Process for preparation of chemically stable, dry-flow, low compact, dust free, soluble granules of phosphoroamidothioates
Dry flow, low compact, dust free, soluble granules of phosphoroamidothioates, preferably acephate, are produced by the process of 1) pre-mixing technical grade phosphoroamidothioate with specified adjuvants and other inert ingredients; 2) grinding to produce a ground product having a preferred particle size of 5 microns to 10 microns; 3) post-mixing; 4) granulating; 5) drying; 6) sizing to required length, preferably 1.5 to 3.0 mm; 7) and sieving to remove the fines to get the desired dust free soluble granule.
1. A process for preparing soluble granules comprising
a) premixing 40 to 98 wt. % an insecticidally active compound of the following formula:
wherein R and R 1 individually are an alkyl, alkenyl or alkynyl group containing up to 6 carbon atoms, R 2 is hydrogen, an alkyl group containing 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8 carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or an alkynyl group containing 3 to 18 carbon atoms, R 3 is hydrogen or an alkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;
0.1-5.0 wt. % a dispersing agent; 0.1-3.0 wt. % a wetting agent; 0.1-3.0 wt. % a binding agent; 0.01-0.08 wt. % an antifoaming agent; 0.01-10.0 wt. % a disintegrating agent; 0.01-1.0 wt. % a stabilizer; and fillers to make 100 wt. %, to form a premix comprising essentially 95-99% solids and 1-5% moisture and/or solids;
b) grinding said premix to produce a ground product having a predetermined particle size;
c) post-mixing said ground product to produce a mixture;
d) granulating said mixture to produce granules;
e) drying said granules to produce dry granules;
f) sizing said dry granules to produce sized granules having a predetermined length and a predetermined diameter; and
g) sieving said sized granules to separate fines which are less than said predetermined length and said predetermined diameter.
2. The process of claim 1 , wherein said ground product has a predetermined particle size of 5-10 microns.
3. The process of claim 1 , wherein said dry granules have a predetermined length of 1.5-3.0 mm.
4. The process of claim 1 , wherein said dry granules have a predetermined diameter of 0.5 to 1.0 mm.
5. The process claimed in claim 1 , wherein said fillers are solids in powder form.
6. The process of claim 1 , wherein said binding agent is a blend of sucrose and starch derivatives.
7. The process of claim 1 , wherein said wetting agent is selected from the group comprising calcium salt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
8. The process of claim 1 , wherein said dispersing agent is a derivative of sulfonated fatty alcohol.
9. The process of claim 1 , wherein said disintegrating agent is a swelling type clay selected from the group comprising bentonite and zeolite.
10. The process of claim 1 , wherein said antifoaming agent is silicon oil derivative.
11. The process of claim 1 , wherein said stabilizer is a salt of a higher fatty acid.
12. The process of claim 1 , wherein said fillers are selected from the group comprising precipitated silica and kaoline.
13. The process of claim 1 , wherein said granulation is accomplished by passing said mixture through an orifice having and inlet and an outlet.
14. The process of claim 13 , wherein said inlet has a temperature of 30-35° C.
15. The process of claim 13 , wherein said outlet has a temperature of 40-45° C.
16. The process of claim 1 , wherein said drying is accomplished by passing said granules though an air chamber.
17. The process of claim 1 , wherein said grinding is accomplished by a microniser.
18. The process of claim 1 , wherein said sizing is accomplished by an oscillating cutter.
19. The process of claim 1 , wherein said insecticidally active compound is acephate.
20. The process of claim 1 , further comprising;
h) recycling said fines into step d).
21. The process of claim 20 , wherein said insecticidally active compound is acephate.
22. The process of claim 21 , wherein said ground product has a predetermined particle size of 5-10 microns.
23. The process of claim 22 , wherein said dry granules have a predetermined length of 1.5-3.0 mm and a predetermined diameter of 0.5 to 1.0 mm.
24. The process of claim 23 , wherein said binding agent is a blend of sucrose and starch derivatives.
25. The process of claim 24 , wherein said wetting agent is selected from the group comprising calcium salt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
26. The process of claim 25 , wherein said dispersing agent is a derivative of sulfonated fatty alcohol.
27. The process of claim 26 , wherein said disintegrating agent is a swelling type clay selected from the group comprising bentonite and zeolite.
28. The process of claim 27 , wherein said antifoaming agent is silicon oil derivative.
29. The process of claim 28 , wherein said stabilizer is a salt of a higher fatty acid.
30. The process of claim 29 , wherein said fillers are selected from the group comprising precipitated silica and kaoline.
31. The process of claim 20 , wherein said granulation is accomplished by passing said mixture through an orifice having and inlet and an outlet.
32. The process of claim 31 , wherein said inlet has a temperature of 30-35° C. and said outlet has a temperature of 40-45° C.
