delivery device of claim 2 , wherein the protrusion travels from the first region to the second region when the needle cover moves from the initial position to the holding position.

4 . The medicament delivery device of claim 3 , wherein the first region comprises the radially-extending ramp.

5 . The medicament delivery device of claim 3 , wherein the second region is at an acute angle relative to the axis of the device.

6 . The medicament delivery device of claim 1 , wherein the locking surface is provided on the needle cover guide.

7 . The medicament delivery device of claim 1 , wherein the track comprises an axially-extending region, and wherein the flexible arm engages the axially-extending region when the needle cover moves from the holding position to the locked position.

8 . The medicament delivery device of claim 1 , wherein the medicament delivery device is configured to inject greater than 2 ml of medicament.

9 . The medicament delivery device of claim 1 , wherein the medicament delivery device is configured to inject medicament having a viscosity of greater than 25 cP.

10 . The medicament delivery device of claim 1 , wherein the radially-extending ramp is configured to flex the flexible arm radially outwards.

11 . The medicament delivery device of claim 1 , wherein the medicament delivery device comprises the medicament.

12 . The medicament delivery device of claim 1 , wherein the first region extends at least partially around the circumference of the needle cover guide.

13 . The medicament delivery device of claim 1 , wherein the second region comprises a radially-extending ramp.

14 . A method of using a medicament delivery device prior to dispensing medicament from the device, the method comprising moving a needle cover of the device proximally relative to a body of the device towards a holding position, wherein the needle cover comprises a flexible arm which engages a track of the body, the track comprising a first region and a second region, wherein the first region comprises a radially-extending ramp, wherein the second region extends at least a first distance partially around a circumference of the body for rotating the body when the needle cover moves from an initial position to the holding position, and wherein when the needle cover is moved towards the holding position then the flexible arm is flexed by the radially-extending ramp, wherein the needle cover moves to a locked position when the device is removed from the injection site, wherein the medicament delivery device comprises a locking surface, wherein the needle cover engages the locking surface when the needle cover is in the locked position for preventing proximal movement of the needle cover, wherein the locking surface comprises a radially-extending surface extending at least a second distance partially around the circumference of the needle cover guide, wherein the second distance is greater than half of the first distance.

15 . A method of using a medicament delivery device, the method comprising:

pressing a needle cover of the device against an injection site to move the needle cover towards a holding position, wherein the needle cover comprises a flexible arm which engages a rotatable body of the medicament delivery device, wherein the rotatable body comprises a track, the track comprising a first region and a second region, wherein the first region comprises a radially-extending ramp, wherein the second region extends at least a first distance partially around a circumference of the rotatable body for rotating the rotatable body when the needle cover moves from an initial position to the holding position, and wherein the flexible arm is flexed by the radially-extending ramp when the needle cover is moved towards the holding position; and

applying a holding force to the device to hold the needle cover against the injection site whilst medicament is dispensed from the device, wherein the flexible arm is flexed when the holding force is applied to the device; and

removing the device from the injection site, wherein the needle cover moves to a locked position when the device is removed from the injection site, wherein the medicament delivery device comprises a locking surface, wherein the needle cover engages the locking surface when the needle cover is in the locked position for preventing proximal movement of the needle cover, wherein the locking surface comprises a radially-extending surface extending at least a second distance partially around the circumference of the needle cover guide, wherein the second distance is greater than half of the first distance.

16 . The method of claim 15 , wherein the method first comprises removing a cap from the medicament delivery device.

17 . The method of claim 15 , wherein the first region comprises a barrier for engaging the protrusion to prevent or restrict rotation of the needle cover guide when the protrusion travels along the radially-extending ramp.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2025
From: DENYER, TIMOTHY; BRADFORD, JAMES; HEE-HANSON, ALEXANDER; WILSON, ROBERT; TWITE, DEAN; LEVER, THOMAS
To: PA HOLDINGS LIMITED
Reel/Frame 070451/0939 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2025
From: PA HOLDINGS LIMITED
To: PA CONSULTING SERVICES LIMITED
Reel/Frame 070452/0032 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2025
From: PA CONSULTING SERVICES LIMITED
To: SANOFI-AVENTIS DEUTSCHLAND GMBH
Reel/Frame 070452/0079 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2025
From: SANOFI-AVENTIS DEUTSCHLAND GMBH
To: GENZYME CORPORATION
Reel/Frame 070452/0130 →
Continuity (1)
Related Publication 20260061137A1 · Mar 5, 2026
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