Growth hormone secretagogues
The invention relates to compounds of formula I which are useful for elevating the plasma level of growth hormone in a mammal as well for the treatment of growth hormone secretion deficiency, growth retardation in child and metabolic disorders associated with growth hormone secretion deficiency.
1. A compound which is
2. A pharmaceutical composition, comprising a compound of claim 1 .
3. The composition of claim 2 , in combination with a pharmaceutically acceptable carrier.
4. The composition of claim 2 , in combination with an additional growth hormone secretagogue.
5. A method for elevating the plasma level of growth hormone in a mammal comprising administering to a mammal a therapeutically effective amount of a compound according to claim 1 so as to elevate the plasma level of growth hormone.
6. A method for the treatment of growth hormone secretion deficiency comprising administering to a mammal a therapeutically effective amount of a compound according to claim 1 so as to treat the growth hormone secretion deficiency.
7. A method for the treatment of growth retardation in a child comprising administering to a patient a therapeutically effective amount of a compound according to claim 1 so as to treat the growth retardation.
8. A method for the treatment of metabolic disorders associated with growth hormone secretion deficiency comprising administering to a patient a therapeutically effective amount of a compound according to claim 1 so as to treat the metabolic disorder.
9. The compound of claim 1 in the form a salt thereof.