33. The process of claim 32 , wherein said drying is accomplished by passing said granules though an air chamber.
34. The process of claim 33 , wherein said grinding is accomplished by a microniser.
35. The process of claim 34 , wherein said sizing is accomplished by an oscillating cutter.
36. A process for preparing soluble granules comprising
a) preparing a dry premix by premixing 40 to 98 wt. % an insecticidally active compound of the following formula:
wherein R and R 1 individually are an alkyl, alkenyl or alkynyl group containing up to 6 carbon atoms, R 2 is hydrogen, an alkyl group containing 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8 carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or an alkynyl group containing 3 to 18 carbon atoms, R 3 is hydrogen or an alkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;
0.1-3.0 wt. % a wetting agent and a filler to make 100 wt. %;
b) grinding said dry premix to produce a ground product having a predetermined particle size;
c) post-mixing said ground product to produce a mixture;
d) granulating said mixture to produce granules;
e) drying said granules to produce dry granules;
f) sizing said dry granules to produce granules having a predetermined length and a predetermined diameter; and
g) sieving said sized granules to separate fines which are less than said predetermined length and said predetermined diameter.
37. The process of claim 36 , wherein said wetting agent is selected from the group comprising calcium salt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
38. The process of claim 36 , wherein said filler is selected from the group comprising precipitated silica and kaoline.
39. The process of claim 38 , wherein said wetting agent is selected from the group comprising calcium salt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
40. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.1-5.0 wt. % a dispersing agent.
41. The process of claim 40 , wherein said dispersing agent is a derivative of sulfonated fatty alcohol.
42. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.1-3.0 wt. % a binding agent.
43. The process of claim 42 , wherein said binding agent is a blend of sucrose and starch derivatives.
44. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.01-0.08 wt. % an antifoaming agent.
45. The process of claim 44 , wherein said antifoaming agent is a silicon oil derivative.
46. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.01-10 wt. % a disintegrating agent.
47. The process of claim 46 , wherein said disintegrating agent is a swelling type clay selected from the group comprising bentonite and zeolite.
48. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.01-1.0 wt. % a stabilizer.
49. The process of claim 48 , wherein said stabilizer is a salt of a higher fatty acid.
50. The process of claim 36 , wherein said insecticidally active compound is acephate.
51. The process of claim 36 , further comprising;
h) recycling said fines into step d).
52. The process of claim 51 , wherein said insecticidally active compound is acephate.
53. The process of claim 36 , wherein said dry premix is substantially free from water or solvent.
54. The process of claim 36 , wherein said step of preparing said dry premix further comprises premixing 0.1-5.0 wt. % a dispersing agent, 0.1-3.0 wt. % a binding agent, 0.01-0.08 wt. % an antifoaming agent, 0.01-10 wt. % a disintegrating agent, 0.01-1.0 wt. % a stabilizer.
55. The process of claim 54 , wherein said insecticidally active compound is acephate.
56. The process of claim 55 , wherein said dispersing agent is a derivative of sulfonated fatty alcohol, said binding agent is a blend of socrose and starch derivatives, said antifoaming agent is a silicon oil derivative, said disintegrating agent is selected from the group comprising bentonite and zeolite, and said stabilizer is a salt of a higher fatty acid.
57. The process of claim 56 , wherein said dry premix is substantially free of water or solvent.
58. The process of claim 54 , wherein said dry premix is substantially free of water or solvent.
59. A process for preparing soluble granules consisting essentially,
a) preparing a dry premix by premixing 40 to 98 wt. % an insecticidally active compound of the following formula:
wherein R and R 1 individually are an alkyl, alkenyl or alkynyl group containing up to 6 carbon atoms, R 2 is hydrogen, an alkyl group containing 1 to 18 carbon atoms, a cycloalkyl group containing 3 to 8 carbon atoms, an alkenyl group containing 2 to 18 carbon atoms or an alkynyl group containing 3 to 18 carbon atoms, R 3 is hydrogen or an alkyl group containing 1 to 6 carbon atoms, and Y is oxygen or sulfur;
0.1-5.0 wt. % a dispersing agent; 0.1-3.0 wt. % a wetting agent; 0.1-3.0 wt. % a binding agent; 0.01-0.08 wt. % an antifoaming agent; 0.01-10.0 wt. % a disintegrating agent; 0.01-1.0 wt. % a stabilizer; and a filler to make 100 wt. %;
b) grinding said dry premix to produce a ground product having a predetermined particle size;
c) post-mixing said ground product to produce a mixture;
d) granulating said mixture to produce granules;
e) drying said granules to produce dry granules;
f) sizing said dry granules to produce granules having a predetermined length and a predetermined diameter; and
g) sieving said sized granules to separate fines which are less than said predetermined length and said predetermined diameter.
60. The process of claim 59 , wherein said binding agent is a blend of sucrose and starch derivatives.
61. The process of claim 59 , wherein said wetting agent is selected from the group comprising calcium salt of alkyl aryl sulphonate and sodium salt of alkyl aryl sulphonate.
62. The process of claim 59 , wherein said dispersing agent is a derivative of sulfonated fatty alcohol.
63. The process of claim 59 , wherein said disintegrating agent is a swelling type clay selected from the group comprising bentonite and zeolite.
64. The process of claim 59 , wherein said antifoaming agent is silicon oil derivative.
65. The process of claim 59 , wherein said stabilizer is a salt of a higher fatty acid.
66. The process of claim 59 , wherein said filler is selected from the group comprising precipitated silica and kaoline.
67. The process of claim 59 , wherein said insecticidally active compound is acephate.
68. The process of claim 59 , wherein said dry premix is substantially free of water or solvent.