IP Library › Granted Patent US 12,648,902
Granted Patent B2
US 12,648,902 · App. 18/275,364 · Granted Jun 9, 2026

Fermented apple composition

Inventors: Kyung Chan Jeon (Seoul, KR); Hee Kyoung Jung (Seoul, KR); Sunhee Kim (Seoul, KR); Yeeun Park (Seoul, KR); Eunyong Lee (Seoul, KR)
Assignee: CJ CHEILJEDANG CORPORATION
A61K8/9789A61K36/73A61P17/16A61Q19/08C12J1/00A61K2236/19A61K2800/782A61K2800/85
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,648,902
App. No.
18/275,364
Granted
Jun 9, 2026
Kind
B2
Abstract

Provided are a fermented apple composition having an effect of reducing or inhibiting UV-induced collagenase expression, and use thereof in the skin improvement and in the prevention or inhibition of skin photoaging.

Claims (15)

1 . A fermented apple composition having an effect of reducing or inhibiting UV-induced collagenase expression,

wherein the fermented apple composition consists of a fermented product produced by fermentation of an apple concentrate and purified water with yeast and acetic acid bacteria.

2 . The fermented apple composition of claim 1 , wherein the collagenase is MMP-1.

3 . The fermented apple composition of claim 1 , wherein the fermented apple composition has an effect of improving the skin.

4 . The fermented apple composition of claim 1 , wherein the fermented apple composition has an effect of preventing skin aging.

5 . The fermented apple composition of claim 4 , wherein the aging is photoaging.

6 . The fermented apple composition of claim 1 , wherein the fermented apple composition has an effect of inhibiting UV-induced collagen degradation.

7 . The fermented apple composition of claim 1 , wherein the fermented apple composition reduces or inhibits the UV-induced collagenase expression by 10% or more when UV-irradiated cells are treated therewith, as compared to UV-irradiated cells without treatment with the fermented apple composition.

8 . The fermented apple composition of claim 1 , wherein the fermented apple composition has an effect of inhibiting UV-induced wrinkle formation.

9 . A food comprising the fermented apple composition of claim 1 .

10 . The food of claim 9 , wherein the food is for improving or enhancing skin health.

11 . A health functional food comprising the fermented apple composition of claim 1 .

12 . The health functional food of claim 11 , wherein the health functional food is for improving or enhancing skin health.

13 . A cosmetic composition comprising the fermented apple composition of claim 1 .

14 . The cosmetic composition of claim 13 , wherein the cosmetic composition is for relaxing or improving skin wrinkles.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2023
From: JEON, KYUNG CHAN; JUNG, HEE KYOUNG; KIM, SUNHEE; PARK, YEEUN; LEE, EUNYONG
To: CJ CHEILJEDANG CORPORATION
Reel/Frame 064660/0325 →
Priority Claims (1)
KR 10-2022-0094864 · Jul 29, 2022 · national
Continuity (1)
Related Publication 20250144004A1 · May 8, 2025
References Cited (16)
US 20190142045A1 · Baek · 2019 [cited by examiner]
JP 2013180958A · 2013 [cited by applicant]
KR 100911108B1 · 2009 [cited by applicant]
KR 101227366B1 · 2013 [cited by applicant]
KR 1020140052127A · 2014 [cited by applicant]
KR 1020160044642A · 2016 [cited by applicant]
KR 1020200038724A · 2020 [cited by applicant]
KR 20200038724A · 2020 [cited by examiner]
Extended European Search Report issued May 6, 2024 for European Patent Application No. 22908856.2. [cited by applicant]
Liminjer et al., “Current and Research Progress in Apple vinegar”, Gansu Agr. Sci. and Techn., No. 7, Jul. 2018, pp. 83-87. [cited by applicant]
Office Action issued in corresponding Chinese Patent Application No. 202280011094.5, dated Jun. 19, 2025. [cited by applicant]
Office Action issued in corresponding Japanese Patent Application No. 2023-542803, dated Sep. 3, 2024. [cited by applicant]
Office Action issued in corresponding Japanese Patent Application No. 2023-542803, dated Mar. 18, 2025. [cited by applicant]
Zhang et al., “Polyphenols in fermented apple juice: Beneficial effects on human health,” Journal of Functional Foods, 76, 104294: 1-16 (2021). [cited by applicant]
Lee et al., “Photo-aging regulation effects of newly bred Green ball apple,” Journal of Applied Biological Chemistry, 63 (1): 75-82 (2020). [cited by applicant]
International Search Report issued in corresponding International Patent Application No. PCT/KR2022/019571 dated Apr. 24, 2023. [cited by applicant]