IP Library › Granted Patent US 7,049,410
Granted Patent B2
US 7,049,410 · App. 10/302,868 · Granted May 23, 2006

Antibodies to a novel EGF-receptor related protein (ERRP)

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,049,410
App. No.
10/302,868
Granted
May 23, 2006
Kind
B2
Abstract

This invention relates to ERRP (EGF-Receptor Related Protein) specific antibodies that could be used 1) to study the functional properties of ERRP and; 2) as a diagnostic and prognostic tool for malignancies. Preferably, the antibody reacts with a segment of ERRP containing 15 amino acids (SEQ ID NO: 4) that possesses the most antigenic property.

Claims (27)

1. An antibody that specifically binds to the polypeptide of SEQ ID NO: 3.

2. The antibody of claim 1 , wherein the antibody is monoclonal.

3. The antibody of claim 1 , wherein the antibody is polyclonal.

4. An antibody that specifically binds to the polypeptide of SEQ ID NO: 4.

5. The antibody of claim 4 , wherein the antibody is monoclonal.

6. The antibody of claim 4 , wherein the antibody is polyclonal.

7. A method of making an antibody that specifically binds to the polypeptide of SEQ ID NO: 2 comprising

providing the polypeptide of SEQ ID NO: 2;

injecting the polypeptide into an animal;

harvesting the animal's blood; and

purifying the antibody from the blood.

8. The method of claim 7 wherein the animal is selected from the group consisting of sheep, goats, mice, rabbits, and rats.

9. The method of claim 7 wherein the purifying step is accomplished by affinity separation.

10. A method of making an antibody that specifically binds to the polypeptide of SEQ ID NO: 3 comprising

providing the polypeptide of SEQ ID NO: 3;

injecting the polypeptide into an animal;

harvesting the animal's blood; and

purifying the antibody from the blood.

11. The method of claim 10 wherein the animal is selected from the group consisting of sheep, goats, mice, rabbits, and rats.

12. The method of claim 10 wherein the purifying step is accomplished by affinity separation.

13. A method of making an antibody that specifically binds to the polypeptide of SEQ ID NO: 4 comprising

providing the polypeptide of SEQ ID NO: 4;

injecting the polypeptide into an animal;

harvesting the animal's blood; and

purifying the antibody from the blood.

14. The method of claim 13 , wherein the animal is selected from the group consisting of sheep, goats, mice, rabbits, and rats.

15. The method of claim 13 , wherein the purifying step is accomplished by affinity separation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2003
From: MAJUMDAR, ADHIP
To: U.S. DEPARTMENT OF VETERANS AFFAIRS; WAYNE STATE UNIVERSITY
Reel/Frame 013813/0417 →
Continuity (5)
Continuation In Part 0986752100 · May 31, 2001
Division 0957045400 · May 12, 2000
Provisional Application 6013420000 · May 14, 1999
Provisional Application 6033407700 · Nov 30, 2001
Related Publication 20030096373A1 · May 22, 2003