IP Library › Granted Patent US 7,045,626
Granted Patent B2
US 7,045,626 · App. 10/496,193 · Granted May 16, 2006

Quinoline derivatives, process for preparing them and use for the treatment of diseases mediated by s-CD23

Assignee: SmithKline Beecham p.l.c.
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Quick Facts
Patent No.
US 7,045,626
App. No.
10/496,193
Granted
May 16, 2006
Kind
B2
Abstract

A compound of formula (I): useful in the treatment and prophylaxis of conditions mediated by s-CD23

Claims (12)

1. A compound of formula (I):

2. A compound of formula (IA):

3. A pharmaceutical composition which comprises a compound according to claim 1 and optionally a pharmaceutically acceptable carrier therefor.

4. A process for preparing a compound according to claim 1 which process comprises:

(a) deprotecting a compound of formula (II):

wherein P is a protecting group selected from the group consisting of benzyl, tetrahydropyranyl and p-methoxybenzyl, or

(b) formylating a compound of formula (III):

or (c) oxidising a compound of formula (X):

5. A compound of formula (II):

wherein P is a protecting group selected from the group consisting of benzyl, tetrahydropyranyl and p-methoxybenzyl.

6. A compound of formula (III):

7. A compound of formula (X):

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 14, 2004
From: BEST, DESMOND JOHN; BRUTON, GORDON; ORLEK, BARRY SIDNEY
To: SMITHKLINE BEECHAM P.L.C.
Reel/Frame 014851/0808 →
Priority Claims (1)
GB 0128378.7 · Nov 27, 2001 · national
Continuity (1)
Related Publication 20050085505A1 · Apr 21, 2005