IP Library › Granted Patent US 12,712,061
Granted Patent B2
US 12,712,061 · App. 19/074,288 · Granted Aug 18, 2026

Distributed ledger for medicament administration tracking

Inventors: Patrick Soon-Shiong (Los Angeles, CA); Nicholas J. Witchey (Laguna Hills, CA)
Assignee: ImmunityBio, Inc.
G16H20/13G07C9/00182G07C9/00896
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Quick Facts
Patent No.
US 12,712,061
App. No.
19/074,288
Filed
Mar 7, 2025
Granted
Aug 18, 2026
Kind
B2
Art Unit
3682
USPC
705/2
Abstract

An autonomous tracking system receives a request to administer a patient-specific therapeutic comprising a scanned identifier associated with a labeled dual chamber device (DCD) including a first chamber having one or more lyophilized components, a second chamber having a reconstitution buffer, and a locking mechanism for controlling access to the DCD chambers. A tracking engine queries an administration database based on the scanned identifier to find a notarized ledger associated with the DCD and retrieves a blockchain entry comprising a first distributed ledger transaction identifying the one or more lyophilized components and a digital token associated with an owner of the labeled DCD. After the owner is authenticated, a second distributed transaction is created identifying the one or more lyophilized components as being authorized for administration to the patient. In response, autonomous access to the one or more lyophilized components unlocks the locking mechanism to administer the medication.

Claims (27)

1 . A computer-based system for managing a dual chamber device (DCD) using non-fungible tokens (NFTs), the system comprising:

at least one dual chamber device (DCD) comprising a first chamber having one or more lyophilized components and a second chamber having a reconstitution buffer;

at least one memory storing software instructions and at least one notarized ledger; and

at least one processor coupled with the at least one memory and that upon execution of the software instructions performs the following operations:

minting an NFT on the at least one notarized ledger and representing the DCD;

updating a state of the NFT on the at least one notarized ledger throughout a lifecycle of the DCD, wherein the lifecycle of the DCD includes receiving an administration request from a user, authenticating the administration request of the user, and authorizing administration of the one or more lyophilized components;

upon administration authorization, unlocking one or more of the first chamber or the second chamber to administer contents of the DCD; and

burning the NFT after administration of the contents of the DCD to a patient.

2 . The system of claim 1 , wherein the NFT comprises a unique identifier associated with the DCD.

3 . The system of claim 2 , wherein the unique identifier comprises an owner address associated with the patient.

4 . The system of claim 3 , wherein the owner address comprises a first bit field representing the patient and a second bit field representing the state of the DCD.

5 . The system of claim 4 , wherein the second bit field is updated to represent changes in the state of the DCD throughout its lifecycle.

6 . The system of claim 1 , wherein operations further include creating a ledger entry associated with the NFT based on at least one chamber of the DCD.

7 . The system of claim 1 , wherein updating the state of the NFT comprises recording one or more of: manufacturing data, shipping data, storage data, and administration data.

8 . The system of claim 1 , wherein the operations further include authenticating an owner of the DCD using the NFT before allowing administration of the contents.

9 . The system of claim 8 , wherein authenticating the owner comprises verifying biometric data of the patient.

10 . The system of claim 1 , wherein the operations further include restricting use of the DCD to a specific geographic location based on information stored in the NFT.

11 . The system of claim 1 , wherein the NFT includes off-chain pointers to additional data related to the DCD.

12 . The system of claim 1 , wherein the notarized ledger is a blockchain.

13 . The system of claim 1 , wherein the operations further include managing the NFT via at least one smart contract.

14 . The system of claim 1 , wherein the NFT represents ownership rights of the DCD.

15 . The system of claim 1 , wherein burning the NFT comprises calling a burn API of the NFT.

16 . The system of claim 1 , wherein the operations further include transferring the NFT to different addresses to indicate changes in the state of the DCD.

17 . The system of claim 1 , wherein the operations further include providing controlled access to DCD data stored in the NFT to authorized third parties.

18 . The system of claim 1 , wherein the NFT includes metadata describing characteristics of the DCD.

19 . The system of claim 1 , wherein the operations further include integrating the NFT into a larger blockchain infrastructure associated with a healthcare provider.

20 . The system of claim 1 , wherein operations further include using the burned NFT as part of an audit trail for the DCD.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2025
From: NANTWORKS, LLC
To: IMMUNITYBIO, INC.
Reel/Frame 073527/0954 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 5, 2025
From: WITCHEY, NICHOLAS J.
To: NANTWORKS, LLC
Reel/Frame 071940/0149 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 5, 2025
From: SOON-SHIONG, PATRICK
To: IMMUNITYBIO, INC
Reel/Frame 071940/0240 →
Continuity (2)
Continuation 18656535 · May 6, 2024
Related Publication 20250342930A1 · Nov 6, 2025
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