Ascorbate-isoquercetin compositions
The present invention relates to novel compositions containing ascorbic acid with an increased bioavailability of this vitamin. These compositions are useful as food supplements possessing preventive properties against damages of human organs, including skin, tissues and cells due to oxidative stress or damages.
1. A method of extending the biological activity lifetime of ascorbic acid, ascorbate or a derivative thereof, comprising administering ascorbic acid, ascorbate or a derivative thereof in combination with one or more of quercetin-3-O-glucoside (isoquercetin), quercetin-4′-glucoside, quercetin-3′-glucoside, or quercetin-7-glucoside, in a molar ratio of from about 2:1 to about 1:2.
2. The method of claim 1 , wherein said ascorbic acid or ascorbate is present in an amount ranging from 150 to 1000 mg in a daily dose.
3. A method according to claim 1 wherein said isoquercetin is in combination with ascorbic acid or a physiologically active ascorbate in the form of its sodium, calcium, or other mineral or organic salt.
4. A method according to claim 1 wherein said isoquercetin is in combination with ascorbic acid or a mineral or organic salt thereof.
5. A method according to claim 1 wherein said combination further comprises a vitamin.
6. A method according to claim 1 wherein said combination further comprises a Mg, Ca, K, or Fe salt.
7. A method according to claim 1 wherein said combination further comprises a trace element.
8. A method according to claim 1 wherein said combination of ascorbic acid or ascorbate and isoquercetin is in a molar ratio of about 1:1.
9. A method according to claim 1 wherein said ascorbic acid or ascorbate is present in an amount ranging from 30 to 4000 mg in a daily dose.
10. A method according to claim 1 wherein said ascorbic acid or ascorbate is present in an amount ranging from 1500 to 3000 mg in a daily dose.